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Transrectal Ultrasound-Guided Prostate Brachytherapy

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Image-Guided Diagnosis and Treatment of Cancer

Abstract

The most common solid malignancy in men, prostate cancer is now being diagnosed, in most men, in the very earliest stages, in the United States (1). This surge in earlier-stage diagnosis is the result, in large part, of the introduction and increased use of the prostate-specific antigen (PSA) blood test (2). Traditional therapeutic options of radical prostatectomy and external beam radiation therapy have come under more scrutiny because PSA tests in follow-up reveal disease control rates have been found to be lower than previously thought (3–6). Neither radical prostatectomy nor external beam radiation therapy (EBRT) appear to result in superior cancer control, vs each other, when major pretreatment prognostic variables are taken into consideration (7–11). Moreover, patient-reported toxicity rates have been found to be considerably higher than the previous physician-reported rates (12).

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Sylvester, J., Blasko, J., Grimm, P. (2003). Transrectal Ultrasound-Guided Prostate Brachytherapy. In: D’Amico, A.V., Loeffler, J.S., Harris, J.R. (eds) Image-Guided Diagnosis and Treatment of Cancer. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-422-1_6

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