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Calcium-Regulating Hormones

Vitamin D and Parathyroid Hormone

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Abstract

This chapter will describe the structure and actions of vitamin D, which is essential for maintaining a positive calcium balance and skeletal integrity, and the parathyroid hormone (PTH) responsible for minute-to-minute maintenance of calcium homeostasis, which is critical for neuromuscular activity.

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References

  • Clemens TL, Adams JS. Vitamin D and metabolites. In: Favus MJ ed. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 2nd ed., New York: Raven Press, 1993: 103.

    Google Scholar 

  • Goltzman D, Hendy GN. Parathyroid hormone. In: Becker KL, ed. Principles and Practice of Endocrinology and Metabolism, 2nd ed. Philadelphia: JB Lippincott, 1995: 455.

    Google Scholar 

  • Haussier MR, Jurutka PW, Hsieh J-C, Thompson PD, Selznick SH, Haussler CA, Whitfield GK. New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone. Bone 1995; 17 supp1:33S.

    Google Scholar 

  • Levine MA, Schwindinger WF, Downs RW Jr, Moses AM. Pseudohypoparathyroidism. Clinical, biochemical, and molecular features. In: Bilezikian JP, Marcus R, Levine MA, eds. The Parathyroids. Basic and Clinical Concepts. New York: Raven, 1994: 781.

    Google Scholar 

  • Minghetti PP, Norman AW. 1,25(OH)2-Vitamin D3 receptors: gene regulation and genetic circuitry. FASEB J 1988; 2: 3043.

    Google Scholar 

  • Nussbaum SR, Potts JT Jr. Advances in immunoassays for parathyroid hormone. Clinical applications to skeletal disorders of bone and mineral metabolism. In: Bilezikian JP, Marcus R, Levine MA, eds. The Parathyroids. Basic and Clinical Concepts. New York: Raven, 1994: 157.

    Google Scholar 

  • Papapoulos SE, Lewin IG, Clemens TL, Hendy GN, O’Riordan JLH. Vitamin D. In: Gray CH, James VHT, eds. Hormones in Blood. 3rd ed., vol 3. London: Academic, 1979: 53.

    Google Scholar 

  • Pike JW. Molecular mechanisms of cellular response to the vitamin D3 hormone. In: Coe FL, Favus MJ, eds. Disorders of Bone and Mineral Metabolism. New York: Raven, 1992: 163.

    Google Scholar 

  • Yu J, Papavasiliou V, Rhim J, Goltzman D, Kremer R. Vitamin D analogs: new therapeutic agents for the treatment of squamous cancer and its associated hypercalcemia. Anti-Cancer Drugs 1995; 6: 101

    Article  PubMed  CAS  Google Scholar 

  • Bassett HID, Thakker RV. Molecular genetics of calcium homeostasis. In: Thakker RV, ed. Genetic and Molecular Biological Aspects of Endocrine Disease. Baillière’s Clinical Endocrinology and Metabolism. London: Baillière Tindall, 1995: 581.

    Google Scholar 

  • Bilezikian JP, Marcus R, Levine MA, eds. The Parathyroids. Basic and Clinical Concepts. New York: Raven, 1994.

    Google Scholar 

  • Bouillon R, Okamura WH, Norman AW. Structure–function relationships in the vitamin D endocrine system. Endocr Rev 1995; 16: 200.

    PubMed  CAS  Google Scholar 

  • Brown EM, Pollak M, Seidman CE, Seidman JG, Chou Y-HC, Riccardi D, Hebert SC. Calcium-sensing cell-surface receptors. N Engl J Med 1995; 333: 234–323

    Article  PubMed  CAS  Google Scholar 

  • Favus MJ, ed. Primer on Metabolic Bone Diseases and Disorders of Mineral Metabolism, 3rd ed. New York: Raven, 1996.

    Google Scholar 

  • Halloran BP, Nissenson RA, eds. Parathyroid Hormone-Related Peptide: Normal Physiology and Its Role in Cancer. Boca Raton: CRC, 1992.

    Google Scholar 

  • Hendy GN, Arnold A. Molecular basis of PTH overexpression. In: Bilezikian JP, Raisz LG, Rodan GA, eds. Principles of Bone Biology. San Diego: Academic, 1996: 757.

    Google Scholar 

  • Holick MF. Noncalcemic actions of 1,25-dihydroxyvitamin D3 and clinical applications. Bone 1995; 17 supp1:107S.

    Google Scholar 

  • Orloff JF, Stewart AF. Editorial: The carboxy-terminus of parathyroid hormone—inert or invaluable? Endocrinology 1995: 4729.

    Google Scholar 

  • Ross TK, Darwish HM, Deluca HF. Molecular biology of vitamin D action. Vitam Horm 1994; 49: 281.

    Article  PubMed  CAS  Google Scholar 

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© 1997 Springer Science+Business Media New York

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Hendy, G.N. (1997). Calcium-Regulating Hormones. In: Conn, P.M., Melmed, S. (eds) Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-641-6_20

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  • DOI: https://doi.org/10.1007/978-1-59259-641-6_20

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5137-6

  • Online ISBN: 978-1-59259-641-6

  • eBook Packages: Springer Book Archive

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