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Abstract

Neurologic complications are relatively common in patients with leukemia. They occur either as a result of direct dissemination of leukemia to the nervous system, or indirectly as a consequence of treatment. Leukemic cells usually infiltrate the leptomeninges, but rarely the brain parenchyma and peripheral nerves may be affected. Neurologic complications may also result from treatment-related neurotoxicity or bone marrow aplasia. This chapter focuses principally on the direct neurologic complications of leukemia, particularly leptomeningeal disease.

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Haaxma-Reiche, H. (2003). Leukemia. In: Schiff, D., Wen, P.Y. (eds) Cancer Neurology in Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-317-0_24

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  • DOI: https://doi.org/10.1007/978-1-59259-317-0_24

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