Skip to main content

Distinctive Features of Apraxia in Corticobasal Degeneration and Other Neurological Illnesses

  • Chapter
Mental and Behavioral Dysfunction in Movement Disorders
  • 197 Accesses

Abstract

Apraxia is a term used to denote a wide spectrum of higher order motor disorders that result from acquired brain disease affecting the performance of skilled and/or learned movements with or without preservation of the ability to perform the same movement outside the clinical setting in the appropriate situation or environment. The disturbance of purposive movements cannot be termed apraxia, however, if the patient suffers from any elementary motor or sensory deficit (i.e., paresis, dystonia, ataxia), which could fully explain the abnormal motor behavior, or if it results from a language comprehension disorder or from dementia (1,2). Nevertheless, praxic errors are well defined clinically and kinematically and can be superimposed on elementary motor disorders (3,4). Praxic disturbances may affect specific parts of the body (i.e., limb apraxia, buccofacial apraxia, gait apraxia) and may involve both sides of the body (i.e., ideational and ideomotor apraxias), preferentially one side (i.e., limb-kinetic apraxia) or, alternatively, interlimb coordination, as in the case of gait apraxia.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Roy, E.A. and Square, P.A. (1985) Common considerations in the study of limb, verbal, and oral apraxia, in Neuropsychological Studies of Apraxia and Related Disorders (Roy, E.A., ed.), Elsevier Science Publishers B.V., Amsterdam, The Netherlands, pp. 111–161.

    Google Scholar 

  2. De Renzi, E. (1989) Apraxia, in Handbook of Neuropsychology (Boller, F. and Grafman, J., eds.), Elsevier Science, Amsterdam, pp. 245–263.

    Google Scholar 

  3. Rothi, L.J. and Heilman, K.M. (eds.) (1997) Apraxia: the Neuropsychology of Action, Psychology Press, East Sussex, UK.

    Google Scholar 

  4. Leiguarda, R. and Marsden, C.D. (2000) Limb apraxias: higher-order disorders of sensorimotor integration [review]. Brain 123, 860–879.

    Article  PubMed  Google Scholar 

  5. Rebeiz, J.J., Kolodny, E.H., and Richardson, E.P. (1968) Corticodentatonigral degeneration with neuronal achromasia. Arch. Neurol. 18, 20–33.

    Article  PubMed  CAS  Google Scholar 

  6. Riley, D.E., Lang, A.E., Lewis, A., et al. (1990) Corticobasal ganglionic degeneration. Neurology 40, 1203–1212.

    Article  PubMed  CAS  Google Scholar 

  7. Gibb, W.R., Luthert, P.J., and Marsden, C.D. (1989) Corticobasal degeneration. Brain 112, 1171–1192.

    Article  PubMed  Google Scholar 

  8. Rinne, J., Lee, M., Thompson, P., and Marsden, C.D. (1994) Corticobasal degeneration: a clinical study of 36 cases. Brain 117, 1183–1196.

    Article  PubMed  Google Scholar 

  9. Leiguarda, R., Lees, A.J., Merello, M., Starkstein, S., and Marsden, C.D. (1994) The nature of apraxia in corticobasal degeneration. J. Neurol. Neurosurg. Psychiatry 57, 455–459.

    Article  PubMed  CAS  Google Scholar 

  10. Kampoliti, K., Goetz, C.G., Boeve, B.F., et al. (1998) Clinical presentation and pharmacological therapy in corticobasal degeneration. Arch. Neurol. 55, 957–961.

    Article  Google Scholar 

  11. Litvan, I., Agid, Y., Goetz, C., et al. (1997) Accuracy of the clinical diagnosis of corticobasal degeneration: a clinicopathologic study. Neurology 48, 119–125.

    Article  PubMed  CAS  Google Scholar 

  12. Edwards, D.F., Denel, R.K., Baum, C.M., and Morris, J.C. (1991) A quantitative analysis of apraxia in senile dementia of Alzheimer type: a stage-related differences in prevalence and type. Dementia 2, 142–149.

    Google Scholar 

  13. Luchelli, F., Lopez, O., Faglioni, P., and Boller, F. (1993) Ideomotor and ideational apraxias in Alzheimer’s disease. Int. J. Ger. Psych. 8, 413–417.

    Article  Google Scholar 

  14. Derousné, C., Lagha-Pierucci, S., Thibault, S., Bandouin-Madec, V., and Lacomblez, S. (2000) Apraxic disturbances in patients with mild to moderate Alzheimer’s disease. Neuropsychologia 38, 1760–1769.

