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Thyroid Cancer pp 193–208Cite as

Papillary Carcinoma

Cytology and Pathology

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Abstract

Papillary carcinoma is the most common thyroid cancer, constituting 75% to 85% of the malignant thyroid lesions in regions where iodine-deficiency goiter is no longer present (1). It represents most of the thyroid cancers that occur in children and young adults, whether idiopathic or radiation-related. A small proportion is familial. Generally, papillary carcinomas grow slowly and spread mostly by lymphatic vessels. The majority are infiltrative and without a capsule. Both gross and microscopic features are quite varied, depending on cellularity, amount and type of stroma, and the content of colloid (2,3). Nondiploid papillary cancers (1,4) and those having N-ras mutations are more likely to have metastases and to cause death (5).

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Authors
  1. James Oertel
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  2. Yolanda Oertel
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Editor information

Editors and Affiliations

  1. Department of Medicine, Washington Hospital Center, Washington, DC, USA

    Leonard Wartofsky MD, MPH, MACP (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard) (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard)

  2. Uniformed Services University of Health Sciences, Washington, DC, USA

    Leonard Wartofsky MD, MPH, MACP (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard) (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard)

  3. George Washington University of Schools of Medicine, Washington, DC, USA

    Leonard Wartofsky MD, MPH, MACP (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard) (Chairman, Professor of Medicine and Physiology, Clinical Professor of Medicine, Georgetown, Howard)

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© 2000 Springer Science+Business Media New York

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Oertel, J., Oertel, Y. (2000). Papillary Carcinoma. In: Wartofsky, L. (eds) Thyroid Cancer. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-199-2_17

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  • DOI: https://doi.org/10.1007/978-1-59259-199-2_17

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-6845-9

  • Online ISBN: 978-1-59259-199-2

  • eBook Packages: Springer Book Archive

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