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Diagnosis and Treatment of Spinal Cord Injuries and Myeloneuropathies

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Book cover Voiding Dysfunction

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

This chapter will cover the diagnosis and management of spinal-cord injuries and myeloneuropathies. In order to understand the basis of management, we will focus initially on the historical background, the neurobiology, and the general patterns of voiding dysfunction in spinal-cord injury and myelodysplasia. The general evaluation of voiding dysfunction as it pertains to each particular lesion of the spinal cord will be discussed and we will review their respective management.

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References

  1. Graham SD (1981) Present urological treatment of spinal cord injury patients. J Urol 126: 1–4.

    PubMed  CAS  Google Scholar 

  2. Bors E (1957) Neurogenic Bladder. Urol Sur 7: 177–250.

    CAS  Google Scholar 

  3. Wein A, Barrett D (1988) Voiding function and dysfunction: a logical and practical approach. Chicago: Year Book Medical Publishers.

    Google Scholar 

  4. Blaivias JG (1982) The neurophysiology of micturition: a clinical study of 550 patients. J Urol 127: 958–963.

    Google Scholar 

  5. de Groat WC, Booth AM, Yoshiyama, M (1993) Neurophysiology of micturition and its modification in animal models of human disease. In: Maggi CA, ed. The Autonomic Nervous System, vol. 3. London, Harwood Academic Publishers, 1993, pp. 227–290.

    Google Scholar 

  6. de Groat WC, Nadelhaft I, Milne RJ, Booth AM, Morgan C, Thor K (1981) Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine. J Auton Nery Syst 3: 135–160.

    Article  Google Scholar 

  7. de Groat WC, Kawatani M, Hisamitsu T, Cheng CL, Ma CP, Thor K, Steers W, Roppolo JR (1990) Mechanisms underlying the recovery of urinary bladder function following spinal cord injury. JAuton Nery Syst 30 (Suppl): S71–77.

    Article  Google Scholar 

  8. Janig W, Koltzenburg M (1990) On the function of spinal primary afferent fibres supplying colon and urinary bladder. J Auton Nery Syst 30 (Suppl): S89–96.

    Article  Google Scholar 

  9. McMahon S, Morrison J (1982) Spinal neurones with long projections activated from the abdominal viscera of the cat. J Physiol (Lond) 322: 1–20.

    CAS  Google Scholar 

  10. Hughes J (1978) Pathology of the Spinal Cord. London: Saunders.

    Google Scholar 

  11. Schall T, Bacon K (1994) Chemokines, leucocyte trafficking, and inflammation. Curr Opin Immunol 6: 865–873.

    Article  PubMed  CAS  Google Scholar 

  12. Fagg GE, Foster AC (1983) Amino acid neurotransmitters and their pathways in the mammalian central nervous system. Neuroscience 9: 701–709.

    Article  PubMed  CAS  Google Scholar 

  13. Rothman S, Olney J (1987) Excitotoxicity and the NMP receptor. Trends Neurosc 10: 299–302.

    Article  CAS  Google Scholar 

  14. Wein AJ (1981) Classification of neurogenic voiding dysfunction. J Urol 125: 605609.

    Google Scholar 

  15. Bors E, Comarr AE (1971) Disturbances of micturition: acute onset. Neurolog Urol University Park, Baltimore, MD. 1971. pp. 181–184.

    Google Scholar 

  16. Roaf R (1960) A study of the mechanics of spinal injuries. J Bone Joint Surg 42B: 810–816.

    Google Scholar 

  17. DeVivo M, Rutt R, Black K (1982) Trends in spinal cord injury demographics and treatment outcomes between 1973 and 1986. Arch Phys Med Rehabil 73: 424–430.

    Google Scholar 

  18. Thomas D, O’Flynn K (1994) Urodynamics: Principles, Practice, Application. In: Mundy AR, Stephenson TP, Wein AJ, Spinal Cord Injury. London: Churchill Livingstone, pp. 345.

    Google Scholar 

  19. Sullivan M, Yalla S (1992) Spinal cord injury and other forms of myeloneuropathies. Problem Urol 6: 643.

    Google Scholar 

  20. Fam B, Yalla SV (1988) Vesicourethral dysfunction in spinal cord injury and its management. Semin Neurol 8: 150–155.

    Article  PubMed  CAS  Google Scholar 

  21. Wein A, Rovner E (1999) Adult voiding dysfunction secondary to neurologic disease or injury. In: Ball T, Jr., ed. AUA Update Series Vol. XVIII. AUA Office of Education, Houston, TX. pp. 42–48.

    Google Scholar 

  22. Kaplan SA, Chancellor MB, Blaivas JG (1991) Bladder and sphincter behavior in patients with spinal cord lesions. J Urol 146: 113–117.

