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Diagnosis and Management of Pituitary Tumors pp 41–55Cite as

Hypothalamic—Pituitary Physiology and Regulation

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Abstract

This chapter briefly reviews the functional anatomy of the hypothalamohypophysial system, including the regulation of the major hypophysial hormones. The hypothalamohypophysial system is a major controller of integrated bodily functions, working alongside with other hormonal systems, as well as with the immune and the nervous systems. This system transmits brain signals to the various peripheral endocrine systems including the adrenals, gonads, and thyroid, which ultimately control gene expression in target tissues through peripheral hormones. Other pituitary cells transmit brain control using hormones acting on target cell surface receptors, such as prolactin, the growth hormone (GH)-insulin-like growth factor-I (IGF-I) axis, or vasopressin (VP).

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Authors
  1. Miklos L. Goth MD, PhD
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  2. Gabor B. Makara MD, DSci
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  3. Ida Gerendai MD, DSci
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Editor information

Editors and Affiliations

  1. Division of Neurosurgery, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada

    Kamal Thapar MD, PhD

  2. Department of Pathology and Laboratory Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada

    Kalman Kovacs MD, PhD

  3. Department of Pathology, Mayo Clinic, Rochester, MN, USA

    Bernd W. Scheithauer MD  & Ricardo V. Lloyd MD, PhD  & 

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© 2001 Springer Science+Business Media New York

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Goth, M.L., Makara, G.B., Gerendai, I. (2001). Hypothalamic—Pituitary Physiology and Regulation. In: Thapar, K., Kovacs, K., Scheithauer, B.W., Lloyd, R.V. (eds) Diagnosis and Management of Pituitary Tumors. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-217-3_3

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  • DOI: https://doi.org/10.1007/978-1-59259-217-3_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9693-2

  • Online ISBN: 978-1-59259-217-3

  • eBook Packages: Springer Book Archive

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