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Essentials of Anatomic Pathology pp 463–502Cite as

Soft Tissue Tumors

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General

  • Weiss, SW, Goldblum, JR. Soft Tissue Tumors. 4th ed, 2001.

    Google Scholar 

  • Meis-Kindblom JM, Enzinger FM. Color Atlas of Soft Tissue Tumors, 1996.

    Google Scholar 

Fibrous Tumors

  • Chung EB, Enzinger FM. Infantile fibrosarcoma. Cancer 1976; 38: 729–739.

    Article  PubMed  CAS  Google Scholar 

  • Chung EB, Enzinger FM. Infantile myofibromatosis. Cancer 1981, 48: 807–1818.

    Article  Google Scholar 

  • Schmookler BM, Enzinger FM, Weiss SW. Giant cell fibroblastoma. A juvenile form of dermatofibrosarcoma protuberans. Cancer 1989; 64: 2154–2161.

    Article  Google Scholar 

  • Burke AP, Sobin LH, Shekitka KM et al. Intra-abdominal fibromatosis. A pathologic analysis of 130 tumors with comparison of clinical subgroups. Am J Surg Pathol. 1990; 14 335–341.

    Article  PubMed  CAS  Google Scholar 

  • Meis JM, Enzinger FM. Inflammatory fibrosarcoma of the mesentery and retroperitoneum. Am J Surg Pathol. 1991; 15: 1146–1116.

    Article  PubMed  CAS  Google Scholar 

  • Hollowood K, Fletcher CDM. Pseudosarcomatous myofibroblast c proliferations of the spermatic cord. Am J Surg Pathol 1992; 16: 448–454.

    Article  PubMed  CAS  Google Scholar 

  • Meis JM, Enzinger FM. Proliferative fasciitis and myositis of childhood. Am J Surg Pathol 1992; 16: 364–372.

    Article  PubMed  CAS  Google Scholar 

  • Evans HL et al. Low grade fibromyxoid sarcoma. A report of 12 cases. Am J Surg Pathol 1993; 17: 595–600.

    Article  PubMed  CAS  Google Scholar 

  • Schofield DE et al. Fibrosarcoma in infants and children. Application of new techniques. Am J Surg Pathol 1994; 18: 14–24.

    Article  PubMed  CAS  Google Scholar 

  • Coffin CM et al. Inflammatory myofibroblastic tumor: a clinico-pathologic and immunohistochemical study of 84 cases. Am J Surg Pathol 1995; 19: 859–872.

    Article  PubMed  CAS  Google Scholar 

  • Suster S et al. Solitary fibrous tumors of soft tissue. Am J Surg Pathol 1995; 19: 1257–1266.

    Article  PubMed  CAS  Google Scholar 

Fibrohistiocytic Tumors

  • Weiss SW, Enzinger FM. Malignant fibrous histiocytoma. An analysis of 200 cases. Cancer 1978; 41: 2250–2266.

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM. Angiomatoid malignant fibrous histiocytoma. A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer 1979; 44: 2147–2157.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM, Evans BJ, Macartney JC, Smith N, Wilson Jones E, McKee PH. Dermatofibrosarcoma protuberans: A clinicopathological and immunohistochemical study with a review of the literature. Histopathology 1985; 9: 921–938.

    Article  PubMed  CAS  Google Scholar 

  • Sonoda T, Hashimoto H. Enjoji M. Juvenile xanthogranuloma. Clinicopathologic analysis and immunohistochemical study of 57 patients. Cancer 1985; 56: 2280–2286.

    Article  PubMed  CAS  Google Scholar 

  • Leong AS, Milios J. Atypical Fibroxanthoma of the skin: A clinicopathologic and immunohistochemical study and a discussion of its histogenesis. Histopathology 1987; 11: 463–475.

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM, Zhang R. Plexiform fibrohistiocytic tumor presenting in children and young adults. An analysis of 65 cases. Am J Surg Pathol 1988; 12: 818–826.

    Article  PubMed  CAS  Google Scholar 

  • Costa MJ, Weiss SW. Angiomatoid malignant fibrous histiocytoma. A follow-up study of 108 cases. Am J Surg Pathol 1990; 14: 1126–1132.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM. Benign fibrous histiocytoma of subcutaneous and deep soft tissue: A clinicopathological analysis of 21 cases. Am J Surg Pathol 1990; 14: 801–809.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM. Pleomorphic malignant fibrous histiocytoma: Fact or fiction? A critical reappraisal based upon 158 tumors diagnosed as pleomorphic sarcoma. Am J Surg Pathol 1992; 14: 213–228.

