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The Role of Neuropsychological Evaluation in the Neurosurgical Treatment of Movement Disorders

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Surgical Treatment of Parkinson’s Disease and Other Movement Disorders

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Patients with Parkinson’s disease (PD) and their physicians have become increasingly accustomed to treatments having few, if any, or reversible side effects (1). Given the concern about the potential neurobehavioral morbidity associated with movement disorders surgery, particularly in instances of bilateral and ablative surgery, it is important to address neurobehavioral functioning and quality of life outcomes. Consistent with the clinical focus of this volume, this chapter does not delve into the role that movement disorders surgery might have in testing current models of the neurocognitive functions of the basal ganglia (for reviews of this issue see Middleton and Strick [2,3]). We focus on neuropsychological evaluation and outcomes in neurosurgery for PD, but also mention the limited literature pertaining to surgery for movement disorders of other conditions (e.g., multiple sclerosis, essential tremor).

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References

  1. Benabid, A. L., Pollak, P., Seigneuret, E., Hoffmann, D., Gay, E., and Perret, J. (1993) Chronic VIM thalamic stimulation in Parkinson’s disease, essential tremor and extra-pyramidal dyskinesias. Acta Neurochir. Suppl. 58, 39–44.

    CAS  Google Scholar 

  2. Middleton, F. A. and Strick, P. L. (2000) Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res. Rev. 31, 236–250.

    Article  PubMed  CAS  Google Scholar 

  3. Middleton, F. A. and Strick, P. L. (2000) Basal ganglia output and cognition: evidence from anatomical, behavioral, and clinical studies. Brain Cogn. 42, 183–200.

    Article  PubMed  CAS  Google Scholar 

  4. Guridi, J. and Lozano, A. M. (1997) A brief history of pallidotomy. Neurosurgery 41, 1169–1180.

    Article  PubMed  CAS  Google Scholar 

  5. Ostertag, C. B., Lücking, C. H., Mehdorn, H. M., and Deuschl, G. (1997) Stereotaktische Behandlung der Bewegungstörungen. Nervenarzt 68, 477–484.

    Article  PubMed  CAS  Google Scholar 

  6. Siegfried, J. and Blond, S. (1997) The Neurosurgical Treatment of Parkinson’s Disease and Other Movement Disorders. Williams & Wilkins Europe Ltd., London.

    Google Scholar 

  7. Gabriel, E. M. and Nashold, B. S. Jr. (1998) Evolution of neuroablative surgery for involuntary movement disorders: an historical review. Neurosurgery 42, 575–590.

    Article  PubMed  CAS  Google Scholar 

  8. Gildenberg, P. L. (1998) The history of surgery for movement disorders. Neurosurg. Clin. North Am. 9, 283–294.

    CAS  Google Scholar 

  9. Speelman, J. D. and Bosch, D. A. (1998) Resurgence of functional neurosurgery for Parkinson’s disease: a historical perspective. Mov. Disord. 13, 582–588.

    Article  PubMed  CAS  Google Scholar 

  10. Gildenberg, P. L. (2000) History of movement disorder surgery. In: Movement Disorder Surgery, Progress in Neurological Surgery, vol. 15 (Lozano, A. M., ed.), Karger, Basel, pp. 1–20.

    Google Scholar 

  11. Gross, C. E., Boraud, T., Guehl, D., Bioulac, B., and Bezard, E. (1999) From experimentation to the surgical treatment of Parkinson’s disease: prelude or suite in basal ganglia research? Prog. Neurobiol. 59, 509–532.

    Article  PubMed  CAS  Google Scholar 

  12. Riklan, M. and Levita, E. (1969) Subcortical Correlates of Human Behavior: A Psychological Study of Basal Ganglia and Thalamic Surgery. Williams and Wilkins, Baltimore, MD.

    Google Scholar 

  13. Shapiro, D. Y., Sadowsky, D. A., Henderson, W. G., and Van Buren, J. M. (1973) An assessment of cognitive function in postthalamotomy Parkinson patients. Confin. Neurol. 35, 144–166.

    Article  PubMed  CAS  Google Scholar 

  14. Van Buren, J. M., Li, C. L., Shapiro, D. Y., Henderson, W. G., and Sadowsky, D. A. (1973) A qualitative and quantitative evaluation of parkinsonians three to six years following thalamotomy. Confin. Neurol. 35, 202–235.

    Article  PubMed  Google Scholar 

  15. Jurko, M. F. and Andy, O. J. (1964) Psychological aspects of diencephalotomy. J. Neurol. Neurosurg. Psychiatry 27, 516–521.

    Article  PubMed  CAS  Google Scholar 

  16. Jurko, M. F. and Andy, O. J. (1973) Psychological changes correlated with thalamotomy site. J. Neurol. Neurosurg. Psychiatry 36, 846–852.

    Article  PubMed  CAS  Google Scholar 

  17. Johnson, M. D. and Ojemann, G. A. (2000) The role of the human thalamus in language and memory: evidence from electrophysiological studies. Brain Cogn. 42, 218–230.

    Article  PubMed  CAS  Google Scholar 

  18. Almgren, P. E., Andersson, A. L., and Kullberg, G. (1969) Differences in verbally expressed cognition following left and right ventrolateral thalamotomy. Scand. J. Psychol. 10, 243–249.

    Article  PubMed  CAS  Google Scholar 

  19. Almgren, P. E., Andersson, A. L., and Kullberg, G. (1972) Long-term effects on verbally expressed cognition following left and right ventrolateral thalamotomy. Confin. Neurol. 34, 162–168.

    Article  Google Scholar 

  20. Asso, D., Crown, S., Russell, J. A., and Logue, V. (1969) Psychological aspects of the stereotactic treatment of Parkinsonism. Br. J. Psychiatry 115, 541–553.

    Article  PubMed  CAS  Google Scholar 

  21. Christensen, A. L., Juul-Jensen, P., Malmros, R., and Harmsen, A. (1970) Psychological evaluation of intelligence and personality in parkinsonism before and after stereotaxic surgery. Acta Neurol. Scand. 46, 527–537.

    Article  PubMed  CAS  Google Scholar 

  22. Fünfgeld, E. W. (1967) Psychopathologie und Klinik des Parkinsonismus vor und nach stereotaktischen Operationen. Springer Verlag, Berlin.

    Book  Google Scholar 

  23. McFie, J. (1960) Psychological effects of stereotaxic operations for the relief of parkinsonian symptoms. J. Ment. Sci. 106, 1512–1517.

    PubMed  CAS  Google Scholar 

  24. Vilkki, J. and Laitinen, L. V. (1974) Differential effects of left and right ventrolateral thalamotomy on receptive and expressive verbal performances and face-matching. Neuropsychologia 12, 11–19.

    Article  PubMed  CAS  Google Scholar 

  25. Vilkki, J. and Laitinen, L. V. (1976) Effects of pulvinotomy and ventrolateral thalamotomy on some cognitive functions. Neuropsychologia 14, 67–78.

    Article  PubMed  CAS  Google Scholar 

  26. Wilkinson, S. B. and Tröster, A. I. (1998) Surgical interventions in neurodegenerative disease: impact on memory and cognition. In: Memory in Neurodegenerative Disease: Biological, Cognitive, and Clinical Perspectives (Tröster, A. I., ed.), Cambridge University Press, Cambridge, UK, pp. 362–376.

    Chapter  Google Scholar 

  27. Levita, E., Riklan, M., and Cooper, I. S. (1964) Verbal and perceptual functions after surgery of subcortical structures. Percept. Mot. Skills 18, 195–202.

    Article  PubMed  CAS  Google Scholar 

  28. Koller, W., and Hristova, A. (1996) Efficacy and safety of stereotaxic surgical treatment of tremor disorders. Eur. J. Neurol. 3, 507–514.

    Article  Google Scholar 

  29. Laitinen, L. V. (2000) Behavioral complications of early pallidotomy. Brain Cogn. 42, 313–323.

    Article  PubMed  CAS  Google Scholar 

  30. Bronstein, J. M., DeSalles, A., and DeLong, M. R. (1999) Stereotactic pallidotomy in the treatment of Parkinson disease: an expert opinion. Arch. Neurol. 56, 1064–1069.

    Article  PubMed  CAS  Google Scholar 

  31. Defer, G.-L., Widner, H., Marié, R.-M., Rémy, P., and Levivier, M. (1999) Core assessment program for surgical interventional therapies in Parkinson’s disease (CAPSIT-PD). Mov. Disord. 14, 572–584.

    Article  PubMed  CAS  Google Scholar 

  32. Hallett, M. and Litvan, I. (1999) Evaluation of surgery for Parkinson’s disease: a report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 53, 1910–1921.