    Article  Google Scholar 

  15. Leiguarda, R. and Starkstein, S. (1998) Apraxia in the syndromes of Pick Complex, in Pick’s Disease and Pick Complex (Kertesz, A. and Muññoz, D.G., eds.), Wiley-Liss. New York, pp. 129–143.

    Google Scholar 

  16. Leiguarda, R., Pramstaller, P., Merello, M., Starkstein, S., Lees, A.J., and Marsden, C.D. (1997) Apraxia in Parkinson’s disease, progressive supranuclear palsy, multiple system atrophy, and neuroleptic induced parkinsonism. Brain 120, 75–90.

    Article  PubMed  Google Scholar 

  17. Shelton, P.A. and Knopman, D.S. (1991) Ideomotor apraxia in Huntington’s disease. Arch. Neurol. 48, 35–41.

    Article  PubMed  CAS  Google Scholar 

  18. Liepmann, H. (1920) Apraxia. Ergeb Gesamten Medizin 1, 516–543.

    Google Scholar 

  19. Clark, M.A., Merians, A.S., Kothari, A., et al. (1994) Spatial planning deficits in limb apraxia. Brain 117, 1093–1106.

    Article  PubMed  Google Scholar 

  20. Poizner, H., Clark, M.A., Merians, A.S., Macauley, B., Gonzalez Rothi, L.J., and Heilman, K.M. (1995) Joint coordination deficits in limb apraxia. Brain 118, 227–242.

    Article  PubMed  Google Scholar 

  21. Leiguarda, R., Merello, M., and Balej, J. (2000) Apraxia in corticobasal degeneration, in Corticobasal Degeneration and Related Disorders. Advances in Neurology, vol. 82 (Litvan, I., Goetz, C.G., and Lang, A., eds.), Lippincott, Williams &Wilkins, Philadelphia, pp. 103–121.

    Google Scholar 

  22. Caselli, R.J., Stelmach, G.E., Caviness, J.V., et al. (1999) A kinematic study of progressive apraxia with and without dementia. Mov. Disord. 14, 276–287.

    Article  PubMed  CAS  Google Scholar 

  23. Haaland, K.Y. and Flaherty, D. (1984) The different types of limb apraxia errors made by patients with left vs. right hemisphere damage. Brain Cogn. 3, 370–384.

    Article  PubMed  CAS  Google Scholar 

  24. Rapcsak, S.Z., Ochipa, C., Beeson, P.M., and Rubens, A. (1993) Apraxia and the right hemisphere. Brain Cogn. 23, 181–202.

    Article  PubMed  CAS  Google Scholar 

  25. Rushworth, M.F.S., Nixon, P.D., Wade, D.T., Renowden, S., and Passingham, R.E. (1998) The left hemisphere and the selection of learned actions. Neuropsychologia 36, 11–24.

    Article  PubMed  CAS  Google Scholar 

  26. Ochipa, C., Rothi, L.J.G., and Heilman, K.M. (1992) Conceptual apraxia in Alzheimer’s Disease. Brain 115, 1061–1071.

    Article  PubMed  Google Scholar 

  27. De Renzi, E. and Lucchelli, F. (1988) Ideational apraxia. Brain 113, 1173–1188.

    Article  Google Scholar 

  28. Heilman, K.M., Maher, L.H., Greenwald, L., and Rothi, L.J. (1997) Conceptual apraxia from lateralized lesions. Neurology 49, 457–464.

    Article  PubMed  CAS  Google Scholar 

  29. Pramstaller, P.P. and Marsden, C.D. (1996) The basal ganglia and apraxia [review]. Brain 119, 319–340.

    Article  PubMed  Google Scholar 

  30. Leiguarda, R. (2001) Limb-apraxia: cortical or subcortical. Neuroimage 14, 5137–5141.

    Article  Google Scholar 

  31. Kleist, K. (1907) Kortikate (innervatorische) Apraxie. J. Psychiatr. Neurol. 25, 46–112.

    Google Scholar 

  32. Kleist, K. (1931) Gehirnpathologische und lokalisatorische Ergebnisse: das Stirnhirn im engeren Sinne und seine Störungen. Z. ges Neurol. und Psychiat. 131, 442–448.

    Article  Google Scholar 

  33. Faglioni, P. and Basso, A. (1985) Historical perspectives on neuroanatomical correlates of limb apraxia, in Neuropsychological Studies of Apraxia and Relates Disorders (Roy, E.A., ed.), Elsevier Science Publishers B.y., Amsterdam, The Netherlands, pp. 3–44.

    Google Scholar 

  34. Denes, G., Mantovan, M.C., Gallana, A., and Cappelletti, J.V. (1998) Limb-kinetic apraxia. Mov. Disord. 13, 468–476.

    Article  PubMed  CAS  Google Scholar 

  35. Blasi, V., Labruna, L., Soricelli, A., and Carlomagno, S. (1999) Limb-kinetic apraxia: a neuropsychological description. Neurocase 5, 201–211.

