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General Rationale and Historical Perspective of Intraoperative Irradiation

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Book cover Intraoperative Irradiation

Part of the book series: Current Clinical Oncology ((CCO))

Abstract

Most of the major advances in clinical applications of radiation therapy in the treatment of cancer have been because of differences in dose distribution between tumor and normal tissue. For most tumor types, the likelihood of achieving local tumor control improves if increasing irradiation doses can be delivered to the tumor mass. However, in many clinical situations, the dose that can be delivered safely to the tumor volume is limited by the normal tissues that are in close proximity to the tumor.

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Authors
  1. Leonard L. Gunderson
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  2. Felipe A. Calvo
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  3. Christopher G. Willett
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  4. Louis B. Harrison
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  5. Manuel Santos
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Editor information

Editors and Affiliations

  1. Mayo Clinic and Mayo Medical School, Rochester, MN, USA

    Leonard L. Gunderson MD, MS (Professor and Chair of Oncology) (Professor and Chair of Oncology)

  2. Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    Christopher G. Willet MD

  3. Albert Einstein College of Medicine and Beth Israel Cancer Center, New York, NY, USA

    Louis B. Harrison MD

  4. University Hospital Gregorio Marañón, Madrid, Spain

    Felipe A. Calvo MD (Chair of Oncology) (Chair of Oncology)

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Gunderson, L.L., Calvo, F.A., Willett, C.G., Harrison, L.B., Santos, M. (1999). General Rationale and Historical Perspective of Intraoperative Irradiation. In: Gunderson, L.L., Willet, C.G., Harrison, L.B., Calvo, F.A. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-696-6_1

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  • DOI: https://doi.org/10.1007/978-1-59259-696-6_1

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5576-3

  • Online ISBN: 978-1-59259-696-6

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