Chemoradiotherapy in Muscle-Invasive Bladder Cancer

  • Bruce J. Roth
Part of the Cancer Drug Discovery and Development book series (CDD&D)


Transitional cell carcinoma of the bladder is diagnosed in approx 50,000 individuals in the United States each year, and accounts for 10,000 deaths annually. A majority of patients will present with nonmuscle-invasive disease, be treated adequately with transurethral resection (TURBT) with or without intravesical chemotherapy or immunotherapy, and will have only a 10–15% risk (higher for higher grades) of developing muscle-invasive disease. In contradistinction, the natural history of muscle-invasive disease is much more aggressive, with a 5-yr survival of only 50%.


Bladder Cancer Clin Oncol Radical Cystectomy Transitional Cell Carcinoma Invasive Bladder Cancer 
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© Springer Science+Business Media New York 2003

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  • Bruce J. Roth

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