The organophosphonate nerve agents are the deadliest of the classical chemical warfare agents. They have been used on the battlefield and also in two terrorist attacks. Since excellent antidotal therapy for these agents exists, and since it must be applied rapidly in order to save patients, physicians must familiarize themselves with the appropriate pathophysiology and the rationale for these antidotes.
KeywordsStatus Epilepticus Nerve Agent Cholinergic Synapse Pyridostigmine Bromide Chemical Weapon Convention
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