Abstract
Multiple myeloma is characterized by the neoplastic proliferation of a single clone of plasma cells engaged in the production of a monoclonal immunoglobulin. Proliferation of the plasma cells in the bone marrow produces skeletal destruction that results in bone pain and fractures. The excessive production of the monoclonal protein (M-protein) can lead to renal failure, recurrent bacterial infections, or hyperviscosity syndrome. Anemia and hypercalcemia are other important features.
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Kyle, R.A. (2001). Multiple Myeloma and Related Disorders. In: Tefferi, A. (eds) Primary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-228-9_19
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DOI: https://doi.org/10.1007/978-1-59259-228-9_19
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-61737-122-6
Online ISBN: 978-1-59259-228-9
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