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Mental and Behavioral Dysfunction in Movement Disorders pp 489–498Cite as

Dyskinesia in Patients with Schizophrenia Never Treated with Antipsychotics

Conceptual and Pathophysiological Implications

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Abstract

Schizophrenia is a devastating mental disorder. Despite the fact that abnormal movements have been described in patients with schizophrenia for more than a century (1,2), the significance and scope of this clinical reality is considerably under-represented in much of the medical literature. Because of the initial description of the extrapyramidal side effects of the first antipsychotic chlorpromazine by Steck in 1954 (3), and of tardive dyskinesia by Schonecker in 1957 (4), the focus of much research has been the presumed causal role of antipsychotics in the generation of abnormal movements in schizophrenia. Thus, although tardive dyskinesia has been the focus of a substantial number of studies, spontaneous dyskinesias in schizophrenia have received less consideration (5,6).

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Authors
  1. Christian Bocti MD
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  2. Deborah N. Black MD, MSc
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  3. John L. Waddington PhD, DSc
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Editor information

Editors and Affiliations

  1. Université du Québec à Montréal, Montréal, Canada

    Marc-André Bédard MSc, PhD

  2. Hôpital de la Salpêtrière, Paris, France

    Yves Agid MD, PhD

  3. Université de Montréal, Montréal, Canada

    Sylvain Chouinard MD  & Paul Lespérance MD, MSc  & 

  4. Columbia University, New York, NY, USA

    Stanley Fahn MD

  5. Tel-Aviv University Medical School, Tel-Aviv, Israel

    Amos D. Korczyn MD, MSc

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Bocti, C., Black, D.N., Waddington, J.L. (2003). Dyskinesia in Patients with Schizophrenia Never Treated with Antipsychotics. In: Bédard, MA., Agid, Y., Chouinard, S., Fahn, S., Korczyn, A.D., Lespérance, P. (eds) Mental and Behavioral Dysfunction in Movement Disorders. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-326-2_36

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  • DOI: https://doi.org/10.1007/978-1-59259-326-2_36

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