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Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation

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Xenotransplantation

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Abstract

Over the past decade, substantial increases in transplant organ and recipient survival have been accompanied by a significant increase in the quality of life for patients with end-stage organ failure. However, the increasing access to organ transplant lists, coupled with static or even falling organ donation rates, have resulted in a doubling of the waiting time for patients receiving a cadaveric kidney at many major centers in the United States (http://www.unos.org). In addition, many patients waiting for suitable heart or liver donors die because of the lack of effective life-support systems. Living donor transplantation has the potential to alleviate renal allograft shortages but comparable procedures have been performed for lung and liver in only a few specialized centers to date.

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Authors
  1. Simon C. Robson FRCP (UK), PhD
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Editors and Affiliations

  1. Transplantation Biology and the Departments of Surgery, Immunology, and Pediatrics, Mayo Clinic, Rochester, MN, USA

    Jeffrey L. Platt MD

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© 2002 Springer Science+Business Media New York

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Robson, S.C. (2002). Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation. In: Platt, J.L. (eds) Xenotransplantation. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-166-4_11

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  • DOI: https://doi.org/10.1007/978-1-59259-166-4_11

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-127-1

  • Online ISBN: 978-1-59259-166-4

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