    Article  Google Scholar 

  36. Leiguarda, R., Merello, M., Nouzeilles, M.I., Balej, J., Rivero, A., and Nogués, M. (2001) Limb-kinetic apraxia: clinical and kinematic features. Mol. Disord., in press.

    Google Scholar 

  37. Jacobs, D.H., Adair, J.C., Macauley, B.L., Gold, M., Gonzalez Rothi, L.J., and Heilman, K..M. (1999) Apraxia in corticobasal degeneration. Brain Cogn. 40, 336–354.

    Article  PubMed  CAS  Google Scholar 

  38. Pillon, B., Blin, J., Vadailhet, M., et al. (1995) The neuropsychological pattern of corticobasal degeneration: comparison with supranuclear palsy and Alzheimer’s disease. Neurology 45, 1477–1483.

    Article  PubMed  CAS  Google Scholar 

  39. Blondel, A., Eustache, F., Schaeffer, S., Maire, R., Lechvalier B., and Sayette, V. (1997) Etudie clinique et cognitive de l’apraxie dans l’atrophie cortico-basale. Rev. Neurol. (Paris) 153, 737–747.

    CAS  Google Scholar 

  40. Graham, N.L., Zenan, A., Young, A.W., Patterson, K., and Hodges, J.R. (1999) Dyspraxia in a patient with corticobasal degeneration: the role of visual and tactile inputs to action. J. Neurol. Neurosurg. Psychiatry 67, 334–344.

    Article  PubMed  CAS  Google Scholar 

  41. Okuda, B., Tachibana, H., Kawabata, K., Takeda, M., and Sugita, M. (1992) Slowly progressive limb-kinetic apraxia with a decrease in unilateral cerebral blood flow. Acta Neurol. Scand. 86, 76–81.

    Article  PubMed  CAS  Google Scholar 

  42. Kertesz, A., Martínez-Lange, P., Davidson, W., and Mufloz, D.G. (2000) The corticobasal degeneration síndrome overlaps progressive aphasia and frontotemporal dementia. Neurology 14, 1368–1375.

    Article  Google Scholar 

  43. Ozsancak, C., Auzou, P., and Hannequin, D. (2000) Dysarthria and orofacial apraxia in corticobasal degeneration. Mov. Disord. 15, 905–910.

    Article  PubMed  CAS  Google Scholar 

  44. Sharpe, M.H., Cermak, S.A., and Sax, D.S. (1983) Motor planning in Parkinson patients. Neuropsychologia 21, 455–46’2.

    Article  PubMed  CAS  Google Scholar 

  45. Goldenberg, G., Wimmer, A., Auff, E., and Schnaberth, G. (1986) Impairment of motor planning in patients with Parkinson’s disease: evidence for ideomotor apraxia texting. J. Neurol. Neurosurg. Psychiatry 49, 1266–1272.

    Article  PubMed  CAS  Google Scholar 

  46. Grossman, M., Carbell, S., Gollomp, S., Stern, M.B., Bernon, G., and Hurtig, H.I. (1991) Sentence comprehension and praxis deficits in Parkinson’s disease. Neurology 41, 1620–1626.

    Article  PubMed  CAS  Google Scholar 

  47. Leiguarda, R., Merello, M., Balej, J., Starkstein, S., Nogués, M., and Marsden, C.D. (2000) Disruption of spatial organization and interjoint coordination in Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy. Mov. Disord. 15, 627–640.

    Article  PubMed  CAS  Google Scholar 

  48. Cambier, J., Masson, M., Viader, F., Limodin, J., and Strube, A. (1985) Le syndrome frontal de la paralysie supranucléaire progressive. Rev. Neurol. (Paris) 141, 528–536.

    CAS  Google Scholar 

  49. Collins Si., Ahlskog, J.E., Parisi, J.E., and Maraganore, D.M. (1995) Progressive supranuclear palsy: neuropathologically based diagnostic clinical criteria. J. Neurol. Neurosurg. Psychiatry 58, 167–173.

    Article  PubMed  CAS  Google Scholar 

  50. Bergeron, C., Pollamen, M.S., Weyer, L., and Lang, A.E. (1997) Cortical degeneration in progressive supranuclear palsy. A comparison with cortical-basal ganglionic degeneration. J. Neuropathol. Exp. Neurol. 56, 726–734.

