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The Hippocampus

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Neural Mechanisms of Anesthesia

Part of the book series: Contemporary Clinical Neuroscience ((CCNE))

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Abstract

The hippocampus has been used for studies of anesthetic mechanisms of action for at least twenty years, and has been better studied than any other brain region in this regard. This is because hippocampal cortex is anatomically quite simple, and it is relatively easy to access this brain region in vivo. It is especially well suited for brain slice experiments because several important synaptic connections can be preserved in thin sections. Much has been learned about how various anesthetics alter hippocampal function, and much of this appears to be generalizable to other brain areas.

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Authors
  1. M. Bruce MacIver
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Editors and Affiliations

  1. Department of Anesthesiology, University of California at Davis School of Medicine, Davis, CA, USA

    Joseph F. Antognini MD

  2. Department of Neurobiology, Physiology and Behavior, University of California at Davis School of Medicine, Davis, CA, USA

    Earl Carstens PhD

  3. Department of Anesthesia and Critical Care, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

    Douglas E. Raines MD

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MacIver, M.B. (2003). The Hippocampus. In: Antognini, J.F., Carstens, E., Raines, D.E. (eds) Neural Mechanisms of Anesthesia. Contemporary Clinical Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-322-4_9

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  • DOI: https://doi.org/10.1007/978-1-59259-322-4_9

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