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Current Treatment Modalities for Brain Tumor

Surgery, Radiation, and Chemotherapy

  • Chapter
Gene Therapy for Neurological Disorders and Brain Tumors

Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

Because they are relatively refractory to current treatments, brain tumors are particularly promising candidates for genetic therapy. For many malignant brain tumors the side effects of even oncologically successful therapy still compromise quality of life. To illustrate the challenges faced, this chapter presents an outline of the current therapy of brain tumors in the context of their histopathological classification (1–3). Currently available therapeutic interventions for brain tumors include tumor biopsy for the purpose of diagnosis, and open operation for the reduction of tumor mass to the maximum extent consistent with preservation of neurologic function, chemotherapy, and radiation. This chapter reviews the application of these treatment modalities to intracranial tumors.

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Authors
  1. Stephen B. Tatter
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  2. Griffith R. Harsh IV
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Editors and Affiliations

  1. Molecular Neuro-Oncology, Neurosurgical Service, Massachussetts General Hospital, Harvard Medical School, Boston, MA, USA

    E. Antonio Chiocca MD, PhD

  2. Neurogenetics Unit, Massachussetts General Hospital, Harvard Medical Center, Boston, MA, USA

    Xandra O. Breakefield PhD

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Tatter, S.B., Harsh, G.R. (1998). Current Treatment Modalities for Brain Tumor. In: Chiocca, E.A., Breakefield, X.O. (eds) Gene Therapy for Neurological Disorders and Brain Tumors. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-478-8_10

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