    Article  PubMed  CAS  Google Scholar 

  33. Fields, J. A. and Tröster, A. I. (2000) Cognitive outcomes after deep brain stimulation for Parkinson’s disease: a review of initial studies and recommendations for future research. Brain Cogn. 42, 268–293.

    Article  PubMed  CAS  Google Scholar 

  34. Perozzo, P., Rizzone, M., Bergamasco, B., Castelli, L., Lanotte, M., Tavella, A., et al. (2001) Deep brain stimulation of subthalamic nucleus: behavioural modifications and familiar relations. Neurol. Sci. 22, 81–82.

    Article  PubMed  CAS  Google Scholar 

  35. Aarsland, D., Larsen, J. P., Karlsen, K., Lim, N. G., and Tandberg, E. (1999) Mental symptoms in Parkinson’s disease are important contributors to caregiver distress. Int. J. Geriatr. Psychiatry 14, 866–874.

    Article  PubMed  CAS  Google Scholar 

  36. Morrison, C. E., Borod, J. C., Brin, M. F., Raskin, S. A., Germano, I. M., Weisz, D. J., and Olanow, C. W. (2000) A program for neuropsychological investigation of deep brain stimulation (PNIDBS) in movement disorder patients: development, feasibility, and preliminary data. Neuropsychiatry Neuropsychol. Behav. Neurol. 13, 204–219.

    PubMed  CAS  Google Scholar 

  37. Saint-Cyr, J. A. and Trépanier, L. L. (2000) Neuropsychologic assessment of patients for movement disorder surgery. Mov. Disord. 15, 771–783.

    Article  PubMed  CAS  Google Scholar 

  38. Tröster, A. I., Woods, S. P., Fields, J. A., Lyons, K. E., Pahwa, R., Higginson, C. I., and Koller, W. C. (2002) Neuropsychological deficits in essential tremor: an expression of cerebello-thalamo-cortical pathophysiology? Eur. J. Neurol. 9, 143–151.

    Article  PubMed  Google Scholar 

  39. Owen, A. M., Sahakian, B. J., Hodges, J. R., Summers, B. A., Polkey, C. E., and Robbins, T. W. (1995) Dopaminedependent fronto-striatal planning deficits in early Parkinson’s disease. Neuropsychology 9, 126–140.

    Article  Google Scholar 

  40. Tröster, A. I., Fields, J. A., and Koller, W. C. (2000) Parkinson’s disease and parkinsonism. In: Textbook of Geriatric Neuropsychiatry (Coffey, C. E. and Cummings, J. L., eds.), American Psychiatric Press, Washington, DC, pp. 559–600.

    Google Scholar 

  41. Trépanier, L. L., Saint-Cyr, J. A., Lozano, A. M., and Lang, A. E. (1998) Neuropsychological consequences of posteroventral pallidotomy for the treatment of Parkinson’s disease. Neurology 51, 207–215.

    Article  Google Scholar 

  42. Stebbins, G. T., Gabrieli, J. D., Shannon, K. M., Penn, R. D., and Goetz, C. G. (2000) Impaired frontostriatal cognitive functioning following posteroventral pallidotomy in advanced Parkinson’s disease. Brain Cogn. 42, 348–363.

    Article  PubMed  CAS  Google Scholar 

  43. Dymek, M. P., Atchison, P., Harrell, L., and Marson, D. C. (2001) Competency to consent to medical treatment in cognitively impaired patients with Parkinson’s disease. Neurology 56, 17–24.

    Article  PubMed  CAS  Google Scholar 

  44. Cahn, D. A., Sullivan, E. V., Shear, P. K., Pfefferbaum, A., Heit, G., and Silverberg, G. (1998) Differential contributions of cognitive and motor component processes to physical and instrumental activities of daily living in Parkinson’s disease. Arch. Clin. Neuropsychology 13, 575–583.

    CAS  Google Scholar 

  45. Tröster, A. I., Fields, J. A., Straits-Tröster, A. I., Lyons, K. E., Higginson, C. I., Chmidling, S., et al. (2000) Executive function, coping, mood state, and quality of life in Parkinson’s disease patients being evaluated for pallidotomy [abstract]. J. Int. Neuropsychol. Soc. 6, 207.

    Google Scholar 

  46. Jacobs, D. M., Marder, K., Cote, L. J., Sano, M., Stern, Y., and Mayeux, R. (1995) Neuropsychological characteristics of oreclinical dementia in Parkinson’s disease. Neurology 45, 1691–1696.

    Article  PubMed  CAS  Google Scholar 

  47. Mahieux, F., Fenelon, G., Flahault, A., Manifacier, M. J., Michelet, D., and Boller, F. (1998) Neuropsychological prediction of dementia in Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 64, 178–183.

    Article  PubMed  CAS  Google Scholar 

  48. Buytenhuijs, E. L., Berger, H. J., Van Spaendonck, K. P., Horstink, M. W., Borm, G. F., and Cools, A. R. (1994) Memory and learning strategies in patients with Parkinson’s disease. Neuropsychologia 32, 335–342.

    Article  PubMed  CAS  Google Scholar 

  49. Tröster, A. I. and Fields, J. A. (1995) Frontal cognitive function and memory in Parkinson’s disease: toward a distinction between prospective and declarative memory impairments? Behav. Neurol. 8, 59–74.

    Google Scholar 

  50. Huber, S. J., Shuttleworth, E. C., and Paulson, G. W. (1986) Dementia in Parkinson’s disease. Arch. Neurol. 43, 987–990.

    Article  PubMed  CAS  Google Scholar 

  51. Tröster, A. I., Stalp, L. D., Paolo, A. M., Fields, J. A., and Koller, W. C. (1995) Neuropsychological impairment in Parkinson’s disease with and without depression. Arch. Neurol. 52, 1164–1169.

    Article  PubMed  Google Scholar 

  52. Tröster, A. I., Paolo, A. M., Lyons, K. E., Glatt, S. L., Hubble, J. P., and Koller, W. C. (1995) The influence of depression on cognition in Parkinson’s disease: a pattern of impairment distinguishable from Alzheimer’s disease. Neurology 45, 672–676.

    Article  PubMed  Google Scholar 

  53. Kuzis, G., Sabe, L., Tiberti, C., Leiguarda, R., and Starkstein, S. E. (1997) Cognitive functions in major depression and Parkinson disease. Arch. Neurol. 54, 982–986.

    Article  PubMed  CAS  Google Scholar 

  54. Stern, Y., Marder, K., Tang, M. X., and Mayeux, R. (1993) Antecedent clinical features associated with dementia in Parkinson’s disease. Neurology 43, 1690–1692.

    Article  PubMed  CAS  Google Scholar 

  55. Burchiel, K. J., Taha, J. M., and Favre, J. (1997) Posteroventral pallidotomy for Parkinson’s disease patients. In: Neurosurgical Operative Atlas, vol. 6 (Rengachary, S. S. and Wilkins, R. H., eds.), Am. Assoc. of Neurol. Surgeons, Park Ridge, II, pp. 13–26.

    Google Scholar 

  56. Bejjani, B. P., Damier, P., Arnulf, I., Thivard, L., Bonnet, A. M., Dormont, D., et al. (1999) Transient acute depression induced by high-frequency deep-brain stimulation. N. Engl. J. Med. 340, 1476–1480.

    Article  PubMed  CAS  Google Scholar 

  57. Durif, F., Lemaire, J.-J., Debilly, B., and Dordain, G. (1999) Acute and chronic effects of anteromedial globus pallidus stimulation in Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 67, 315–322.

    Article  PubMed  CAS  Google Scholar 

  58. Lauterbach, E. C., Jackson, J. G., Wilson, A. N., Dever, G. E., and Kirsh, A. D. (1997) Major depression after left posterior globus pallidus lesions. Neuropsychiatry Neuropsychol. Behay. Neurol. 10, 9–16.

    CAS  Google Scholar 

  59. Melnick, M. E., Dowling, G. A., Aminoff, M. J., and Barbaro, N. M. (1999) Effect of pallidotomy on postural control and motor function in Parkinson disease. Arch. Neurol. 56, 1361–1365.

    Article  PubMed  CAS  Google Scholar 

  60. Higginson, C. I., Fields, J. A., Koller, W. C., and Tröster, A. I. (2001) Questionnaire assessment potentially overestimates anxiety in Parkinson’s disease. J. Clin. Psychol. Med. Set. 8, 95–99.

    Article  Google Scholar 

  61. Saint-Cyr, J. A. and Trépanier, L. L. (2000) Neuropsychological considerations in movement disorder surgery. In: Movement Disorder Surgery, Progress in Neurological Surgery, vol. 15 (Lozano, A. M., ed.), Karger, Basel, pp. 266–271.

    Google Scholar 

  62. Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., and Gornbein, J. (1994) The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44, 2308–2314.

