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Endocrinology pp 325–348Cite as

The Endocrine System of the Gastrointestinal Tract

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Abstract

The movement of food through the gastrointestinal tract requires coordination with the processes of digestion and absorption. Integration is also achieved with energy balance, fat storage, appetite regulation, and memory. The gut is exposed to the exterior, and mucosal integrity must be maintained. In order to accomplish this, a complex control system has evolved. The complexities of this system have led to it being characterized as the little brain. This involves a specialized enteric nervous system and an enteroendocrine system, which are integrated with each other and have a bidirectional communication with the central nervous system. This integration may at least in part be the result of the evolution of a common pool of messenger peptides and receptors.

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Authors
  1. Gary A. Wittert MB BCh MD
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  2. Robert Fraser MB BS PhD
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  3. John E. Morley MB BCh
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Editors and Affiliations

  1. Oregon Regional Primate Research Center, Beaverton, USA

    P. Michael Conn

  2. Oregon Health Sciences University, Portland, OR, USA

    P. Michael Conn

  3. Division of Endocrinology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA

    Shlomo Melmed

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Wittert, G.A., Fraser, R., Morley, J.E. (1997). The Endocrine System of the Gastrointestinal Tract. In: Conn, P.M., Melmed, S. (eds) Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-641-6_21

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  • DOI: https://doi.org/10.1007/978-1-59259-641-6_21

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