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Methylsulfonylmethane (Dimethylsulfone)

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Part of the book series: Forensic Science and Medicine ((FSM))

Abstract

Methylsulfonylmethane (dimethylsulfone; MSM) is a natural product whose primary use has been as a high-temperature solvent in the chemical industry. Early therapeutic uses included its application as an antiinflammatory agent (Merck Index, 1996).

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References

  • Anonymous. Pharmacy fax monitor. July 18, 2001.

    Google Scholar 

  • Barrager E, Veltmann JR Jr, Schauss AG, Schiller RN. A multicentered, open-label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis. J Altern Complement Med 2002; 3: 167–73.

    Article  Google Scholar 

  • Childs SJ. Dimethyl sulfone (DMSO2) in the treatment of interstitial cystitis. Urol Clin North Am 1994; 21: 85–8.

    PubMed  CAS  Google Scholar 

  • ConsumerLab.com. News. Consumerlab.com reports test results of arthritis supplement—MSM. Quality found higher than for most supplements, but room for improvement remains. Available from: http://www.consumerlabs.com/news/news_060410.aspAccessed January 25, 2002.

  • Goldstein P, Magnano L, Rojo J. Effects of dimethyl sulfone (DMSO2) on early gametogenesis in Caenorhabditis elegans: ultrastructural aberrations and loss of synaptonemal complexes from pachytene nuclei. Reprod Toxicol 1992; 6: 149–59.

    Article  PubMed  CAS  Google Scholar 

  • Hucker HB, Ahmad PM, Miller EA, Brobyn R. Metabolism of dimethyl sulphoxide to dimethyl sulphone in the rat and man. Nature 1966; 209: 619–20.

    Article  PubMed  CAS  Google Scholar 

  • Klandorf H, Chirra AR, DeGruccio A, Girman DJ. Dimethyl sulfoxide modulation of diabetes onset in NOD mice. Diabetes 1989; 38: 194–7.

    Article  PubMed  CAS  Google Scholar 

  • Layman DL, Jacob SW. The absorption, metabolism and excretion of dimethyl sulfoxide by rhesus monkeys. Life Sci 1985; 37: 2431–7.

    Article  PubMed  CAS  Google Scholar 

  • Mehta AC, Peaker S, Acomb C, Calvert RT. Rapid gas chromatographic determination of dim-ethyl sulphoxide and its metabolite dimethyl sulphone in plasma and urine. J Chromatogr 1986; 383: 400–4.

    Article  PubMed  CAS  Google Scholar 

  • Natural Medicines Database. Methylsulfonylmethane. In: Jellin, JM, ed. Natural medicines comprehensive database, 2002, Therapeutic Research Faculty. Available from: http://www.naturaldatabase.com/monograph.aspmono_id=522hilite=1, Accessed January 16, 2002.

  • O’Dwyer PJ, McCabe DP, Sickle-Santanello BJ, et al. Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer. Cancer 1988; 62: 944–8.

    Article  PubMed  Google Scholar 

  • Pearson TW, Dawson Hi, Lackey HB Natural occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains, and beverages. J Agric Food Chem 1981; 29: 1089–91.

    Article  PubMed  CAS  Google Scholar 

  • Richmond VL. Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins. Life Sci 1986; 39: 263–8.

    Article  PubMed  CAS  Google Scholar 

  • The Merck Index. Whitehouse Station: Merck Research Laboratories, 1996.

    Google Scholar 

  • Williams KI, Burstein SH, Layne DS. Dimethyl sulfone: isolation from cows’ milk. Proc Soc Exp Biol Med 1966a; 122: 865–6.

    Article  PubMed  CAS  Google Scholar 

  • Williams KI, Burstein SH, Layne DS. Dimethyl sulfone: isolation from human urine. Arch Biochem Biophys 1966b; 113: 251–2.

    Article  PubMed  CAS  Google Scholar 

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© 2003 Springer Science+Business Media New York

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Tracy, T.S., Cupp, M.J. (2003). Methylsulfonylmethane (Dimethylsulfone). In: Cupp, M.J., Tracy, T.S. (eds) Dietary Supplements. Forensic Science and Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-303-3_18

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  • DOI: https://doi.org/10.1007/978-1-59259-303-3_18

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9726-7

  • Online ISBN: 978-1-59259-303-3

  • eBook Packages: Springer Book Archive

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