    Article  PubMed  CAS  Google Scholar 

  63. Grace, J., Stout, J. C., and Malloy, P. F. (1999) Assessing frontal lobe behavioral syndromes with the frontal lobe personality scale. Assessment 6, 269–284.

    Article  PubMed  CAS  Google Scholar 

  64. Narabayashi, H., Miyashita, N., Hattori, Y., Saito, K., and Endo, K. (1997) Posteroventral pallidotomy: its effect on motor symptoms and scores of MMPI test in patients with Parkinson’s disease. Park. Rel. Disord. 3, 7–20.

    Article  CAS  Google Scholar 

  65. Diller, L., Riklan, M., and Cooper, I. S. (1956) Preoperative response to stress as a criterion of the response to neurosurgery in Parkinson’s disease. J. Am. Geriatr. Soc. 4, 1301–1308.

    PubMed  Google Scholar 

  66. Tröster, A. I., Lyons, K. E., and Straits-Tröster, K. A. (1999) Determinants of health-related quality of life changes in Parkinson’s disease. In: Quality of Life in Parkinson’s Disease (Martínez-Martín, P. and Koller, W. C., eds.), Masson. Barcelona. pp. 55–77.

    Google Scholar 

  67. Tröster, A. I., Fields, J. A., Straits-Tröster, K. A., Lyons, K. E., Miyawaki, E., Wilkinson, S. B., et al. (1998) Motoric and psychosocial correlates of quality of life in Parkinson’s disease four months after unilateral pallidotomy [abstract]. Neurology 50(Suppl. 4), A299.

    Google Scholar 

  68. Tröster, A. I. (2000) Clinical neuropsychology, functional neurosurgery, and restorative neurology in the next millennium: beyond secondary outcome measures. Brain Cogn. 42, 117–119.

    Article  Google Scholar 

  69. Tomaszewski, K. J. and Holloway, R. G. (2001) Deep brain stimulation in the treatment of Parkinson’s disease: a cost- effectiveness analysis. Neurology 57, 663–671.

    Article  PubMed  CAS  Google Scholar 

  70. Hailey, D. and Harstall, C. (1998) Posteroventral pallidotomy for Parkinson’s disease: assessment and policy on a technology in transition. Health Policy 43, 55–64.

    Article  PubMed  CAS  Google Scholar 

  71. Thompson, P. D. (2001) Deep brain stimulation is superior to ablative surgery for Parkinson’s disease: the case against. J. Clin. Neurosci. 8, 291–292; discussion 293–294.

    Article  PubMed  CAS  Google Scholar 

  72. López-Lozano, J. J. and Mata, M. (1999) Surgical treatment for Parkinson’s disease: impact on the patient’s quality of life. In: Quality of Life in Parkinson’s Disease (Martínez-Martín, P. and Koller, W. C., eds.), Masson, Barcelona, pp. 107–136.

    Google Scholar 

  73. Laing, R. J. (2000) Measuring outcome in neurosurgery [editorial]. Br. J. Neurosurg. 14, 181–184.

    Article  PubMed  CAS  Google Scholar 

  74. Iacopino, D. G., Lucerna, S., Giller, C. A., Salpietro, F. M., Lo Presti, R., Sessa, E., et al. (1998) Pallidotomy improves quality of life in selected parkinsonian patients: an Italian report. Funct. Neurol. 13, 105–115.

    PubMed  CAS  Google Scholar 

  75. Lange, K. W., Robbins, T. W., Marsden, C. D., James, M., Owen, A. M., and Paul, G. M. (1992) Ldopa withdrawal in Parkinson’s disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction. Psychopharmacology 107, 394–404.

    Article  PubMed  CAS  Google Scholar 

  76. Alegret, M., Vendrell, P., Junqué, C., Valldeoriola, F., Nobbe, F. A., Rumià, J., and Tolosa, E. (2000) Effects of unilateral posteroventral pallidotomy on `on-off’ cognitive fluctuations in Parkinson’s disease. Neuropsychologia 38, 628–633.

    Article  PubMed  CAS  Google Scholar 

  77. Green, J. and Barnhart, H. (2000) The impact of lesion laterality on neuropsychological change following posterior pallidotomy: a review of current findings. Brain Cogn. 42, 379–398.

    Article  PubMed  CAS  Google Scholar 

  78. York, M. K., Levin, H. S., Grossman, R. G., and Hamilton, W. J. (1999) Neuropsychological outcome following unilateral pallidotomy. Brain 122, 2209–2220.

    Article  PubMed  Google Scholar 

  79. Schmand, B., de Bie, R. M., Koning-Haanstra, M., de Smet, J. S., Speelman, J. D., and van Zomeren, A. H. (2000) Unilateral pallidotomy in PD: a controlled study of cognitive and behavioral effects. The Netherlands Pallidotomy Study (NEPAS) group. Neurology 54, 1058–1064.

    Article  PubMed  CAS  Google Scholar 

  80. Spiegel, E., Wycis, H., Orchinik, C., and Freed, H. (1955) Thalamic chronotaraxis. Arch. Neurol. Psychiatry 73, 469–471.

    Google Scholar 

  81. Niebuhr, H. Jr. (1962) Some psychological aspects of patients with Parkinson’s disease before and after ventrolateral thalamotomy. In: Stereoencephalotomy. Part II Clinical and Physiological Applications, vol. Il (Spiegel, E. A. and Wycis, H. T., eds.), Grune and Stratton, New York, pp. 349–357.

    Google Scholar 

  82. Burchiel, K. J. (1995) Thalamotomy for movement disorders. Neurosurg. Clin. North Am. 6, 55–71.

    CAS  Google Scholar 

  83. Fünfgeld, E. W. (1961) Die psychischen Hirnfunktionen bei hirnatrophischen Zustandsbildern nach operativer Belastung (stereotaktische Hirnoperationen älterer Parkinsonpatienten). Acta Neurochir. (Wien) 7(Suppl.), 539–544.

    Google Scholar 

  84. Riklan, M., Diller, L., Weiner, H., and Cooper, I. S. (1960) Psychological studies on effects of chemosurgery of the basal ganglia in parkinsonism. I. Intellectual functioning. Arch. Gen. Psychiatry 2, 22–31.

    Article  Google Scholar 

  85. Krayenbühl, H., Wyss, O. A. M., and Yasargil, M. G. (1961) Bilateral thalamotomy and pallidotomy as treatment for bilateral parkinsonism. J. Neurosurg. 18, 429–444.

    Article  PubMed  Google Scholar 

  86. Ojemann, G. A., Hoyenga, K. B., and Ward, A. A. Jr. (1971) Prediction of short-term verbal memory disturbance after ventrolateral thalamotomy. J. Neurosurg. 35, 203–210.

    Article  PubMed  CAS  Google Scholar 

  87. Kocher, U., Siegfried, J., and Perret, E. (1982) Verbal and nonverbal learning ability of Parkinson patients before and after unilateral ventrolateral thalamotomy. Appl. Neurophysiol. 45, 311–316.

    PubMed  CAS  Google Scholar 

  88. RikIan, M., Levita, E., and Cooper, I. S. (1966) Psychological effects of bilateral subcortical surgery for Parkinson’s disease. J. Nerv. Ment. Dis. 141, 403–409.

    Google Scholar 

  89. Perret, E. and Siegfried, J. (1968) Memory and learning performance of Parkinson patients before and after thalamotomy. In: Third Symposium on Parkinson’s Disease (Gillingham, F. J. and Donaldson, I. M. L., eds.), E. & S. Livingstone Ltd., Edinburgh, UK, pp. 164–168.

    Google Scholar 

  90. Krayenbühl, H., Siegfried, J., Kohenof, M., and Yasargil, M. G. (1965) Is there a dominant thalamus? Confin. Neurol. 26, 246–249.

    PubMed  Google Scholar 

  91. Hays, P., Krikler, B., Walsh, L. S., and Woolfson, G. (1966) Psychological changes following surgical treatment of parkinsonism. Am. J. Psychiatry 123, 657–663.

    PubMed  CAS  Google Scholar 

  92. RikIan, M., Diller, L., and Weiner, H. (1960) Psychological studies on the effects of chemosurgery of the basal ganglia in parkinsonism. II. Aspects of personality. Arch. Gen. Psychiatry 3, 267–275.

    Article  Google Scholar 

  93. Choppy, M., Zimbacca, N., and le Beau, J. (1973) Psychological changes after selective frontal surgery (especially cingulotomy) and after stereotactic surgery of the basal ganglia. In: Surgical Approaches in Psychiatry (Laitinen, L. V. and Livingston, K. E., eds.), Medical and Technical Publishing, Lancaster, UK, pp. 175–181.

    Google Scholar 

  94. Riklan, M. and Levita, E. (1970) Psychological studies of thalamic lesions in humans. J. Nerv. Ment. Dis. 150, 251–265.

