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Prevalence, Incidence, and Risk Factors for Dementia in Parkinson’s Disease

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Mental and Behavioral Dysfunction in Movement Disorders

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Abstract

Dementia in patients with idiopathic Parkinson’s disease (PD) increases functional impairment both directly, through the limitations imposed by cognitive impairment, and indirectly, due to increased susceptibility to the psychiatric side effects of dopaminergic and anticholinergic therapy, leading to restricted medication use and increased motor impairment. Cognitive impairment in PD has been shown to affect quality of life (1) and contribute to caregiver distress (2), and has been associated with nursing home placement (3). The development of dementia is also associated with reduced survival in patients with PD (4).

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Authors
  1. Gilberto Levy MD
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  2. Karen Marder MD, MPH
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Editor information

Editors and Affiliations

  1. Université du Québec à Montréal, Montréal, Canada

    Marc-André Bédard MSc, PhD

  2. Hôpital de la Salpêtrière, Paris, France

    Yves Agid MD, PhD

  3. Université de Montréal, Montréal, Canada

    Sylvain Chouinard MD  & Paul Lespérance MD, MSc  & 

  4. Columbia University, New York, NY, USA

    Stanley Fahn MD

  5. Tel-Aviv University Medical School, Tel-Aviv, Israel

    Amos D. Korczyn MD, MSc

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Levy, G., Marder, K. (2003). Prevalence, Incidence, and Risk Factors for Dementia in Parkinson’s Disease. In: Bédard, MA., Agid, Y., Chouinard, S., Fahn, S., Korczyn, A.D., Lespérance, P. (eds) Mental and Behavioral Dysfunction in Movement Disorders. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-326-2_20

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  • DOI: https://doi.org/10.1007/978-1-59259-326-2_20

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