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Acetylcholine Receptor Structure

  • Chapter
Myasthenia Gravis and Related Disorders

Part of the book series: Current Clinical Neurology ((CCNEU))

Abstract

Nicotinic acetylcholine receptors (AChRs) are acetylcholine-gated cation channels. They play a critical postsynaptic role in transmission between motor nerves and skeletal muscles and in autonomic ganglia (1,2). In the central nervous system, they also act presynaptically and extrasynaptically to modulate transmission by facilitating the release of many transmitters (3,4). In the skin (5), bronchial and vascular epithelia (6,7), and other nonneuronal tissues (8), they also mediate intercellular communication.

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  1. Jon M. Lindstrom
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  1. Departments of Neurology and Neurosciences, University Hospitals of Cleveland, Louis Stokes Cleveland Veterans Affairs Medical Center, Case Western Reserve University, Cleveland, OH, USA

    Henry J. Kaminski MD

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Lindstrom, J.M. (2003). Acetylcholine Receptor Structure. In: Kaminski, H.J. (eds) Myasthenia Gravis and Related Disorders. Current Clinical Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-341-5_2

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