    Article  PubMed  CAS  Google Scholar 

  95. Riklan, M., Levita, E., Zimmerman, J., and Cooper, I. S. (1969) Thalamic correlates of language and speech. J. Neurol. Sci. 8, 307–328.

    Article  PubMed  CAS  Google Scholar 

  96. Rikian, M. and Cooper, I. S. (1975) Psychometric studies of verbal functions following thalamic lesions in humans. Brain Lang. 2, 45–64.

    Article  Google Scholar 

  97. Bell, D. S. (1968) Speech functions of the thalamus inferred from the effects of thalamotomy. Brain 91, 619–638.

    Article  PubMed  CAS  Google Scholar 

  98. Petrovici, J. N. (1980) Speech disturbances following stereotaxic surgery in ventrolateral thalamus. Neurosurg. Rev. 3, 189–195.

    Article  PubMed  CAS  Google Scholar 

  99. Samra, K., Riklan, M., Levita, E., Zimmerman, J., Waltz, J. M., Bergmann, L., and Cooper, I. S. (1969) Language and speech correlates of anatomically verified lesions in thalamic surgery for parkinsonism. J. Speech. Hear. Res. 12, 510–540.

    PubMed  CAS  Google Scholar 

  100. Quaglieri, C. E. and Celesia, G. G. (1977) Effect of thalamotomy and levodopa therapy on the speech of Parkinson patients. Eur. Neurol. 15, 34–39.

    Article  PubMed  CAS  Google Scholar 

  101. Lund-Johansen, M., Hugdahl, K., and Wester, K.(1996) Cognitive function in patients with Parkinson’s disease undergoing stereotaxic thalamotomy. J. Neurol. Neurosurg. Psychiatry 60, 564–571.

    Article  PubMed  CAS  Google Scholar 

  102. Fukuda, M., Kameyama, S., Yoshino, M., Tanaka, R., and Narabayashi, H. (2000) Neuropsychological outcome following pallidotomy and thalamotomy for Parkinson’s disease. Stereotact. Funct. Neurosurg. 74, 11–20.

    Article  PubMed  CAS  Google Scholar 

  103. Broggi, G., Dones, I., Ferroli, P., Franzini, A., Genitrini, S., and Micon, B. M. (2001) Surgery for movement disorders: complications and complication avoidance. Semin. Neurosurg. 12, 225–231.

    Article  Google Scholar 

  104. Young, R. F. (2001) Gamma knife treatment for movement disorders. Semin. Neurosurg. 12, 233–243.

    Article  Google Scholar 

  105. Magnin, M., Jeanmonod, D., Morel, A., and Siegemund, M. (2001) Surgical control of the human thalamocortical dysrhythmia: II. Pallidothalamic tractotomy in Parkinson’s disease. Thalamus Rel. Sys. 1, 81–89.

    Google Scholar 

  106. Schuurman, P. R., Bosch, D. A., Bossuyt, P. M., Bonsel, G. J., van Someren, E. J., de Bie, R. M., et al. (2000) A comparison of continuous thalamic stimulation and thalamotomy for suppression of severe tremor. N. Engl. J. Med. 342, 461–468.

    Article  PubMed  CAS  Google Scholar 

  107. Angelini, L., Bono, R., Broggi, G., et al. (1979) Psychological implications of stereotactic thalamotomies for cerebral palsy. Ital. J. Neurol. Sci. 1, 32–36.

    Google Scholar 

  108. Angelini, L., Nardocci, N., Bono, R., and Broggi, G. (1982) Depression after stereotactic thalamotomy in patients with abnormal movements. Ital. J. Neurol. Sci. 3, 301–310.

    Article  PubMed  CAS  Google Scholar 

  109. Müller, V. C. and Yasargil, M. G. (1959) Zur Psychiatrie der stereotaktischen Hirnoperationen bei extrapyramidalen Erkrankungen. Schweiz. Arch. Neurol. Neurochirurgie Psychiatrie 84, 136–154.

    Google Scholar 

  110. Jurko, M. F. and Andy, O. J. (1961) Electrical and behavioral changes following thalamotomy. Surg. Forum 12, 404–406.

    PubMed  CAS  Google Scholar 

  111. Pahwa, R., Lyons, K. E., Wilkinson, S. B., Tröster, A. I., Overman, J., Kieltyka, J., and Koller, W. C. (2001) Comparison of thalamotomy to deep brain stimulation of the thalamus in essential tremor. Mov. Disord. 16, 140–143.

    Article  PubMed  CAS  Google Scholar 

  112. Blumetti, A. E. and Modesti, L. M. (1980) Long term cognitive effects of stereotactic thalamotomy on non-parkin.sonian dyskinetic patients. Appl. Neurophysiol. 43, 259–262.

    PubMed  CAS  Google Scholar 

  113. Mohadjer, M., Goerke, H., Milios, E., Etou, A., and Mundinger, F. (1990) Long-term results of stereotaxy in the treatment of essential tremor. Stereotact. Funct. Neurosurg. 55, 125–129.

    Article  Google Scholar 

  114. Goldman, M. S. and Kelly, P. J. (1992) Symptomatic and functional outcome of stereotactic ventralis lateralis thalamotomy for intention tremor. J. Neurosurg. 77, 223–229.

    Article  PubMed  CAS  Google Scholar 

  115. Goldman, M. S., Ahlskog, J. E., and Kelly, P. J. (1992) The symptomatic and functional outcome of stereotactic thalamotomy for medically intractable essential tremor. J. Neurosurg. 76, 924–928.

    Article  PubMed  CAS  Google Scholar 

  116. Jankovic, J., Cardoso, F., Grossman, R. G., and Hamilton, W. J. (1995) Outcome after stereotactic thalamotomy for parkinsonian, essential, and other types of tremor. Neurosurgery 37, 680–686.

    Article  PubMed  CAS  Google Scholar 

  117. Shahzadi, S., Tasker, R. R., and Lozano, A. (1995) Thalamotomy for essential and cerebellar tremor. Stereotact. Funct. Neurosurg. 65, 11–17.

    Article  PubMed  CAS  Google Scholar 

  118. Critchley, G. R. and Richardson, P. L. (1998) Vim thalamotomy for the relief of the intention tremor of multiple sclerosis. Br. J. Neurosurg. 12, 559–562.

    Article  PubMed  CAS  Google Scholar 

  119. Rossitch, E. Jr., Zeidman, S. M., Nashold, B. S. Jr., Homer, J., Walker, J., Osborne, D., and Bullard, D. E. (1988) Evaluation of memory and language function pre- and postthalamotomy with an attempt to define those patients at risk for postoperative dysfunction. Surg. Neurol. 29, 11–16.

    Article  PubMed  Google Scholar 

  120. Whittle, I. R. and Haddow, L. J. (1995) CT guided thalamotomy for movement disorders in multiple sclerosis: problems and paradoxes. Acta Neurochir. Suppl. 64, 13–16.

    Article  PubMed  CAS  Google Scholar 

  121. Spiegel, E. A., Wycis, H. T., Szekely, E. G., Adams, J., Flanagan, M., and Baird, H. W., III (1963) Campotomy in various extrapyramidal disorders. J. Neurosurg. 20, 870–884.

    Google Scholar 

  122. Andy, O. J., Jurko, M. F., and Sias, F. R. Jr. (1963) Subthalamotomy in treatment of parkinsonian tremor. J. Neurosurg. 20, 861–871.

    Google Scholar 

  123. Mundinger, F. (1968) Results of 500 subthalamotomies in the region of the zona incerta. In: Third Symposium on Parkinson’s Disease (Gillingham, F. J. and Donaldson, I. M. L., eds.), E. & S. Livingstone Ltd., Edinburgh, UK, pp. 261–265.

    Google Scholar 

  124. McCarter, R. J., Walton, N. H., Rowan, A. F., Gill, S. S., and Palomo, M. (2000) Cognitive functioning after subthalamic nucleotomy for refractory Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 69, 60–66.

    Article  CAS  Google Scholar 

  125. Svennilson, E., Torvik, A., Lowe, R., and Leksell, L. (1960) Treatment of Parkinsonism by stereotactic thermolesions in the pallidal region: a clinical evaluation of 83 cases. Acta Psych. Neurol. Scand. 35, 358–377.

    Article  CAS  Google Scholar 

  126. Alkhani, A. and Lozano, A. M. (2001) Pallidotomy for parkinson disease: a review of contemporary literature. J. Neurosurg. 94, 43–49.

    Article  PubMed  CAS  Google Scholar 

  127. Riordan, H. J., Flashman, L. A., and Roberts, D. W. (1997) Neurocognitive and psychosocial correlates of ventroposterolateral pallidotomy surgery in Parkinson’s disease [electronic manuscript]. Neurosurg. Focus 2(3), Manuscript 7.