    Article  Google Scholar 

  • Calonje E et al. Cellular benign fibrous histiocytoma: Analysis of 74 cases. Am J Surg Pathol 1994; 18: 668–676.

    Article  PubMed  CAS  Google Scholar 

  • Mentzel T. et al. Myxofibrosarcoma: Clinicopathologic analysis of 75 cases with emphasis on the low grade variant. Am J Surg Pathol 1996; 20: 391–405.

    Article  PubMed  CAS  Google Scholar 

Lipomatous Tumors

  • Schmookler BM, Enzinger FM. Pleomorphic lipoma: A benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer 1981; 47: 126–133.

    Article  Google Scholar 

  • Silverman TA, Enzinger FM. Fibrolipomatous hamartoma of nerve. A clinicopathologic analysis of 26 cases. Am J Surg Pathol 1985; 9: 7–14.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM, Martin-Bates E. Spindle cell lipoma: A clinico-pathological study with some original observations. Histopathology 1987; 11 803–817.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM, Martin-Bates E. Intramuscular and intermuscular lipoma: neglected diagnoses. Histopathology 1988; 12: 275–287.

    Article  PubMed  CAS  Google Scholar 

  • Meis JM, Enzinger FM. Myolipoma of soft tissue. Am J Surg Pathol 1991; 15: 121–125.

    Article  PubMed  CAS  Google Scholar 

  • Aman P et al. Rearrangement of the transcription factor gene CHOP in myxoid liposarcoma with t(12;16) (g13;p11). Genes Chromos Cancer 1992; 5: 278–285.

    Article  PubMed  CAS  Google Scholar 

  • Chan JKC et al. Lymphangiomyomatosis and angiomyolipoma: Closely related lesions characterized by hamartomatous proliferations of HMB-45-positive smooth muscle. Histopathology 1992; 22: 445–445.

    Article  Google Scholar 

  • Weiss SW, Rao VK. Well differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum and miscellaneous sites. Am J Surg Pathol 1992; 16: 1051–1058.

    Article  PubMed  CAS  Google Scholar 

  • Dal Cin P et al. Cytogenetic and FISH investigation of ring chromosomes characterizing a specific pathologic subgroup of adipose tissue tumors. Cancer Genet Cytogenet 1993; 68: 85–90.

    Article  Google Scholar 

  • Meis JM, Enzinger FM. Chondroid lipoma. A unique tumor simulating liposarcoma and myxoid liposarcoma. Am J Surg Pathol 1993; 17: 1103–1112.

    Article  PubMed  CAS  Google Scholar 

  • Henricks WH et al. Dedifferentiated liposarcoma. A clinicopathologic analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am J Surg Pathol 1997; 21: 271–281.

    Article  PubMed  CAS  Google Scholar 

Smooth Muscle Tumors

Skeletal Muscle Tumors

  • Enzinger FM, Shiraki M. Alveolar rhabdomyosarcoma. An analysis of 110 cases. Cancer 1969; 24: 18–31.

    Article  PubMed  CAS  Google Scholar 

  • Di Sant’Agnese PA, Knowles DM. Extracardiac rhabdomyoma: a clinicopathologic study and review of the literature. Cancer 1980; 46: 780–789.

    Article  PubMed  Google Scholar 

  • Gaffney E et al. Pleomorphic rhabdomyosarcoma in adulthood. Am J Surg Pathol 1993; 17: 601–609.

    Article  PubMed  CAS  Google Scholar 

  • Kapadia SB et al. Fetal rhabdomyoma of the head and neck. A clinicopathologic and immunophenotypic study of 24 cases. Hum Pathol 1993; 24: 754–765.

    Article  PubMed  CAS  Google Scholar 

  • Asmar L et al. Agreement among and within groups of pathologists in the classification of rhabdomyosarcoma and related childhood sarcomas. Cancer 1994; 74: 2579–2588.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM, Eusebi V. Tumors showing skeletal muscle differentiation. Semin Diagn Pathol 1994; 11: 1–81 (whole February 1994 issue).

    Google Scholar 

  • Tsokos M. The diagnosis and classification of childhood rhabdomyosarcoma. Semin Diagn Pathol 1994; 11: 26–38.

    PubMed  CAS  Google Scholar 

Vascular Tumors

  • Enzinger FM et al. Hemangiopericytoma. An analysis of 106 cases. Human Pathol 1976; 7: 61–82.

    Article  CAS  Google Scholar 

  • Olsen JG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol 1985; 12: 781–796.

    Article  PubMed  CAS  Google Scholar 

  • Weiss SW et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol 1986; 3: 259–287.

