Chemoradiation in Therapy for Colon and Rectum Carcinoma

  • Jason H. Lee
  • Christopher G. Willett
Part of the Cancer Drug Discovery and Development book series (CDD&D)


Chemotherapy and radiation therapy play an important role in the management of colorectal carcinoma. Significant improvements in tumor control and overall survival have been demonstrated with the use of combined-modality therapy in several randomized clinical trials performed over the past 25 yr. This chapter reviews the role of adjuvant chemotherapy and radiation therapy for colon and rectal cancer. Issues surrounding chemoradiation for rectal cancer, including sphincter preservation, total mesorectal excision, local excision, and newer chemotherapy agents, are also discussed.


Rectal Cancer Clin Oncol Total Mesorectal Excision Local Excision Radiat Oncol Biol Phys 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Jason H. Lee
  • Christopher G. Willett

There are no affiliations available

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