    Article  Google Scholar 

  128. Cahn, D. A., Sullivan, E. V., Shear, P. K., Heit, G., Lim, K. O., Marsh, L., et al.(1998) Neuropsychological and motor functioning after unilateral anatomically guided posterior ventral pallidotomy. Preoperative performance and three-month follow-up. Neuropsychiatry Neuropsychol. Behay. Neurol. 11, 136–145.

    CAS  Google Scholar 

  129. Masterman, D., DeSalles, A., Baloh, R. W., Frysinger, R., Foti, D., Behnke, E., et al. (1998) Motor, cognitive, and behavioral performance following unilateral ventroposterior pallidotomy for Parkinson disease. Arch. Neurol. 55, 1201–1208.

    Article  PubMed  CAS  Google Scholar 

  130. Scott, R., Gregory, R., Hines, N., Carroll, C., Hyman, N., Papanasstasiou, V., et al. (1998) Neuropsychological, neurological and functional outcome following pallidotomy for Parkinson’s disease. A consecutive series of eight simultaneous bilateral and twelve unilateral procedures. Brain 121, 659–675.

    Article  PubMed  Google Scholar 

  131. Tröster, A. I., Fields, J. A., Wilkinson, S. B., and Koller, W. C. (1998) Neurobehavioral outcome of left and right pallidotomy for Parkinson’s disease [abstract]. Clin. Neuropsychologist 12, 268–269.

    Google Scholar 

  132. Yokoyama, T., Imamura, Y., Sugiyama, K., Nishizawa, S., Yokota, N., Ohta, S., and Uemura, K. (1999) Prefrontal dysfunction following unilateral posteroventral pallidotomy in Parkinson’s disease. J. Neurosurg. 90, 1005–1010.

    Article  PubMed  CAS  Google Scholar 

  133. Dewey, R. B. Jr., Giller, C. A., Broline, S. K., Mendelsohn, D. B., Lacritz, L. H., and Cullum, C. M. (2000) Clinical outcome of unilateral stereotactic pallidotomy without microelectroe recording for intractable Parkinson’s disease. Park. Rel. Disord. 6, 7–16.

    Article  Google Scholar 

  134. Kubu, C. S., Grace, G. M., and Parrent, A. G. (2000) Cognitive outcome following pallidotomy: the influence of side of surgery and age of patient at disease onset. J. Neurosurg. 92, 384–389.

    Article  PubMed  CAS  Google Scholar 

  135. Lacritz, L. H., Cullum, C. M., Frol, A. B., Dewey, R. B. Jr., and Giller, C. A. (2000) Neuropsychological outcome following unilateral stereotactic pallidotomy in intractable Parkinson’s disease. Brain Cogn. 42, 364–378.

    Article  PubMed  CAS  Google Scholar 

  136. Rettig, G. M., York, M. K., Lai, E. C., Jankovic, J., Krauss, J. K., Grossman, R. G., and Levin, H. S. (2000) Neuropsychological outcome after unilateral pallidotomy for the treatment of Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 69, 326–336.

    Article  PubMed  CAS  Google Scholar 

  137. Trépanier, L. L., Kumar, R., Lozano, A. M., Lang, A. E., and Saint-Cyr, J. A. (2000) Neuropsychological outcome of GPi pallidotomy and GPi or STN deep brain stimulation in Parkinson’s disease. Brain Cogn. 42, 324–347.

    Article  PubMed  Google Scholar 

  138. Intemann, P. M., Masterman, D., Subramanian, I., DeSalles, A., Behnke, E., Frysinger, R., and Bronstein, J. M. (2001) Staged bilateral pallidotomy for treatment of Parkinson disease. J. Neurosurg. 94, 437–444.

    Article  PubMed  CAS  Google Scholar 

  139. Soukup, V. M., Ingram, F., Schiess, M. C., Bonnen, J. G., Nauta, H. J., and Calverley, J. R. (1997) Cognitive sequelae of unilateral posteroventral pallidotomy. Arch. Neurol. 54, 947–950.

    Article  PubMed  CAS  Google Scholar 

  140. Perrine, K., Dogali, M., Fazzini, E., Sterio, D., Kolodny, E., Eidelberg, D., et al. (1998) Cognitive functioning after pallidotomy for refractory Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 65, 150–154.

    Article  PubMed  CAS  Google Scholar 

  141. Kuzis, G., Sabe, L., Tiberti, C., Dorrego, F., and Starkstein, S. (2001) Neuropsychological effects of pallidotomy in patients with Parkinson’s disease [letter]. J. Neurol. Neurosurg. Psychiatry 71, 563.

    Article  PubMed  CAS  Google Scholar 

  142. Schulz, G. M., Peterson, T., Sapienza, C. M., Greer, M., and Friedman, W. (1999) Voice and speech characteristics of persons with Parkinson’s disease pre- and post-pallidotomy surgery: preliminary findings. J. Speech Lang. Hear. Res. 42, 1176–1194.

    PubMed  CAS  Google Scholar 

  143. Legg, C. F. and Sonnenberg, B. R. (1998) Changes in aspects of speech and language functioning following unilateral pallidotomy. Aphasiology 12, 257–266.

    Article  Google Scholar 

  144. Tröster, A. I., Fields, J. A., Hanisch, C., and Beatty, W. W. (1999) Clustering and switching on semantic verbal fluency in Parkinson’s disease after unilateral, microelectrode-guided pallidotomy [abstract]. J. Int. Neuropsychol. Soc. 5, 273.

    Google Scholar 

  145. Obwegeser, A. A., Uitti, R. J., Lucas, J. A., Witte, R. J., Turk, M. F., and Wharen, R. E. Jr. (2000) Predictors of neuropsychological outcome in patients following microelectrode-guided pallidotomy for Parkinson’s disease. J. Neurosurg. 93, 410–420.

    Article  PubMed  CAS  Google Scholar 

  146. Van Horn, G., Hassenbusch, S. J., Zouridakis, G., Mullani, N. A., Wilde, M. C., and Papanicolaou, A. C. (2001) Pallidotomy: a comparison of responders and nonresponders. Neurosurgery 48, 263–271; discussion 271–273.

    PubMed  Google Scholar 

  147. Lombardi, W. J., Gross, R. E., Trépanier, L. L., Lang, A. E., Lozano, A. M., and Saint-Cyr, J. A. (2000) Relationship of lesion location to cognitive outcome following microelectrode-guided pallidotomy for Parkinson’s disease: support for the existence of cognitive circuits in the human pallidum. Brain 123, 746–758.

    Article  PubMed  Google Scholar 

  148. Yokochi, F., Okiyama, R., Taniguchi, M., Takahashi, H., Hasegawa, N., and Hamada, I. (2001) Relationship between lesion location and the outcome of pallidotomy for Parkinson’s disease. J. Neurol. 248(Suppl. 3), 32–36.

    Article  Google Scholar 

  149. Burns, J. M., Wilkinson, S., Kieltyka, J., Overman, J., Lundsgaarde, T., Tollefson, T., et al. (1997) Analysis of pallidotomy lesion positions using three-dimensional reconstruction of pallidal lesions, the basal ganglia, and the optic tract. Neurosurgery 41, 1303–1316.

    Article  PubMed  CAS  Google Scholar 

  150. Hariz, M. I. (1990) Correlation between clinical outcome and size and site of the lesion in computed tomography guided thalamotomy and pallidotomy. Stereotact. Funct. Neurosurg. 55, 172–185.

    Article  Google Scholar 

  151. Krauss, J. K., Desaloms, J. M., Lai, E. C., King, D. E., Jankovic, J., and Grossman, R. G. (1997) Microelectrodeguided posteroventral pallidotomy for treatment of Parkinson’s disease: postoperative magnetic resonance imaging analysis. J. Neurosurg. 87, 358–367.

    Article  PubMed  CAS  Google Scholar 

  152. Goodman, S. H., Wilkinson, S., Overman, J., Koller, W. C., Tröster, A., Pahwa, R., et al. (1998) Lesion volume and clinical outcome in stereotactic pallidotomy and thalamotomy. Stereotact. Funct. Neurosurg. 71, 164–172.

    Article  PubMed  CAS  Google Scholar 

  153. Shannon, K. M., Penn, R. D., Kroin, J. S., Adler, C. H., Janko, K. A., York, M., and Cox, S. J. (1998) Stereotactic pallidotomy for the treatment of Parkinson’s disease. Efficacy and adverse effects at 6 months in 26 patients. Neurology 50, 434–438.

    Article  PubMed  CAS  Google Scholar 

  154. Crowe, S. F., O’Sullivan, J. D., Peppard, R. F., McNeill, P. M., Bardenhagen, F., and Bowden, S. (1998) Lett posteroventral pallidotomy results in a deficit in verbal memory. Behay. Neurol. 11, 79–84.

    Google Scholar 

  155. Rettig, G. M., Lai, E. C., Krauss, J. K., Grossman, R. G., and Jankovic, J. (1998) Neuropsychological evaluation of patients with Parkinson’s disease before and after pallidal surgery. In: Pallidal Surgery for the Treatment of Parkinson’s Disease and Movement Disorders (Krauss, J. K., Grossman, R. G., and Jankovic, J., eds.), Lippincott-Raven, Philadelphia, PA, pp. 211–231.

    Google Scholar 

  156. Peppard, R. F., and Crowe, S. F. (1999) Cognitive changes due to neurosurgical ablative and stimulating procedures in PD patients. In: Mental Dysfunction in Parkinson’s Disease II, vol. 11 (Wolters, E. C., Scheltens, P., and Berendse, H. W., eds.), Academic Pharmaceutical Productions, Utrecht, The Netherlands, pp. 177–188.

    Google Scholar 

  157. Alterman, R. L., Kelly, P., Sterio, D., Fazzini, E., Eidelberg, D., Perrine, K., and Beric, A. (1997) Selection criteria for unilateral posteroventral pallidotomy. Acta Neurochir. Suppl. 68, 18–23.

    PubMed  CAS  Google Scholar 

  158. Iacono, R. P., Carlson, J. D., Kuniyoshi, S., Mohamed, A., Meltzer, C., and Yamada, S. (1997) Contemporaneous bilateral pallidotomy [electronic manuscript]. Neurosurg. Focus 2(3), Manuscript 5.

    Article  Google Scholar 

  159. Ghika, J., Ghika-Schmid, F., Fankhauser, H., Assal, G., Vingerhoets, F., Albanese, A., et al.(1999) Bilateral contemporaneous posteroventral pallidotomy for the treatment of Parkinson’s disease: neuropsychological and neurological side effects. Report of four cases and review of the literature. J. Neurosurg. 91, 313–321.

    Google Scholar 

  160. Gálvez-Jiménez, N., Lozano, A., Tasker, R., Duff, J., Hutchison, W., and Lang, A. E. (1998) Pallidal stimulation in Parkinson’s disease patients with a prior unilateral pallidotomy. Can. J. Neurol. Sci. 25, 300–305.

    PubMed  Google Scholar 

  161. Bezerra, M. L. S., Martinez, J.-V. L., and Nasser, J. A. (1999) Transient acute depresssion induced by high-frequency deep-brain stimulation [correspondence]. N. Engl. J. Med. 341, 1003–1004.

    Article  PubMed  CAS  Google Scholar 

  162. Martínez-Martín, P., Valldeoriola, F., Molinuevo, J. L., Nobbe, F. A., Rumia, J., and Tolosa, E. (2000) Pallidotomy and quality of life in patients with Parkinson’s disease: an early study. Mov. Disord. 15, 65–70.

    Article  PubMed  Google Scholar 

  163. Straits-Tröster, K., Fields, J. A., Wilkinson, S. B., Pahwa, R., Lyons, K. E., Koller, W. C., and Tröster, A. I. (2000) Health-related quality of life in Parkinson’s disease after pallidotomy and deep brain stimulation. Brain Cogn. 42, 399–416.

    Article  Google Scholar 

  164. Baron, M. S., Vitek, J. L., Bakay, R. A., Green, J., Kaneoke, Y., Hashimoto, T., et al. (1996) Treatment of advanced Parkinson’s disease by posterior GPi pallidotomy: 1-year results of a pilot study. Ann. Neurol. 40, 355–366.

    Article  PubMed  CAS  Google Scholar 

  165. Uitti, R. J., Wharen, R. E., Duffy, J. R., Lucas, J. A., Schneider, S. L., Rippeth, J. D., et al. (2000) Unilateral pallidotomy for Parkinson’s disease: speech, motor, and neuropsychological outcome measurements. Park. Rel. Disord. 6, 133–143.

    Article  Google Scholar 

  166. Junqué, C., Alegret, M., Nobbe, F. A., Valldeoriola, F., Pueyo, R., Vendrell, P., et al. (1999) Cognitive and behavioral changes after unilateral posteroventral pallidotomy: relationship with lesional data from MRI. Mov. Disord. 14, 780–789.

    Article  PubMed  Google Scholar 

  167. D’ Antonio, L. L., Zimmerman, G. J., and Iacono, R. P. (2000) Changes in health related quality of life in patients with Parkinson’s disease with and without posteroventral pallidotomy. Acta Neurochir. 142, 759–767.

    Article  Google Scholar 

  168. Blond, S., Caparros-Lefebvre, D., Parker, F., Assaker, R., Petit, H., Guieu, J.-D., and Christiaens, J.-L. (1992) Control of tremor and involuntary movement disorders by chronic stereotactic stimulation of the ventral intermediate thalamic nucleus. J. Neurosurg. 77, 62–68.

    Article  PubMed  CAS  Google Scholar 

  169. Caparros-Lefebvre, D., Blond, S., Pécheux, N., Pasquier, F., and Petit, H. (1992) Evaluation neuropsychologique avant et après stimulation thalamiaue chez 9 parkinsoniens. Rev. Neurol. 148, 117–122.

    PubMed  CAS  Google Scholar 

  170. Tröster, A. I., Fields, J. A., Wilkinson, S. B., Busenbark, K., Miyawaki, E., Overman, J., et al. (1997) Neuropsychological functioning before and after unilateral thalamic stimulating electrode implantation in Parkinson’s disease [electronic manuscript]. Neurosurg. Focus 2(3) , Article 9.

    Google Scholar 

  171. Woods, S. P., Fields, J. A., Lyons, K. E., Koller, W. C., Wilkinson, S. B., Pahwa, R., and Tröster, A. I. (2001) Neuropsychological and quality of life changes following unilateral thalamic deep brain stimulation in Parkinson’s disease: a 12-month follow-up. Acta Neurochir. 143, 1273–1278.

    Article  CAS  Google Scholar 

  172. Tröster, A. I. (2000) Introduction to neurobehavioral issues in the neurosurgical treatment of movement disorders: basic issues, thalamotomy, and nonablative treatments. Brain Cogn. 42, 173–182.

    Article  Google Scholar 

  173. Hugdahl, K. and Wester, K. (1997) Lateralized thalamic stimulation: effects on verbal memory. Neuropsychiatry Neuropsychol. Behav. Neurol. 10, 155–161.

    PubMed  CAS  Google Scholar 

  174. Wester, K. and Hugdahl, K. (1997) Thalamotomy and thalamic stimulation: effects on cognition. Stereotact. Funct. Neurosurg. 69, 80–85.

    Article  PubMed  CAS  Google Scholar 

  175. Hugdahl, K. and Wester, K. (2000) Neurocognitive correlates of stereotactic thalamotomy and thalamic stimulation in Parkinsonian patients. Brain Cogn. 42, 231–252.

    Article  PubMed  CAS  Google Scholar 

  176. Tröster, A. I., Wilkinson, S. B., Fields, J. A., Miyawaki, K., and Koller, W. C. (1998) Chronic electrical stimulation of the left ventrointermediate (Vim) thalamic nucleus for the treatment of pharmacotherapy-resistant Parkinson’s disease: a differential impact on access to semantic and enisodic memory? Brain Cogn. 38, 125–149.

    Article  PubMed  Google Scholar 

  177. Lyons, K. E., Pahwa, R., Tröster, A. I., and Koller, W. C. (1997) A comparison of Parkinson’s disease symptoms and self-reported functioning and well-being. Park. Rel. Disord. 3, 207–209.

    Article  CAS  Google Scholar 

  178. Tröster, A. I., Fields, J. A., Pahwa, R., Wilkinson, S. B., Straits -Tröster, K. A., Lyons, K., et al. (1999) Neuropsychological and quality of life outcome after thalamic stimulation for essential tremor. Neurology 53, 1774–1780.

    Article  PubMed  Google Scholar 

  179. Lucas, J. A., Rippeth, J. D., Uitti, R. J., Shuster, E. A., and Wharen, R. E. (2000) Neuropsychological functioning in a patient with essential tremor with and without bilateral VIM stimulation Brain Cnn 42, 253–967

    Article  CAS  Google Scholar 

  180. Montgomery, E. B. Jr., Baker, K. B., Kinkel, R. P., and Barnett, G. (1999) Chronic thalamic stimulation for the tremor of multiple sclerosis. Neurology 53, 625–628.

    Article  PubMed  Google Scholar 

  181. Cooper, I. S., Upton, A. R., and Amin, I. (1980) Reversibility of chronic neurologic deficits. Some effects of electrical stimulation of the thalamus and internal cansule in man Annl Npurnnhysiol. 43, 244–258

    CAS  Google Scholar 

  182. Andy, O. J. (1983) Thalamic stimulation for control of movement disorders. Annl. Neuronhysinl. 46, 107–111

    CAS  Google Scholar 

  183. Brice, J. and McLellan, L. (1980) Suppression of intention tremor by contingent deep-brain stimulation. Lancet 1, 1221–1222.

    Article  PubMed  CAS  Google Scholar 

  184. Tröster, A. I., Fields, J. A., Wilkinson, S. B., Pahwa, R., Miyawaki, E., Lyons, K. E., and Koller, W. C. (1997) Unilateral pallidal stimulation for Parkinson’s disease: neurobehavioral functioning before and 3 months after electrode implantation. Neurology 49, 1078–1083.

    Article  PubMed  Google Scholar 

  185. Vingerhoets, G., van der Linden, C., Lannoo, E., Vandewalle, V., Caemaert, J., Wolters, M., and Van den Abbeele, D. (1999) Cognitive outcome after unilateral pallidal stimulation in Parkinson’s disease. J. Neurol. Neurosurg. Psychiatry 66, 297–304.

    Article  PubMed  CAS  Google Scholar 

  186. Merello, M., Nouzeilles, M. I., Kuzis, G., Cammarota, A., Sabe, L., Betti, O., et al. (1999) Unilateral radiofrequency lesion versus electrostimulation of posteroventral pallidum: a prospective randomized comparison. Mov. Disord. 14, 50–56.

    Article  PubMed  CAS  Google Scholar 

  187. Ardouin, C., Pillon, B., Peiffer, E., Bejjani, P., Limousin, P., Damier, P., et al. (1999) Bilateral subthalamic or pallidal stimulation for Parkinson’s disease affects neither memory nor executive functions: a consecutive series of 62 patients. Ann. Neurol. 46, 217–223.

    Article  PubMed  CAS  Google Scholar 

  188. Pillon, B., Ardouin, C., Damier, P., Krack, P., Houeto, J. L., Klinger, H., et al. (2000) Neuropsychological changes between “off” and “on” STN or GPi stimulation in Parkinson’s disease. Neurology. 55, 411–418.

    Article  PubMed  CAS  Google Scholar 

  189. Ghika, J., Villemure, J. G., Fankhauser, H., Favre, J., Assai, G., and Ghika-Schmid, F.(1998) Efficiency and safety of bilateral contemporaneous pallidal stimulation (deep brain stimulation) in levodopa-responsive patients with Parkinson’s disease with severe motor fluctuations: a 2-year follow-up review. J. Neurosurg. 89, 713–718.

    Article  PubMed  CAS  Google Scholar 

  190. Fields, J. A., Tröster, A. I., Wilkinson, S. B., Pahwa, R., and Koller, W. C. (1999) Cognitive outcome following staged bilateral pallidal stimulation for the treatment of Parkinson’s disease. Clin. Neurol. Neurosurg. 101, 182–188.

    Article  PubMed  CAS  Google Scholar 

  191. Dujardin, K., Krystkowiak, P., Defebvre, L., Blond, S., and Destee, A. (2000) A case of severe dysexecutive syndrome consecutive to chronic bilateral pallidal stimulation. Neuropsychologia 38, 1305–1315.

    Article  PubMed  CAS  Google Scholar 

  192. Fields, J. A., Tröster, A. I., Wilkinson, S. B., Lyons, K. E., Miyawaki, E., Pahwa, R., and Koller, W. C. (1998) Comparison of the cognitive safety of unilateral pallidal stimulation and pallidotomy [abstract]. Neurology 50(Suppl. 4), A389.

    Google Scholar 

  193. Vingerhoets, G., Lannoo, E., van der Linden, C., Caemaert, J., Vandewalle, V., van den Abbeele, D., and Wolters, M. (1999) Changes in quality of life following unilateral pallidal stimulation in Parkinson’s disease. J. Psychosom. Res. 46, 247–255.

    Article  PubMed  CAS  Google Scholar 

  194. Miyawaki, E., Perlmutter, J. S., Tröster, A. I., Videen, T. O., and Koller, W. C. (2000) The behavioral complications of pallidal stimulation: a case report. Brain Cogn. 42, 417–434.

    Article  PubMed  CAS  Google Scholar 

  195. Higginson, C. I., Fields, J. A., and Tröster, A. I. (2001) Which symptoms of anxiety diminish after surgical interventions for Parkinson’s disease? Neuropsychiatry Neuropsychol. Behav. Neurol. 14, 117–121.

    PubMed  CAS  Google Scholar 

  196. Moro, E., Scerrati, M., Romito, L. M., Roselli, R., Tonali, P., and Albanese, A. (1999) Chronic subthalamic nucleus stimulation reduces medication requirements in Parkinson’s disease. Neurology 53, 85–90.

    Article  PubMed  CAS  Google Scholar 

  197. Tröster, A. I., Fields, J. A., and Higginson, C. I. (2000) Near-term cognitive and mood state outcomes after bilateral subthalamic stimulation for Parkinson’s disease [abstract]. J. Int. Neuropsychol. Soc. 6, 392–393.

    Google Scholar 

  198. Lopiano, L., Rizzone, M., Bergamasco, B., Tavella, A., Torre, E., Perozzo, P., et al. (2001) Deep brain stimulation of the subthalamic nucleus: Clinical effectiveness and safety. Neurology 56, 552–554.

    Article  PubMed  CAS  Google Scholar 

  199. Lopiano, L., Rizzone, M., Perozzo, P., Tavella, A., Tone, E., Lanotte, M., and Bergamasco, B. (2001) Deep brain stimulation of the subthalamic nucleus: selection of patients and clinical results. Neurol. Sci. 22, 67–68.

    Article  PubMed  CAS  Google Scholar 

  200. Volkmann, J., Allert, N., Voges, J., Weiss, P. H., Freund, H.-J., and Sturm, V. (2001) Safety and efficacy of pallidal or subthalamic nucleus stimulation in advanced PD. Neurology 56, 548–551.

    Article  PubMed  CAS  Google Scholar 

  201. Jahanshahi, M., Ardouin, C. M., Brown, R. G., Rothwell, J. C., Obeso, J., Albanese, A., et al. (2000) The impact of deep brain stimulation on executive function in Parkinson’s disease. Brain 123, 1142–1154.

    Article  PubMed  Google Scholar 

  202. Gerschlager, W., Alesch, F., Cunnington, R., Deecke, L., Dirnberger, G., Endl, W., et al. (1999) Bilateral subthalamic nucleus stimulation improves frontal cortex function in Parkinson’s disease. An electrophysiological study of the contingent negative variation. Brain 122, 2365–2373.

    Article  PubMed  Google Scholar 

  203. Gerschlager, W., Bloem, B. R., Alesch, F., Lang, W., Deecke, L., and Cunnington, R. (2001) Bilateral subthalamic nucleus stimulation does not improve prolonged P300 latencies in Parkinson’s disease. J. Neurol. 248, 285–289.

    Article  PubMed  CAS  Google Scholar 

  204. Saint-Cyr, J. A., Trépanier, L. L., Kumar, R., Lozano, A. M., and Lang, A. E. (2000) Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson’s disease. Brain 123, 2091–2108.

    Article  PubMed  Google Scholar 

  205. Alegret, M., Junqué, C., Valldeoriola, F., Vendrell, P., Pilleri, M., Rumià, J., and Tolosa, E. (2001) Effects of bilateral subthalamic stimulation on cognitive function in Parkinson disease. Arch. Neurol. 58, 1223–1227.

    Article  PubMed  CAS  Google Scholar 

  206. Dujardin, K., Defebvre, L., Krystkowiak, P., Blond, S., and Destée, A. (2001) Influence of chronic bilateral stimulation of the subthalamic nucleus on cognitive function in Parkinson’s disease. J. Neurol. 248, 603–611.

    Article  PubMed  CAS  Google Scholar 

  207. Dromey, C., Kumar, R., Lang, A. E., and Lozano, A. M. (2000) An investigation of the effects of subthalarnic nucleus stimulation on acoustic measures of voice. Mov. Disord. 15, 1132–1138.

    Article  PubMed  CAS  Google Scholar 

  208. Gentil, M., Chauvin, P., Pinto, S., Pollak, P., and Benabid, A. L. (2001) Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian voice. Brain Lang. 78, 233–240.

    Article  PubMed  CAS  Google Scholar 

  209. Hariz, M. I., Johansson, F., Shamsgovara, P., Johansson, E., Hariz, G. M., and Fagerlund, M. (2000) Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: persistent improvement in mobility but increased dependency: a case study. Mov. Disord. 15, 136–139.