    PubMed  CAS  Google Scholar 

  51. Jeannerod, M. (1966) Cortical coding of visual object attributes during object-oriented behaviour, in Vision and Movements Mechanisms in the Cerebral Cortex (Caminitti, R., Hoffmann, K.P., Lacquanti, F., and Altman, J., eds.), Human Frontier Science Program, Strasbourg, pp. 15–23.

    Google Scholar 

  52. Rizzolatti, G., Luppino, G., and Matelli, M. (1998) The organization of the cortical motor system: new concepts [review]. Electroencephalogr. Clin. Neurophysiol. 106, 283–296.

    Article  PubMed  CAS  Google Scholar 

  53. Burnod, Y., Baraduc, P., Battaglia, A., et al. (1999) Parieto-frontal coding of reaching: an integrated framework. Exp. Brain Res. 129, 325–346.

    Article  PubMed  CAS  Google Scholar 

  54. Jeannerod, M., Arbid, M.A., Rizzolatti, G., and Sakata, H. (1995) Grasping objects: the cortical mechanisms of visuomotor transformation. Trends Neurosci. 18, 314–320.

    Article  PubMed  CAS  Google Scholar 

  55. Rizzolatti, G., Camarda, R., Fogassi, M., Gentilucci, M., Luppino, G., and Matelli, M. (1988) Functional organization of inferior area 6 in the macaque monkey: II Area F5 and the control of distal movements. Exp. Brain Res. 71, 491–507.

    Article  PubMed  CAS  Google Scholar 

  56. Pandya, D. and Kuypers, H.G. (1969) Cortico-cortical connections in the rhesus monkeys. Brain Res. 13, 13–36.

    Article  PubMed  CAS  Google Scholar 

  57. Sakata, H., Taira, M., Mine, S., and Murata, A. (1992) Hand-movements related neurons of the posterior parietal cortex of the monkey: their role in visual guidance of hand movements, in Control of Arm Movements in Space: Neurophysiological and Computational Approaches (Caminiti, R., Johnson, P.B., and Burnod, Y., eds.), Springer, Berlin, pp. 185–198.

    Chapter  Google Scholar 

  58. Binkofski, F., Buccino, G., Posse, S., Seitz, R.J., Rizzolatti, G., and Freund, H.J. (1999) A fronto-parietal circuit for object manipulation in man: evidence from an fMRI study. Eur. J. Neurosci. 11, 3276–3286.

    Article  PubMed  CAS  Google Scholar 

  59. Alexander, G.E., DeLong, M.R., and Strick, P.L. (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann. Rev. Neurosci. 9, 357–381.

    Article  PubMed  CAS  Google Scholar 

  60. Yeterian, E.H. and Pandya, D.N. (1993) Striatal connections of the parietal association cortices in rhesus monkeys. J. Comp. Neurol. 332, 175–197.

    Article  PubMed  CAS  Google Scholar 

  61. Dickson, D.W., Liu, W.K., Reding, H.K., and Yen, S.H. (2000) Neuropathologic and molecular considerations, in Corticobasal Degeneration and Related Disorders. Advances in Neurology, vol. 82 (Litvan, I., Goetz, C.G., and Lang, A.E., eds.), Lippincott, Williams & Wilkins, Philadelphia, pp. 9–28.

    Google Scholar 

  62. Brooks, D.J. (2000) Functional imaging studies in corticobasal degeneration, in Corticobasal Degeneration and Related Disorders. Advances in Neurology, vol. 82 (Litvan, I., Goetz, C.G., and Lang, A.E., eds.), Lippincott, Williams & Wilkins, Philadelphia, pp. 209–216.

    Google Scholar 

  63. Daniel, S.E., de Bruin, V., and Lees, A.J. (1995) The clinical and pathological spectrum of Steele-RichardsonOlszewski syndrome (progressive supranuclear palsy): a reappraises [review]. Brain 118, 759–770.

    Article  PubMed  Google Scholar 

  64. Rinne, J., Portin, R., Ruottinen, H., et al. (2000) Cognitive impairment and the brain dopaminergic system in Parkinson disease. Arch. Neurol. 57, 470–475.

    Article  PubMed  CAS  Google Scholar 

  65. Hu, M.T.M., Taylor-Robinson, S.D., Ray Chaudhuri, K., et al. (1999). Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study. J. Neurol. Neurosurg. Psychiatry 67, 20–26.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Leiguarda, R. (2003). Distinctive Features of Apraxia in Corticobasal Degeneration and Other Neurological Illnesses. In: Bédard, MA., Agid, Y., Chouinard, S., Fahn, S., Korczyn, A.D., Lespérance, P. (eds) Mental and Behavioral Dysfunction in Movement Disorders. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-326-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-326-2_10

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-372-5

  • Online ISBN: 978-1-59259-326-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics