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Opioids, Sedation, and Sleep

Different States, Similar Traits, and the Searchfor Common Mechanisms

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Sedation and Analgesia for Diagnostic and Therapeutic Procedures

Part of the book series: Contemporary C Neuroscience ((CCNE))

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Abstract

Sedation is an area of active research motivated by the clinical need for safe and reliable techniques. An understanding of the cellular and molecular physi-ology of sedation will contribute to the rational development of sedating drugs. These important goals are hampered, however, by the complexity of sedation as an altered State of arousal and by the diversity of sedating drugs. The purpose of this chapter is to selectively review data in support of a working hypothesis that conceptually unifies efforts to understand the neurochemical basis of sedation.

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  1. Ralph Lydic PhD
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  2. Helen A. Baghdoyan PhD
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  3. Jacinta McGinley MB, FFARCSI
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Editors and Affiliations

  1. Department of Anesthesiology, University of Michigan Health System, Ann Arbor, MI, USA

    Shobha Malviya MD , Norah N. Naughton MD  & Kevin K. Tremper MD, PhD ,  & 

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Lydic, R., Baghdoyan, H.A., McGinley, J. (2003). Opioids, Sedation, and Sleep. In: Malviya, S., Naughton, N.N., Tremper, K.K. (eds) Sedation and Analgesia for Diagnostic and Therapeutic Procedures. Contemporary Clinical Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-295-1_1

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