    Article  PubMed  CAS  Google Scholar 

  210. Benabid, A. I., Koudsié, A., Benazzouz, A., Hoffmann, D., Fraix, V., Chabardes, S., et al. (1999) Neurosurgical therapy in Parkinson’s disease. In: Mental Dysfunction in Parkinson’s Disease II, vol. 11 (Wolters, E. C., Scheltens, P., and Berendse, H. W., eds.), Academic Pharmaceutical Productions, Utrecht, The Netherlands, pp. 131–139.

    Google Scholar 

  211. Kumar, R., Lozano, A. M., Sime, E., Halket, E., and Lang, A. E. (1999) Comparative effects of unilateral and bilateral subthalarmic nucleus deep brain stimulation. Neurology 53, 561–566.

    Article  PubMed  CAS  Google Scholar 

  212. Benabid, A. L., Koudsié, A., Benazzouz, A., Vercueil, L., Fraix, V., Chabardes, S., et al. (2001) Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson’s disease. Extension to new indications such as dystonia and epilepsy. J. Neurol. 248(Suppl. 3) , 37–47.

    Article  Google Scholar 

  213. Houeto, J. L., Damier, P., Bejjani, P. B., Staedler, C., Bonnet, A. M., Arnulf, I., et al. (2000) Subthalamic stimulation in Parkinson disease: a multidisciplinary approach. Arch. Neurol. 57, 461–465.

    Article  PubMed  CAS  Google Scholar 

  214. Capus, L., Melatini, A., Zorzon, M., Torre, P., Carraro, N., Moretti, D., et al. (2001) Chronic bilateral electrical stimulation of the subthalamic nucleus for the treatment of advanced Parkinson’s disease. Neurol. Sci. 22, 57–58.

    Article  PubMed  CAS  Google Scholar 

  215. Ostrosky-Solis, F., Quintanar, L., Madrazo, I., Drucker-Colin, R., Franco-Bourland, R., and Leon-Meza, V. (1988) Neuropsychological effects of brain autograft of adrenal medullary tissue for the treatment of Parkinson’s disease. Neurology 38, 1442–1450.

    Article  PubMed  CAS  Google Scholar 

  216. Goetz, C. G., Tanner, C. M., Penn, R. D., Stebbins, G. T., Gilley, D. W., Shannon, K. M., et al. (1990) Adrenal medullary transplant to the striatum of patients with advanced Parkinson’s disease: 1-year motor and psychomotor data. Neurology 40, 273–276.

    Article  PubMed  CAS  Google Scholar 

  217. Madrazo, I., Franco-Bourland, R., Aguilera, M., Ostrosky-Solis, F., Madrazo, M., Cuevas, C., et al. (1991) Autologous adrenal medullary, fetal mesencephalic, and fetal adrenal brain transplantation in Parkinson’s disease: a longterm postoperative follow-up. J. Neural Transplant. Plast. 2, 157–164.

    Article  PubMed  CAS  Google Scholar 

  218. Goetz, C. G., Stebbins, G. T., Klawans, H. L., Koller, W. C., Grossman, R. G., Bakay, R. A., and Penn, R. D. (1991) United Parkinson Foundation Neurotransplantation Registry on adrenal medullary transplants: presurgical, and 1- and 2-year follow-up. Neurology 41, 1719–1722.

    Article  PubMed  CAS  Google Scholar 

  219. Stebbins, G. T. and Tanner, C. M. (1992) Behavioral effects of intrastriatal adrenal medullary surgery in Parkinson’s disease. In: Parkinson’s Disease: Neurobehavioral Aspects (Huber, S. J. and Cummings, J. L., eds.), Oxford University Press, New York, pp. 328–345.

    Google Scholar 

  220. Rehncrona, S. (1997) A critical review of the current status and possible developments in brain transplantation. In: Advances and Technical Standards in Neurosurgery, vol. 23 (Cohadon, F., Dolenc, V. V., Lobo Antunes, J., Nornes, H., Pickard, J. D., Reulen, H.-J., et al., eds.), Springer, Vienna, Austria, pp. 3–46.

    Chapter  Google Scholar 

  221. Hagell, P., Schrag, A., Piccini, P., Jahanshahi, M., Brown, R., Rehncrona, S., et al. (1999) Sequential bilateral transplantation in Parkinson’s disease: effects of the second graft. Brain 122, 1121–1132.

    Article  PubMed  Google Scholar 

  222. Diederich, N. J. and Goetz, C. G. (2000) Neuropsychological and behavioral aspects of transplants in Parkinson’s disease and Huntington’s disease. . Brain Cogn. 42, 294–306.

    Article  PubMed  CAS  Google Scholar 

  223. Sass, K. J., Buchanan, C. P., Westerveld, M., Marek, K. L., Farhi, A., Robbins, R. J., et al.(1995) General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson’s disease. Arch. Neurol. 52, 680–686.

    Article  PubMed  CAS  Google Scholar 

  224. Leroy, A., Michelet, D., Mahieux, F., Geny, C., Defer, G., Monfort, J.-C., et al. (1996) Examen neuropsychologique de 5 patients parkinsoniens avant et après greffe neuronale. Rev. Neurol. 152, 158–164.

    PubMed  CAS  Google Scholar 

  225. Thompson, L. L., Cullum, C. M., O’Neill, S., and Freed, C. R. (1996) Effects of fetal cell transplantation on cognitive and psychological functioning in Parkinson’s disease. Annual Meeting of the National Academy of Neuropsychology, New Orleans.

    Google Scholar 

  226. Baker, K. K., Ramig, L. O., Johnson, A. B., and Freed, C. R. (1997) Preliminary voice and speech analysis following fetal dopamine transplants in 5 individuals with Parkinson disease. J. Speech Lang. Hear. Res. 40, 615–626.

    PubMed  CAS  Google Scholar 

  227. Molina, H., Quinones, Alvarez, L., et al. (1991) Transplantation of human fetal mesencephalic tissue in caudate nucleus as treatment for Parkinson’s disease: the Cuban experience. In: Intracerebral Transplantation in Movement Disorders: Experimental Basis and Clinical Experiences (Lindvall, I., Björklund, A., and Widner, H., eds.), Elsevier, Amsterdam, pp. 99–110.

    Google Scholar 

  228. Madrazo, I., Franco-Bourland, R. E., Castrejon, H., Cuevas, C., and Ostrosky-Solis, F. (1995) Fetal striatal homotransplantation for Huntington’s disease: first two case reports. Neurol. Res. 17, 312–315.

    PubMed  CAS  Google Scholar 

  229. Price, L. H., Spencer, D. D., Marek, K. L., Robbins, R. J., Leranth, C., Farhi, A., et al. (1995) Psychiatric status after human fetal mesencephalic tissue transplantation in Parkinson’s disease. Biol. Psychiatry 38, 498–505.

    Article  PubMed  CAS  Google Scholar 

  230. Freed, C. R., Greene, P. E., Breeze, R. E., Tsai, W.-Y., DuMouchel, W., Kao, R., et al. (2001) Transplantation of embryonic dopamine neurons for severe Parkinson’s disease. N. Engl. J. Med. 344, 710–719.

    Article  PubMed  CAS  Google Scholar 

  231. Philpott, L. M., Kopyov, O. V., Lee, A. J., Jacques, S., Duma, C. M., Caine, S., et al. (1997) Neuropsychological functioning following fetal striatal transplantation in Huntington’s chorea: three case presentations. Cell Transplant. 6, 203–212.

    Article  PubMed  CAS  Google Scholar 

  232. Hagell, P., Crabb, L., Pogarell, O., Schrag, A., Widner, H., Brooks, D. J., et al. (2000) Health-related quality of life following bilateral intrastriatal transplantation in Parkinson’s disease. Mov. Disord. 15, 224–229.

    Article  PubMed  CAS  Google Scholar 

  233. Schumacher, J. M., Ellias, S. A., Palmer, E. P., Kott, H. S., Dinsmore, J., Dempsey, P. K., et al. (2000) Transplantation of embryonic porcine mesencephalic tissue in patients with PD. Neurology 54, 1042–1050.

    Article  PubMed  CAS  Google Scholar 

  234. Haberler, C., Alesch, F., Mazal, P. R., Pilz, P., Jellinger, K., Pinter, M. M., et al. (2000) No tissue damage by chronic deep brain stimulation in Parkinson’s disease. Ann. Neurol. 48, 372–376.

    Article  PubMed  CAS  Google Scholar 

  235. Crown, S. (1971) Psychosomatic aspects of Parkinsonism. J. Psychosom. Res. 15, 451–459.

    Article  PubMed  CAS  Google Scholar 

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Tröster, A.I., Fields, J.A. (2003). The Role of Neuropsychological Evaluation in the Neurosurgical Treatment of Movement Disorders. In: Tarsy, D., Vitek, J.L., Lozano, A.M. (eds) Surgical Treatment of Parkinson’s Disease and Other Movement Disorders. Current Clinical Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-312-5_15

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