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Influenza Vaccines

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Combination Vaccines

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Abstract

Disease caused by influenza virus infection is not a trivial matter. In the United States influenza can kill 10,000 people in a nonpandemic year and 30,000 people after an acute epidemic (1). Additionally, in terms of physician and hospital expenses and time away from work, the dollar cost to the United States economy is immense. The Surgeon General of the United States Public Health Service estimated that at least 43 million Americans are at risk of death from influenza by virtue of their underlying medical illness and should be immunized (2). Persons over 60 years of age and children less than one year of age have increased case-fatality rates for influenza, probably resulting from decreased immune response with age and complicating cardiopulmonary disease. As the proportion of elderly and children surviving with congenital heart and lung disease increases, so will the need for control of influenza. Additionally, pregnant women, asthmatics, diabetics, and patients receiving immunosuppressive drugs for organ transplants or neoplastic diseases are at high risk for severe influenza.

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Authors
  1. Bert E. Johansson
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  1. Vaccine Development, BioChem Pharma, Inc., Northborough, MA, USA

    Ronald W. Ellis PhD (Vice-President, General Manager) (Vice-President, General Manager)

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Johansson, B.E. (1999). Influenza Vaccines. In: Ellis, R.W. (eds) Combination Vaccines. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-265-4_6

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  • DOI: https://doi.org/10.1007/978-1-59259-265-4_6

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