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The Kidney

Diabetic Nephropathy

  • Chapter
Type 1 Diabetes

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Diabetic nephropathy is a serious and costly microvascular complication of both type 1 and type 2 diabetes. It has been a subject of study for over two centuries. Richard Bright (1789–1858) is often credited for the observation that albuminuria reflects serious diabetic renal involvement (1,2). Elliott P. Joslin (1869–1962), one of the first diabetologists stated, “the renal complications of diabetes have been unimportant in the past, but with the prolongation of life which modern treatment is bringing about they will deserve attention” (3). This statement, made 5 yr before the introduction of insulin in 1917 has, unfortunately, been proven correct because more than onethird of patients entering maintenance dialysis today suffer from diabetic nephropathy.

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  1. Abhay Vats MD
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  2. Frederick DeRubertis MD
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Editors and Affiliations

  1. Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Mark A. Sperling MD (Professor of Pediatrics and Chair Emeritus) (Professor of Pediatrics and Chair Emeritus)

  2. Division of Endocrinology, Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Mark A. Sperling MD (Professor of Pediatrics and Chair Emeritus) (Professor of Pediatrics and Chair Emeritus)

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Vats, A., DeRubertis, F. (2003). The Kidney. In: Sperling, M.A. (eds) Type 1 Diabetes. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-310-1_23

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