Abstract
Combination vaccines present a unique clinical research challenge because, while on the one hand they are treated as new vaccine entities, they also face the challenge of replacing existing, proven vaccines. Therefore, they must fulfill all of the criteria for new vaccines in terms of safety and efficacy and in addition must be shown to be as good as the components given separately.
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Paradiso, P.R., Kohberger, R. (1999). Pediatric Combination Vaccines. In: Ellis, R.W. (eds) Combination Vaccines. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-265-4_4
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DOI: https://doi.org/10.1007/978-1-59259-265-4_4
Publisher Name: Humana Press, Totowa, NJ
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