Skip to main content

The Clinical Spectrum of Dementia in Movement Disorders

An Overview

  • Chapter
  • 200 Accesses

Abstract

It is estimated that in the next decade, dementia and movement disorders will become the second ranking cause of death after cardiovascular disease (1). Dementias and movement disorders are clinically and biologically overlapping manifestations of neurodegenerative disorders. Important areas of overlap are: (i) the spectrum of Alzheimer’s disease (AD), Parkinson’s disease (PD), dementia with Lewy bodies (DLB) (see Table 1); (ii) the spectrum of Pick’s disease (PiD), frontotemporal dementia (FTD), corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS) (see Table 2); (iii) distinct etiologies including Huntington’s chorea (HD), CreutzfeldtJakob disease (CJD) and vascular dementia (see Table 3).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Lilienfeld, D.E. and Perl, D.P. (1994) Projected neurodegenerative disease mortality among minorities in the United States. Neuroepidemiology 13, 179–186.

    Article  PubMed  CAS  Google Scholar 

  2. Parkinson, J. (1897) An essay on the Shaking Palsy, Sherwood, London.

    Google Scholar 

  3. Lieberman, A., Dziatolowski, M., Kupersmith, M., et al. (1979) Dementia in Parkinson’s disease. Ann. Neurol. 6, 355–359.

    Article  PubMed  CAS  Google Scholar 

  4. Brown, R.G. and Marsden, C.D. (1984) How common is dementia in Parkinson’s disease? Lancet 1, 1262–1265.

    Article  Google Scholar 

  5. Mayeux, R., Stern, Y., Rosenstein, R., et al. (1988) An estimate of the prevalence of dementia in idiopathic Parkinson’s disease. Arch. Neurol. 45, 260–262.

    Article  PubMed  CAS  Google Scholar 

  6. Marder, K., Ming-Xin, T., Cote, L., Stern, Y., and Mayeux, R. (1995) The frequency and associated risk factors for dementia in patients with Parkinson’s disease. Arch. Neurol. 52, 695–701.

    Article  PubMed  CAS  Google Scholar 

  7. Aarsland, D., Andersen, K., Larsen, J.P., et al. (2001) Risk of dementia in Parkinson’s disease: a community-based, prospective study. Neurology 56, 730–736.

    Article  PubMed  CAS  Google Scholar 

  8. Appell, J., Kertesz, A., and Fisman, M. (1982) A study of language functioning in Alzheimer patients. Brain Lang. 17, 73–91.

    Article  PubMed  CAS  Google Scholar 

  9. Brown, R.G. and Marsden, C.D. (1988) ‘Subcortical dementia’ : the neuropsychological evidence. Neuroscience 25, 363–387.

    Article  PubMed  CAS  Google Scholar 

  10. McHugh, P.R. and Folstein, M.F. (eds.) (1975) Psychiatric syndromes of Huntington’s chorea: a clinical and phenomenological study, in Psychiatric Aspects of Neurological Disease (Benson, D.F. and Blumer, D., eds.), Grune & Stratton, New York, pp. 267–285.

    Google Scholar 

  11. Albert, M.L., Feldman, R.G., and Willis, A.L. (1974) The ‘subcortical dementia’ of progressive supranuclear palsy. J. Neurol. Neurosurg. Psychiatry 37, 121–130.

    Article  PubMed  CAS  Google Scholar 

  12. Albert, M. (1978) Subcortical dementia, in Alzheimer’s Disease: Senile Dementia and Related Disorders (Katzman, R., Terry, R.D., and Bick, K.L., eds.), Raven Press, New York, pp. 173–180.

    Google Scholar 

  13. Dubois, B., Pillon, B., Legault, F., Agid, Y., and Lhermitte, F. (1988) Slowing of cognitive processing in progressive supranuclear palsy. Arch. Neurol. 45, 1194–1199.

    Article  PubMed  CAS  Google Scholar 

  14. Mayeux, R., Stern, Y., and Spanton, S. (1985) Heterogeneity in dementia of the Alzheimer type: evidence of subgroups. Neurology 35, 453–461.

    Article  PubMed  CAS  Google Scholar 

  15. Kosaka, K., Yoshimura, M., Ikeda, K., and Budka, H. (1984) Diffuse type of Lewy body disease: progressive dementia with abundant cortical Lewy bodies and senile changes of varying degree-a new disease? Clin. Neuropathol. 3, 185–192.

    PubMed  CAS  Google Scholar 

  16. Gibb, W.R.G., Esiri, M.M., and Lees, A.J. (1985) Clinical and pathological features of diffuse cortical Lewy body disease (Lewy body dementia). Brain 110, 1131–1153.

    Article  Google Scholar 

  17. McKeith, I.G., Galasko, D., Kosaka, K., et al. (1996) Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 47, 1113–1124.

    Article  PubMed  CAS  Google Scholar 

  18. del Ser, T., Hachinski, V., Merskey, H., and Munoz, D.G. (2001) Clinical and pathologic features of two groups of patients with dementia with Lewy bodies: effect of coexisting Alzheimer-type lesion load. Alzheimer Dis. Assoc. Disord. 15, 31–44.

    Article  PubMed  Google Scholar 

  19. Holmes, C., Cairns, N., Lantos, P., and Mann, A. (1999) Validity of current clinical criteria for Alzheimer’s disease, vascular dementia and dementia with Lewy bodies. Br. J. Psychiatry 174, 45–50.

