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Anesthesia, the Spinal Cord and Motor Responses to Noxious Stimulation

  • Chapter
Neural Mechanisms of Anesthesia

Part of the book series: Contemporary Clinical Neuroscience ((CCNE))

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Abstract

The spinal cord has emerged as an important site of anesthetic action. For many decades, studies that examined the effects of anesthetics on spinal cord function had unknown impact, since it was unclear what clinical endpoint might be affected by such action. For example, when an anesthetic depresses spinal dorsal horn neuronal responses to tactile stimulation, what endpoint is achieved? Because the movement response that accompanies noxious stimulation is ablated in large part via a spinal cord action of anesthetics (1–3), there is renewed interest in the effects of anesthetics on the spinal cord.

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Authors
  1. Joseph F. Antognini
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  2. Earl Carstens
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Editors and Affiliations

  1. Department of Anesthesiology, University of California at Davis School of Medicine, Davis, CA, USA

    Joseph F. Antognini MD

  2. Department of Neurobiology, Physiology and Behavior, University of California at Davis School of Medicine, Davis, CA, USA

    Earl Carstens PhD

  3. Department of Anesthesia and Critical Care, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

    Douglas E. Raines MD

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© 2003 Springer Science+Business Media New York

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Antognini, J.F., Carstens, E. (2003). Anesthesia, the Spinal Cord and Motor Responses to Noxious Stimulation. In: Antognini, J.F., Carstens, E., Raines, D.E. (eds) Neural Mechanisms of Anesthesia. Contemporary Clinical Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-322-4_11

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  • DOI: https://doi.org/10.1007/978-1-59259-322-4_11

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-294-0

  • Online ISBN: 978-1-59259-322-4

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