    PubMed  CAS  Google Scholar 

  • Weiss SW, Enzinger FM. Spindle cell hemangioendothelioma. A low grade angiosarcoma resembling a cavernous hemangioma and Kaposi’s sarcoma. Am J Surg Pathol 1986; 10: 521–530.

    Article  PubMed  CAS  Google Scholar 

  • Beham A. Fletcher CDM. Intramuscular angioma: Clinicopathological analysis of 74 cases. Histopathology 1991; 18: 53–59.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM et al. Spindle cell hemangioendothelioma: A clinicopathological and immunohistochemical study indicative of a non-neoplastic lesion. Histopathology 1991; 18: 291–301.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM et al. Epithelioid angiosarcoma of deep soft tissue:A distinctive tumor readily mistaken for an epithelial neoplasm. Am J Surg Pathol 1991; 15: 915–924.

    Article  PubMed  CAS  Google Scholar 

  • Tsang WYW et al. Recently characterized vascular tumors of skin and soft tissues. Histopathology 1991; 19: 489–501.

    Article  PubMed  CAS  Google Scholar 

  • Chan JKC et al. Primary vascular tumors of lymph nodes other than Kaposi’s sarcoma. Am J Surg Pathol 1992;16:335–350

    Google Scholar 

  • Calonje E et al. Retiform hemangioendothelioma: A distinctive form of low grade angiosarcoma. Am J Surg Pathol 1994; 18: 15–125.

    Google Scholar 

  • Fletcher CDM. Hemangiopericytoma–a dying breed? Curr Diagn Pathol 1994; 1: 19–23.

    Article  Google Scholar 

  • Mentzel T et al. Infantile hemangiopericytoma versus infantile myofibromatosis: Study of a series suggesting a spectrum of infantile myofibroblastic lesions. Am J Surg Pathol 1994; 18: 922–930.

    Article  PubMed  CAS  Google Scholar 

  • Nappi O et al. Hemangiopericytoma: Histopathological pattern or clinicopathologic entity? Semin Diagn Pathol 1995; 12: 221–232.

    PubMed  CAS  Google Scholar 

Synovial Tumors

  • Fisher C. Synovial sarcoma: Ultrastructural and immunohistochemical features of epithelial differentiation in monophasic and biphasic tumors. Human Pathol 1986; 17: 996.

    Article  CAS  Google Scholar 

  • Dal Cin P et al. Chromosomes in the diagnosis of soft tissue tumors. Synovial sarcoma. Modern Pathol 1992; 5: 357–362.

    Google Scholar 

  • Satti MB. Tendon sheath tumors. A pathological study of the relationship between giant cell tumor and fibroma of tendon sheath. Histopathology 1992; 20: 213–220.

    Article  PubMed  CAS  Google Scholar 

Peripheral Neural Tumors

  • Gallager RL, Helwig EB. Neurothekeoma–a benign cutaneous tumor of neural origin. Am J Surg Pathol 1980; 74: 759–764.

    CAS  Google Scholar 

  • Hashimoto H et al. Malignant neuroepithelioma (peripheral neuro- blastoma). A clinicopathologic study of 15 cases. Am J Surg Pathol 1983; 7: 309–318.

    Article  PubMed  CAS  Google Scholar 

  • Ducatman BS. Scheithauer BW, Piepgras DG, Reiman HM, 1lstrup DM. Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases. Cancer 1986; 57: 2006–2021.

    Article  PubMed  CAS  Google Scholar 

  • Barnhill RL, Mihm MC. Cellular neurothekeoma. A distinctive variant of neurothekeoma mimicking nevomelanocytic tumors. Am J Surg Pathol 1990; 14: 113–120.

    Article  PubMed  CAS  Google Scholar 

  • Suster S, Rosai J. Hamartoma of the scalp with ectopic meningothelial elements. Am J Surg Pathol 1990; 14: 1–11.

    Article  PubMed  CAS  Google Scholar 

  • White W et al. Cellular schwannoma. A clinicopathologic study of 57 patients and 58 tumors. Cancer 1990; 66: 1266–1275.

    Article  PubMed  CAS  Google Scholar 

  • Tsang WYW et al. Perineurioma: an uncommon soft tissue neoplasm. Am J Surg Pathol 1992; 16: 756–763.

    Article  PubMed  CAS  Google Scholar 

  • Mentzel T et al. Perineurioma (storiform perineurial fibroma) clinicopathological analysis of four cases. Histopathology 1994; 25: 261–267.

    Article  PubMed  CAS  Google Scholar 

Cartilaginous Tumors

  • Enzinger FM et al. Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases. Human Pathol 1972; 3: 421–435.

