Abstract
The research on biomaterials for hard-tissue implantation or replacement has expanded considerably during the last ten years. To establish a load-bearing unity of implant and hard tissue, the implant must be incorporated into the bone. However, to fulfill this function, the implant material must possess certain specific properties. The required properties can be classified roughly under the headings of biocompatibility, implant construction, and biomechanics.11 Biocompatibility deals with the interfacial reactions between biomaterials and tissue. Implant construction deals with the engineering of the implant as well as its mechanical properties, such as hardness and strength. Biomechanics is concerned with the mechanical-dynamic properties of an implant and surrounding tissues. For the safe application of implants, they must be evaluated for all these properties. This chapter focuses on the biocompatibility or interfacial analysis of materials for hard-tissue implantation.
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References
Black J: Biological Performance of Materials. Marcel Dekker, Inc., New York, NY, 1992.
Caulier H, Van der Waerden JPCM, Wolke JGC, et al: A histological and histomorphometrical evaluation of the application of screw-designed calcium phosphate (Ca-P) coated implants in the cancellous maxillary bone of the goat. J Biomed Mater Res 35: 19–30, 1997.
Corten FGA, Caulier H, Vand der Waerden JPCM, et al: Assessment of bone surrounding implants in goats: ex vivo measurements by dual X-ray absorptiometry. Biomaterials 18: 495–501, 1997.
Damien CJ, Parsons JR: Bone graft and bone graft substitutes: a review of current technology and applications. JAppl Biomater 2: 187–208, 1991.
Dhert WJA, Thomsen P, Blomgren AK, et al: Integration of press-fit implants in cortical bone: a study on interface kinetics. J Biomed Mater Res 41: 574–583, 1998.
Donath K, Breuner GA: A method for the study of undecalcified bones and teeth with attached soft tissue. J Oral Pathol 11: 318–326, 1982.
Eschberger DG, Eschberger J: Microradiography. In: von Recum AF, ed: Handbook of Biomaterials Evaluation. Taylor and Francis, Philadelphia, PA, 1999: 743–754.
Heimke G: The aspects and modes of fixation of bone replacements. In: Heimke G, ed: Osseo-integrated Implants Volume 1. CRC Press, Boca Raton, FL, 1990: 1–30.
Hulshoff JEG, Jansen JA: Initial interfacial healing events around calcium phosphate (Ca-P) coated oral implants. Clin Oral Implants Res 8: 393–400, 1997.
Jansen JA, Dhert WJA, van der Waerden JPCM, et al: A semi-quantitative and semi-qualitative histologic analysis method for the evaluation of implants. J Invest Surg 7: 123–134, 1994.
Osborn JS, Newesly H: Dynamic aspects of the implant-bone interface. In: Heimke G, ed: Dental Implants: Materials and Systems. Carl Hanser Verlag, Munich, Germany, 1980: 111–23.
Plenk H: Microscopic evaluation of hard tissue implants. In: Williams DF, ed: Techniques of Biocompatibility Testing Volume 1. CRC Press, Boca Raton, FL, 1986: 35–82.
Rahn BA: Intra vitam staining techniques. In: von Recum AF, ed: Handbook of Biomaterials Evaluation. Taylor and Francis, Philadelphia, PA, 1999: 727–738.
St balle K: Hydroxyapatite ceramic coating for bone implant fixation. Mechanical and histological studies in dogs. Acta Orthop Scand Suppl 255: 1–58, 1993.
Szmukler-Moncler S, Salama H, Reingewirtz Y, et al: Timing of loading and effect of micro-motion on bone-dental implant interface: review of experimental literature. J Biomed Mater Res (Appl Biomater) 43: 192–203, 1998.
Tencer AF: Osteocompatibility. In: von Recum AF, ed: Handbook of Biomaterials Evaluation. Taylor and Francis, Philadelphia, PA, 1999: 539–566.
Van der Lubbe HBM, Klein CPAT, de Groot K: A simple method for preparing thin histological sections of undecalcified plastic embedded bone with implants. Stain Technol 63: 171–177, 1988.
Van Oosterwijck H, Duyck J, Vander Sloten J, et al: The use of microfocus computerized tomography as a new technique for characterizing bone tissue around oral implants. J Oral Implantol 26: 5–12, 2000.
Vercaigne S, Wolke JGC, Naert I, et al: A histological evaluation of TiO2 grit-blasted and Ca-P magnetron sputter coated implants placed into the trabecular bone of the goat: part 2. Clin Oral Implants Res 11: 314–324, 2000.
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Jansen, J.A. (2003). Histological Analysis of Bone-Implant Interface. In: An, Y.H., Martin, K.L. (eds) Handbook of Histology Methods for Bone and Cartilage. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-417-7_26
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DOI: https://doi.org/10.1007/978-1-59259-417-7_26
Publisher Name: Humana Press, Totowa, NJ
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