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Serum Markers for Diagnosis and Risk Stratification in Acute Coronary Syndromes

  • Chapter
Management of Acute Coronary Syndromes

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Increasingly, both economic and clinical pressures necessitate accurate diagnosis and risk stratification of patients presenting to Emergency Departments (EDs) with suspected or actual acute coronary syndromes. Of the more than 6 million patients who present to EDs in the United States each year for evaluation of chest pain or anginal-equivalent symptoms, only about 15% are identified as having an acute myocardial infarction (MI). Conversely, the conventional evaluation, which includes a history, physical examination, and screening electrocardiogram (ECG) and creatine kinase (CK)-MB, may miss up to 25% of acute MIs at presentation. When unstable angina and nonacute coronary artery disease (CAD) presentations are accounted for, 40% of patients with chest pain do not have an underlying coronary etiology for their symptoms. The challenge is to identify both this group and the group at higher risk as early as possible, to promote rapid treatment of those who may benefit from specific medical or interventional approaches and to avoid costly hospitalization and testing in those at low risk.

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Authors
  1. L. Kristin Newby MD
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  2. W. Brian Gibler MD
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  3. Robert H. Christenson PhD
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  4. E. Magnus Ohman MD
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Editor information

Editors and Affiliations

  1. Cardiovascular Division, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    Christopher P. Cannon MD (Associate Professor of Medicine) (Associate Professor of Medicine)

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Newby, L.K., Gibler, W.B., Christenson, R.H., Ohman, E.M. (2003). Serum Markers for Diagnosis and Risk Stratification in Acute Coronary Syndromes. In: Cannon, C.P. (eds) Management of Acute Coronary Syndromes. Contemporary Cardiology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-351-4_7

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  • DOI: https://doi.org/10.1007/978-1-59259-351-4_7

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-58829-309-1

  • Online ISBN: 978-1-59259-351-4

  • eBook Packages: Springer Book Archive

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