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Glycoprotein IIb/IIIa Receptor Blockade in Myocardial Infarction

Adjunctive Therapy to Percutaneous Coronary Interventions

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

In acute myocardial infarction, early, complete, and sustained restoration of blood flow in the occluded coronary artery can salvage myocardium at risk and improve survival. Randomized trials (1) as well as large registries (2,3) have shown that direct percutaneous transluminal coronary angioplasty (PTCA) is more efficacious in achieving this goal than thrombolysis. Additional placement of a stent improves long-term clinical outcome by reducing the need for target lesion revascularization but has no beneficial effect on the quality of reperfusion or the risk of early complications, such as death and reinfarction (4–6).

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  1. Franz-Josef Neumann MD
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Editors and Affiliations

  1. Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH, USA

    A. Michael Lincoff MD

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Neumann, FJ. (2003). Glycoprotein IIb/IIIa Receptor Blockade in Myocardial Infarction. In: Lincoff, A.M. (eds) Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease. Contemporary Cardiology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-376-7_12

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  • DOI: https://doi.org/10.1007/978-1-59259-376-7_12

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-408-1

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