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Signal Transduction Networks

Ras as a Paradigm

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Oncogene-Directed Therapies

Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

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Abstract

Research in signal transduction has changed radically in recent years. Attention has shifted from functions of individual proteins to relationships between proteins and pathways. As pathways have been elucidated, it has become evident that these pathways form complex interactive networks, in which boundaries between pathways become blurred. This chapter discusses some of the implications of this emerging view in terms of understanding the biology and also the prospects for therapy based on signaling networks.

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Authors
  1. Frank McCormick PhD
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Editors and Affiliations

  1. Henderson Research Centre, Department of Medicine, McMaster University, Hamilton, Ontario, Canada

    Janusz Rak MD, PhD

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© 2003 Humana Press Inc., Totowa, NJ

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McCormick, F. (2003). Signal Transduction Networks. In: Rak, J. (eds) Oncogene-Directed Therapies. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-313-2_3

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  • DOI: https://doi.org/10.1007/978-1-59259-313-2_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9738-0

  • Online ISBN: 978-1-59259-313-2

  • eBook Packages: Springer Book Archive

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