Abstract
Calcitonin (CT) is a 32-aminoacid peptide that is secreted by thyroidal C cells in mammals and by the ultimobranchial gland in submammals. CT, that was originally identified as a hypocalcemic factor present in bovine serum (1) exerts its hypocalcemic effects primarily by directly inhibiting osteoclastic bone resorption (2).
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Gennari, C. (2003). Basic Aspects of Calcitonin in Skeletal Health. In: Orwoll, E.S., Bliziotes, M. (eds) Osteoporosis. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-278-4_20
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