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Molecular Pathology of Pituitary Tumors

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Diagnosis and Management of Pituitary Tumors

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Abstract

Molecular biological methods have been used to study pituitary disorders in recent years. Techniques, such as Southern and Northern hybridization, in situ hybridization (ISH), polymerase chain reaction (PCR), single-strand confirmation polymorphism (SSCP) analysis, and clonal analysis, have been used to examine normal and neoplastic pituitary tissues. These methods have contributed greatly to advances in the understanding of pituitary disorders. This chapter will review some basic molecular biological techniques and illustrate their applications to the study of pituitary disorders.

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Authors
  1. Ricardo V. Lloyd MD, PhD
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Editors and Affiliations

  1. Division of Neurosurgery, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada

    Kamal Thapar MD, PhD

  2. Department of Pathology and Laboratory Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada

    Kalman Kovacs MD, PhD

  3. Department of Pathology, Mayo Clinic, Rochester, MN, USA

    Bernd W. Scheithauer MD  & Ricardo V. Lloyd MD, PhD  & 

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Lloyd, R.V. (2001). Molecular Pathology of Pituitary Tumors. In: Thapar, K., Kovacs, K., Scheithauer, B.W., Lloyd, R.V. (eds) Diagnosis and Management of Pituitary Tumors. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-217-3_8

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  • DOI: https://doi.org/10.1007/978-1-59259-217-3_8

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9693-2

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