    Article  PubMed  CAS  Google Scholar 

  20. Garruto, R.M., Fukatsu, R., Yanagihara, R., et al. (1984) Imaging of calcium and aluminum in neurofibrillary tanglebearing neurons in parkinsonism-dementia of Guam. Proc. Natl. Acad. Sci. USA 81, 1875–1879.

    Article  PubMed  CAS  Google Scholar 

  21. Akelaitis, A.J. (1944) Atrophy of basal ganglia in Pick’s disease. A clinicopathologic study. Arch. Neurol. Psychiatr 51, 27–34.

    Article  Google Scholar 

  22. Kertesz, A. and Munoz, D.G. (1998) Pick’s Disease and Pick Complex, Wiley-Liss, New York.

    Google Scholar 

  23. The Lund and Manchester Groups (1994) Clinical and neuropathological criteria for frontotemporal dementia. J. Neurol. Neurosurg. Psychiatry 57, 416–418.

    Article  Google Scholar 

  24. Kertesz, A., Hudson, L., Mackenzie, I.R.A., and Munoz, D.G. (1994) The pathology and nosology of primary progressive aphasia. Neurology 44, 2065–2072.

    Article  PubMed  CAS  Google Scholar 

  25. Frattali, C.M., Grafman, J., Patronas, N., Makhlouf, F., and Litvan, I. (2000) Language disturbances in corticobasal degeneration. Neurology 54, 990–992.

    Article  PubMed  CAS  Google Scholar 

  26. Kertesz, A., Martinez-Lage, P., Davidson, W., and Munoz, D.G. (2000) The corticobasal degeneration syndrome overlaps progressive aphasia and frontotemporal dementia. Neurology 55, 1368–1375.

    Article  PubMed  CAS  Google Scholar 

  27. Houlden, H., Baker, M., Morris, H.R., et al. (2001) Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology 56, 1702–1706.

    Article  PubMed  CAS  Google Scholar 

  28. Zhukareva, V., Vogelsberg-Ragaglia, V., Van Deerlin, V., et al. (2001) Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Ann. Neurol. 49, 165–175.

    Article  PubMed  CAS  Google Scholar 

  29. Grimes, D.A., Bergeron, C.B., and Lang, A.E. (1999) Motor neuron disease-inclusion dementia presenting as cortical-basal ganglionic degeneration. Mov. Disord. 14, 674–680.

    Article  PubMed  CAS  Google Scholar 

  30. Rebeiz, J.J., Kolodny, E.H., and Richardson, E.P. Jr. (1968) Corticodentatonigral degeneration with neuronal achromasia. Arch. Neurol. 18, 20–33.

    Article  PubMed  CAS  Google Scholar 

  31. Gibb, W.R.G., Luthert, P.J., and Marsden, C.D. (1989) Corticobasal degeneration. Brain 112, 1171–1192.

    Article  PubMed  Google Scholar 

  32. Riley, D.E., Lang, A.E., Lewis, M.B., et al. (1990) Cortical-basal ganglionic degeneration. Neurology 40, 1203–1212.

    Article  PubMed  CAS  Google Scholar 

  33. Rinne, J.O., Lee, M.S., Thompson, P.D., and Marsden, C.D. (1994) Corticobasal degeneration. Brain 117, 1183–1196.

    Article  PubMed  Google Scholar 

  34. Litvan, I., Agid, Y., Jankovic, J., et al. (1997) Accuracy of clinical criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome). Neurology 46, 1–9.

    Google Scholar 

  35. Bergeron, C., Davis, A., and Lang, A.E. (1998) Corticobasal ganglionic degeneration and progressive supranuclear palsy Presenting with cognitive decline. Brain Pathol. 8, 355–365.

    Article  PubMed  CAS  Google Scholar 

  36. Schneider, J.A., Watts, R.L., Gearing, M., Brewer, R.P., and Mina, S.S. (1997) Corticobasal degeneration: neuropathologic and clinical heterogeneity. Neurology 48, 959–969.

    Article  PubMed  CAS  Google Scholar 

  37. Pillon, B., Blin, J., Vidailhet, M., et al. (1995) The neuropsychological pattern of corticobasal degeneration: cornparison with progressive supranuclear palsy and Alzheimer’s disease. Neurology 45, 1477–1483.

    Article  PubMed  CAS  Google Scholar 

  38. Feany, M.B., Mattiace, L.A., and Dickson, D.W. (1996) Neuropathologic overlap of progressive supranuclear palsy, Pick’s disease and corticobasal degeneration. J. Neuropathol. Exp. Neurol. 55, 53–67.

    Article  PubMed  CAS  Google Scholar 

  39. Butters, N., Tarlow, S., and Cermak, L.S. (1976) A comparison of the information processing deficits of patients with Huntington’s chorea and Korsakoff’s syndrome. Cortex 12, 134–144.

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Kertesz, A. (2003). The Clinical Spectrum of Dementia in Movement Disorders. In: Bédard, MA., Agid, Y., Chouinard, S., Fahn, S., Korczyn, A.D., Lespérance, P. (eds) Mental and Behavioral Dysfunction in Movement Disorders. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-326-2_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-326-2_17

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-372-5

  • Online ISBN: 978-1-59259-326-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics