Abstract
The peripheral blood contains three principal types of white blood cells (leukocytes): granulocytes, monocytes, and lymphocytes. The granules in the granulocytes may stain neutral (neutrophils), acidic (eosinophils), or basic (basophils) under special staining procedures. In addition, neutrophils in normal peripheral blood are usually terminally differentiated (polymorphonuclear neutrophils [PMNs]), and only few immediate precursors to the PMNs (band neutrophils) are appreciated. The total white blood cell count (WBC) is determined by an automated electronic counter and is reported as cells per microliter. The differential count, which determines the percentage of each white cell subtype, is estimated by either an automated counter or by a direct morphologic examination of a peripheral blood smear (Table 1).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Suggested Reading
Cheson BD, Bennett JM, Grever M, Kay N, Keating MJ, O’Brien S, Rai KR. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 1996; 87: 4990–4997.
Italian Cooperative Study Group on Chronic Myeloid Leukemia and Italian Group for Bone Marrow Transplantation. Monitoring treatment and survival in chronic myeloid leukemia. J Clin Oncol 1999; 17: 1858–1868.
Kantarjian HM, O’Brien S, Anderlini P, Talpaz M. Treatment of myelogenous leukemia: current status and investigational options. Blood 1996; 87: 3069–3081.
Keating MJ, O’Brien S, Kantarjian H, Plunkett W, Estey E, Koller C, Beran M, Freireich EJ. Long-term follow-up of patients with chronic lymphocytic leukemia treated with fludarabine as a single agent. Blood 1993; 81: 2878–2884.
Kroft SH, Finn WG, Peterson LC. The pathology of the chronic lymphoid leukaemias. Blood Rev 1995; 9: 234–250.
Michallet M, Archimbaud E, Bandini G, Rowlings PA, Deeg HJ, Gahrton G, Montserrat E, Rozman C, Gratwohl A, Gale RP, for the European Group for Blood and Marrow Transplantation and the International Bone Marrow Transplant Registry. HLA-identical sibling bone marrow transplantation in younger patients with chronic lymphocytic leukemia. Ann Intern Med 1996; 124: 311–315.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer Science+Business Media New York
About this chapter
Cite this chapter
Tefferi, A. (2001). Leukocytosis and the Chronic Leukemias. In: Tefferi, A. (eds) Primary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-228-9_13
Download citation
DOI: https://doi.org/10.1007/978-1-59259-228-9_13
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-61737-122-6
Online ISBN: 978-1-59259-228-9
eBook Packages: Springer Book Archive