Abstract
In 1912, S. A. Kinnear Wilson described hepatolenticular degeneration, which was later named “Wilson’s disease.” This autosomal recessive disease results in the deposition of excess copper in the body, especially in the brain and liver. Although our understanding of the clinical findings, laboratory abnormalities, molecular aspects, and treatment strategies is sophisticated, we still do not fully understand the pathogenesis of this fascinating disease. Inevitably fatal at the time of its description, Wilson’ s disease is now one of the most treatable hereditary neurologic disorders. Because it has a wide clinical spectrum and can be treated, Wilson’s disease should be considered in the differential diagnostic evaluation of patients seen by neurologists, psychiatrists, gastroenterologists, and other physicians.
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Gwinn-Hardy, K.A. (2000). Wilson’s Disease. In: Adler, C.H., Ahlskog, J.E. (eds) Parkinson’s Disease and Movement Disorders. Current Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-410-8_32
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DOI: https://doi.org/10.1007/978-1-59259-410-8_32
Publisher Name: Humana Press, Totowa, NJ
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