Abstract
Coronary heart disease (CHD) continues to be a dominant cause of mortality in the United States, claiming 500,000 lives of both sexes annually (1). Since the 1980s, the cardiovascular mortality rate in women has remained static, despite the relative decline in cardiovascular mortality in men (1). Several factors may account for this difference in outcome, including differences in risk factor profiles (especially smoking) and the biology of coronary artery disease (CAD; especially older age occurrence in women vs men). Another explanation might be the presence of gender differences in the diagnosis and management of CHD (2), such that coronary disease is underdiagnosed and undertreated in women in comparison to men (3,4).
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Marwick, T.H., Chan, J. (2004). Gender Bias. In: Shaw, L.J., Redberg, R.F. (eds) Coronary Disease in Women. Contemporary Cardiology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-645-4_22
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