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HDR-IORT for Retroperitoneal Sarcomas

  • Chapter
Intraoperative Irradiation

Part of the book series: Current Clinical Oncology ((CCO))

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Abstract

It has been clearly documented that complete resection plus radiation therapy can locally control the overwhelming majority of soft-tissue sarcomas of the extremity and superficial trunk (1-18). In this regard, the radiation-therapy approach can be either by external beam, brachytherapy, or a combination of both (1-18). The value of adjuvant brachytherapy over surgery alone for high-grade lesions has been demonstrated in a prospective randomized trial at Memorial Sloan Kettering Cancer Center (MSKCC) (19,20). Suit (2,3,9,12) has demonstrated excellent local control for low-grade lesions using surgery with external-beam irradiation (EBRT). Other investigators have successfully employed a combination of adjuvant EBRT and brachytherapy (8,10,11,17,18). Local control rates between 80 and 100% have been reported when both surgery and radiotherapy are properly integrated.

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Authors
  1. Louis B. Harrison
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  2. Lowell Anderson
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  3. Carol White
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  4. Murray F. Brennan
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Editor information

Editors and Affiliations

  1. Mayo Clinic and Mayo Medical School, Rochester, MN, USA

    Leonard L. Gunderson MD, MS (Professor and Chair of Oncology) (Professor and Chair of Oncology)

  2. Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    Christopher G. Willet MD

  3. Albert Einstein College of Medicine and Beth Israel Cancer Center, New York, NY, USA

    Louis B. Harrison MD

  4. University Hospital Gregorio Marañón, Madrid, Spain

    Felipe A. Calvo MD (Chair of Oncology) (Chair of Oncology)

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© 1999 Springer Science+Business Media New York

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Harrison, L.B., Anderson, L., White, C., Brennan, M.F. (1999). HDR-IORT for Retroperitoneal Sarcomas. In: Gunderson, L.L., Willet, C.G., Harrison, L.B., Calvo, F.A. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-696-6_19

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  • DOI: https://doi.org/10.1007/978-1-59259-696-6_19

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5576-3

  • Online ISBN: 978-1-59259-696-6

  • eBook Packages: Springer Book Archive

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