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Handbook of Cancer Vaccines pp 297–316Cite as

Chaperone Proteins/Heat Shock Proteins As Anticancer Vaccines

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Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

Abstract

The chaperone proteins, a family whose members include heat shock proteins (HSPs) and stress proteins, are among the most abundant proteins found in cells. The fundamental roles played by these proteins are so essential to cell survival that they have evolutionary origins as old as Archaebacter. Despite the long history of their existence, scientists have only recently learned of the pivotal activities possessed by chaperone proteins, leading up to their use as anticancer vaccines.

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Authors
  1. Michael W. Graner PhD
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  2. Emmanuel Katsanis MD
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Editors and Affiliations

  1. Duke University Medical Center, Durham, NC, USA

    Michael A. Morse MD , Timothy M. Clay PhD  & H. Kim Lyerly MD ,  & 

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Graner, M.W., Katsanis, E. (2004). Chaperone Proteins/Heat Shock Proteins As Anticancer Vaccines. In: Morse, M.A., Clay, T.M., Lyerly, H.K. (eds) Handbook of Cancer Vaccines. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-680-5_20

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  • DOI: https://doi.org/10.1007/978-1-59259-680-5_20

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9818-9

  • Online ISBN: 978-1-59259-680-5

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