    PubMed  CAS  Google Scholar 

  23. Wyndaele JJ (1992) Neurourology in spinal cord injured patients. Paraplegia 30: 50–53.

    Article  PubMed  CAS  Google Scholar 

  24. Curt A, Rodic B, Schurch B, Dietz V (1997) Recovery of bladder function in patients with acute spinal cord injury: significance of ASIA scores and somatosensory evoked potentials. Spinal Cord 35: 368–373.

    Article  PubMed  CAS  Google Scholar 

  25. Rudy D, Awad S, Downie J (1988) External sphincter dyssynergia: an abnormal continence reflux. J. Urol 140: 105–110.

    PubMed  CAS  Google Scholar 

  26. de Groat W, Karvatni M (1985) Neural control of the urinary bladder: Possible relationship between peptidergic inhibitory mechanisms and detrusor instability. Neurourol Urodyn 4: 285–300.

    Article  Google Scholar 

  27. Anderson RU (1983) Urodynamic patterns after acute spinal cord injury: association with bladder trabeculation in male patients. J Urol 129: 777–779.

    PubMed  CAS  Google Scholar 

  28. Ruutu M (1985) Cystometrographic patterns in predicting bladder function after spinal cord injury. Paraplegia 23: 243–252.

    Article  PubMed  CAS  Google Scholar 

  29. Chancellor MB, Rivas DA, Linsenmeyer T, Abdill CA, Ackman CF, Appell RA, et al. (1994) Multicenter trial in North America of UroLume urinary sphincter prosthesis. J Urol 152: 924–930.

    PubMed  CAS  Google Scholar 

  30. McGuire E (1984) Clinical evaluation and treatment of neurogenic vesical dysfunction. In: Libertino J, ed., International Perspectives in Urology. Baltimore: Williams and Wilkins.

    Google Scholar 

  31. Sundin T, Dahlstrom A (1973) The sympathetic innervation of the urinary bladder and urethra in the normal state and after parasympathetic denervation at the spinal root level. An experimental study in cats. Scand J Urol Nephrol 7: 131–149.

    Article  PubMed  CAS  Google Scholar 

  32. Lloyd L (1986) New trends in urologic management in spinal cord injured patients. J Cent Nery Syst Trauma 3: 3–12.

    CAS  Google Scholar 

  33. Guttman L, Frankel H (1966) The value of intermittent catheterisation in the early management of traumatic paraplegia and tetraplegia. Paraplegia 4: 63–84.

    Article  Google Scholar 

  34. Stein SC, Feldman JG, Friedlander M, Klein RI (1982) Is myelomeningocele a disappearing disease? Pediatrics 69: 511–514.

    PubMed  CAS  Google Scholar 

  35. Laurence K (1989) A declining incidence of neural tube defects in UK. Z Kinderchir 44 (Suppl 1): 51.

    PubMed  Google Scholar 

  36. Stark G (1977) Spina Bifida: Problems and Management. Oxford: Blackwell Scientific Publications.

    Google Scholar 

  37. Toriello H (1982) Periconceptual vitamin supplementation for the prevention of neural tube defects: a review. Spinal Bifida Therapy 4: 59.

    Google Scholar 

  38. Scarff T, Fronczak S (1981) Myleomeningocele: a review and update. Rehab Lit 42: 143–146.

    PubMed  CAS  Google Scholar 

  39. MRC Vitamin Study Research Group (1991) Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338: 131–137.

    Google Scholar 

  40. Werler MM, Shapiro S, Mitchell AA (1993) Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA 269: 1257–1261.

    Article  PubMed  CAS  Google Scholar 

  41. Hobbins J, Grannum P, Berkowitz RL, et al. (1979) Ultrasound in the diagnosis of congenital anomalies. Am J Obstet Gynecol 134: 331–345.

    PubMed  CAS  Google Scholar 

  42. Brock DJH, Sutcliffe RG (1972) Alpha Fetoprotein in the antenatal diagnosis of anencephaly and spina bifida. Lancet 2: 197–199.

    Article  PubMed  CAS  Google Scholar 

  43. Watson WJ, Chescheir NC, Katz VL, Seeds JW (1991) The role of ultrasound in evaluation of patients with elevated maternal serum alpha-fetoprotein: a review. Obstet Gynecol 78: 123–128.

    PubMed  CAS  Google Scholar 

  44. Chervenak FA, Duncan C, Ment LR, et al. (1984) Perinatal management of myelomeningocele. Obstet Gynecol 63: 376–380.

    PubMed  CAS  Google Scholar 

  45. Bensen JT, Dillard RG, Burton BK (1988) Open spina bifida: Does caesarian section improve prognosis. Obstet Gynecol 71: 532–534.

    PubMed  CAS  Google Scholar 

  46. McGuire E, Woodside J, Ta B, et al. (1981) Prognostic value of urodynamic testing in myelodysplastic patients. J Urol 126: 205–209.

    PubMed  CAS  Google Scholar 

  47. Kroovand RL, Bell W, Hart LJ, Benfield KY (1990) The effect of back closure on detrusor function in neonates with myelomeningocele. J Urol 144: 423–425.

    PubMed  CAS  Google Scholar 

  48. McGuire E, Denil J Adult myelodysplasia. In: AUA Update Series Vol. X. AUA Office of Education. Houston, TX. 1991. pp. 297.

    Google Scholar 

  49. Blaivas JG (1980) Management of bladder dysfunction in multiple sclerosis. Neurology 30: 12–18.

    Article  PubMed  CAS  Google Scholar 

  50. Lapides J, Diokno A, Silber S, Lowe B (1972) Clean intermittent self-catheterization in the treatment of urinary tract disease. J Urol 107: 7458–7461.

    Google Scholar 

  51. McGuire E, Savastano J (1986) Comparative urological outcome in women with spinal cord injury. J Urol 135: 730–731.

    PubMed  CAS  Google Scholar 

  52. Swierzewski SJ, 3rd, Gormley EA, Belville WD, Sweetser PM, Wan J, McGuire EJ (1994) The effect of terazosin on bladder function in the spinal cord injured patient. J Urol 151: 951–954.

    PubMed  Google Scholar 

  53. Sundin T, Dahlstrom A, Norlen L, Svedmyr N (1977) The sympathetic innervation and adrenoreceptor function of the human lower urinary tract in the normal state and after parasympathetic denervation. Invest Urol 14: 322–328.

    PubMed  CAS  Google Scholar 

  54. Sogbein SK, Downie JW, Awad SA (1984) Urethral response during bladder contraction induced by subcutaneous bethanechol chloride: elicitation of a sympathetic reflex urethral constriction. J Urol 131: 791–795.

    PubMed  CAS  Google Scholar 

  55. D’Agostino G, Kilbinger H, Chiari MC, Grana E (1986) Presynaptic inhibitory muscarinic receptors modulating (3H) acetylcholine release in the rat urinary bladder. J Pharm Exper Ther 239: 522–528.

    Google Scholar 

  56. Somogyi G, de Groat W (1990) Modulation of the release of (3H) norepinephrine from the base and body of the rat urinary bladder by endogenous adrenergic and cholinergic mechanisms. J Pharmacol Exp Ther 255: 204–210.

    PubMed  CAS  Google Scholar 

  57. Alberts P (1995) Classification of the presynaptic muscarinic receptor subtype that refulates 3H-acetylcholine secretion in the guinia pig urinary bladder in vitro. J Pharmacol Exp Ther 274: 458–468.

    PubMed  CAS  Google Scholar 

  58. Seze M, Wiart L, Joseph P (1998) Capsaicin and neurogenic detrusor hyperreflexia: A double-blind placebo controlled study in 20 patients with spinal cord lesions. Neurourol Urodynamics 17: 513–523.

    Article  Google Scholar 

  59. Perkash I (1976) Modified approach to sphincterotomy in spinal cord injury patients: Indications, technique, and results in 32 patients. Paraplegia 13: 247–260.

    PubMed  CAS  Google Scholar 

  60. Wein A, Raezer D, Benson G (1976) Management of neurogenic bladder dysfunction in the adult. Urology 8: 432–434.

    Article  PubMed  CAS  Google Scholar 

  61. Carrion H, Braun B, Politano V (1979) External sphincterotomy at the 12 o’clock position. J Urol 121: 462.

    PubMed  CAS  Google Scholar 

  62. Madersbacher H (1976) The twelve o’clock sphincterotomy: Technique, indications, results. Paraplegia 13: 261–267.

    PubMed  CAS  Google Scholar 

  63. Kiviat M (1975) Transurethral sphincterotomy: Relationship of site of incision to postoperative potency and delayed hemorrhage. J Urol 114: 399–401.

    PubMed  CAS  Google Scholar 

  64. Schellhammer P, Hackler R, Bunts R (1973) External sphincterotomy: An evaluation of 150 patients with neurogenic bladder. J Urol 110: 199–202.

    PubMed  CAS  Google Scholar 

  65. Yalla S, Fam B, Gabilondo F, Jacobs J, DiBenedetto M, etal. (1977) Anteromedian external sphincterotomy: technique, rationale, and complications. J Urol 117: 489493.

    Google Scholar 

  66. Thomas D (1976) The effect of trans-urethral surgery on penile erection in spinal injury patients. Paraplegia 13: 286–289.

    PubMed  CAS  Google Scholar 

  67. Vapnek JM, Couillard DR, Stone AR (1994) Is sphincterotomy the best management of the spinal cord injured bladder? J Urol 151: 961–964.

    PubMed  CAS  Google Scholar 

  68. Rivas D, Chancellor M, Bagley, D (1994) Prospective comparison of external sphincter prosthesis placement and external sphincterotomy in men with spinal cord injury. J Endourol 8: 89–93.

    Article  PubMed  CAS  Google Scholar 

  69. Moeller B (1977) Some observations on 31 spinal cord injury patients on whom the Bricker procedure was performed. Paraplegia 15: 230.

    Article  PubMed  CAS  Google Scholar 

  70. Boyce WH, Lathem JE, Hunt LD (1964) Research related to the development of an artificial electrical stimulator for the paralyzed human bladder: a review. J Urol 91: 41–51.

    PubMed  CAS  Google Scholar 

  71. Brindley GS, Polkey CE, Rushton DN, Cardoza L (1986) Sacral anterior root stimulators for bladder control in paraplegia: The first 50 cases. J Neurol Neurosurg, Psychiat, 49: 1104–1114.

    Article  CAS  Google Scholar 

  72. Tanagho EA, Schmidt RA, Orvis BR (1989) Neural stimulation for control of voiding dysfunction: a preliminary report in 22 patients with serious neuropathic voiding disorders. J Urol 142: 340–345.

    PubMed  CAS  Google Scholar 

  73. Kerrebroech P, Koldewijn E, Debruyne M (1993) Worldwide experience with the Finetech-Brindley Sacral Anterior Root Stimulator. Neurol Urodynamics 12: 497503.

    Google Scholar 

  74. Merrill DC (1979) The treatment of detrusor incontinence by electrical stimulation. J Urol 122: 515–517.

    PubMed  CAS  Google Scholar 

  75. Hackler RH (1977) A 25-year prospective mortality study in the spinal cord injured patient: comparison with the long-term living paraplegic. J Urol 117: 486–488.

    PubMed  CAS  Google Scholar 

  76. Jonas U, Jones LW, Tanagho EA (1975) Recovery of bladder function after spinal cord transection. J Urol. 113: 626–628.

    PubMed  CAS  Google Scholar 

  77. Young J. Spinal cord injury statistics: Experience of regional spinal injury systems. Good Samaritan Medical Center Phoenix, AZ. 1982 p. 152.

    Google Scholar 

  78. Bors E (1957) Neurogenic bladder. Urologic Survey 7:177.

    Google Scholar 

  79. Duckett JW, Jr (1982) Ureterovesical junction and acquired vesicoureteral reflux. J Urol 127: 249.

    PubMed  Google Scholar 

  80. Hall MK, Hackler RH, Zampieri TA, Zampieri JB (1989) Renal calculi in spinal cord-injured patient: association with reflux, bladder stones, and foley catheter drainage. Urology 34: 126–128.

    Article  PubMed  CAS  Google Scholar 

  81. Claus-Walker J, Campos R, Carter R, Vallbona C, Liscomb H (1972) Calcium excretion in quadraplegia. Arch Phys Med Rehabil 53: 14–20.

    PubMed  CAS  Google Scholar 

  82. Trop CS, Bennett CJ (1991) Autonomic dysreflexia and its urological implications: a review. J Urol 146: 1461–1469.

    PubMed  CAS  Google Scholar 

  83. Dykstra DD, Sidi AA, Anderson LC (1987) The effect of nifedipine on cystoscopyinduced autonomic hyperreflexia in patients with high spinal cord injuries. J Urol 138: 1155–1157.

    PubMed  CAS  Google Scholar 

  84. Chancellor MB, Erhard MJ, Hirsch IH, Stass WE Jr (1994) Prospective evaluation of terazosin for the treatment of autonomic dysreflexia. J Urol 151: 111–113.

    PubMed  CAS  Google Scholar 

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Authors
  1. Steven W. Sukin MD
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  2. Timothy B. Boone MD, PHD
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Editor information

Editors and Affiliations

  1. Section of Voiding Dysfunction and Female Urology, Department of Urology, Cleveland Clinic Foundation, Cleveland, OH, USA

    Rodney A. Appell MD

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© 2000 Humana Press Inc., Totowa, NJ

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Sukin, S.W., Boone, T.B. (2000). Diagnosis and Treatment of Spinal Cord Injuries and Myeloneuropathies. In: Appell, R.A. (eds) Voiding Dysfunction. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-198-5_5

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  • DOI: https://doi.org/10.1007/978-1-59259-198-5_5

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9689-5

  • Online ISBN: 978-1-59259-198-5

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