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Chemoradiation in Therapy for Colon and Rectum Carcinoma

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Chemoradiation in Cancer Therapy

Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

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Abstract

Chemotherapy and radiation therapy play an important role in the management of colorectal carcinoma. Significant improvements in tumor control and overall survival have been demonstrated with the use of combined-modality therapy in several randomized clinical trials performed over the past 25 yr. This chapter reviews the role of adjuvant chemotherapy and radiation therapy for colon and rectal cancer. Issues surrounding chemoradiation for rectal cancer, including sphincter preservation, total mesorectal excision, local excision, and newer chemotherapy agents, are also discussed.

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Authors
  1. Jason H. Lee MD
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  2. Christopher G. Willett MD
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Editors and Affiliations

  1. Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

    Hak Choy MD

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Lee, J.H., Willett, C.G. (2003). Chemoradiation in Therapy for Colon and Rectum Carcinoma. In: Choy, H. (eds) Chemoradiation in Cancer Therapy. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-325-5_14

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  • DOI: https://doi.org/10.1007/978-1-59259-325-5_14

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-313-8

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