    Article  CAS  Google Scholar 

  • Chung EB, Enzinger FM. Chondroma of soft parts. Cancer 1978; 41: 1414–1424.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM et al. Extraskeletal myxoid chondrosarcoma: a histochemical and immunohistochemical study. Histopatholog 1986; 10: 489–499.

    Article  CAS  Google Scholar 

  • Fletcher CDM, Krausz T. Cartilaginous tumor of soft tissue. Applied Pathol 1988; 6: 208–220.

    CAS  Google Scholar 

  • Sciot R et al. (1922) (q22–31; qll-12) is a consistent marker of extra-skeletal myxoid chondrosarcoma. Mod Pathol 1995;8:765–768.

    Google Scholar 

Osseous Tumors

  • Chung EB, Enzinger FM. Extraskeletal osteosarcoma. Cancer 1987; 60: 1132–1142.

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM, Weiss S, Liang CY. Ossifying fibromyxoid tumor of soft parts. A clinicopathological analysis of 59 cases. Am J Surg Pathol 1989; 13: 817–827.

    Article  PubMed  CAS  Google Scholar 

  • Nuovo MA et al. Myositis ossificans with atypical clinical, radiographic or pathologic findings: A review of 23 cases. Skeletal Radiol 1992; 21: 87–101.

    Article  PubMed  CAS  Google Scholar 

Miscellaneous Tumors

  • Chung EB, Enzinger FM. Malignant melanoma of soft parts. A reassessment of clear cell sarcoma. Am J Surg Pathol 1983; 7: 405–413.

    Article  PubMed  CAS  Google Scholar 

  • Begin LR et al. Aggressive angiomyxoma of pelvic soft parts: a clinicopathologic study of nine cases. Human Pathol 1985; 16: 621–628.

    Article  CAS  Google Scholar 

  • Chase DR, Enzinger FM. Epithelioid sarcoma. Diagnosis, prognos- tic indicators and treatment. Am J Surg Pathol 1985; 9: 241–261.

    Article  PubMed  CAS  Google Scholar 

  • Miettinen M, Hockerstedt K, Reitamo J, Totterman S. Intramuscular myxoma–a clinicopathological study of 23 cases. Am.I Clin Pathol 1985; 84: 265–272.

    CAS  Google Scholar 

  • Khansur T, Balducci L, Tavassoli M. Granular cell tumor. Clinical spectrum of the benign and malignant entity. Cancer 1987; 60: 220–222.

    Article  PubMed  CAS  Google Scholar 

Essentials of Anatomic Pathology

  • Enzinger FM et al. Ossifying fibromyxoid tumor of soft parts. A clinicopathologic analysis of 59 cases. Am J Surg Pathol 1989; 13: 817–827.

    Article  PubMed  CAS  Google Scholar 

  • Leiberman PH et al. Alveolar soft part sarcoma. A clinicopathologic study of half a century. Cancer 1989; 63: 1–13.

    Article  Google Scholar 

  • Suster S. Rosai J. Intranodal hemorrhagic spindle cell tumor with amianthoid fibers. Report of six cases of distinctive mesenchymal neoplasm of the inguinal region that simulates Kaposi’s sarcoma. Am J Surg Pathol 1989; 13: 347–357.

    Article  PubMed  CAS  Google Scholar 

  • Weiss SW, Gnepp DR, Bratthauer GL. Palisaded myofibroblastoma. A benign mesenchymal tumor of lymph node. Am J Surg Pathol 1989; 13: 341–346.

    Article  PubMed  CAS  Google Scholar 

  • Gerald WL et al. Intra-abdominal desmoplastic small round cell tumor. Report of 19 cases. Am J Surg Pathol 1991; 15: 499–513.

    Article  PubMed  CAS  Google Scholar 

  • Lack EE et al. Undifferentiated (embryonal) sarcoma of the liver. Clinical and pathologic study of 16 cases. Am J Surg Pathol 1991; 15: 1–16.

    Article  PubMed  CAS  Google Scholar 

  • Fletcher CDM et al. Angiomyofibroblastoma of the vulva: A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol 1992; 15: 373–382.

    Article  Google Scholar 

  • Ladanyi M, Gerald M. Fusion of the EWS and WTI genes in the desmoplastic small round cell tumor. Cancer Res 1994; 54: 2937–2940.

    Google Scholar 

  • Wick MR et al. Malignant rhabdoid tumors: A clinicopathologic review and conceptual discussion. Semin Diagn Pathol 1995; 12: 233–248.

    PubMed  CAS  Google Scholar 

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Authors
  1. David Schembri-Wismayer MD
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  2. Antonio G. Nascimento MD
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Editor information

Editors and Affiliations

  1. Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA

    Liang Cheng MD

  2. University of Virginia School of Medicine, Charlottesville, VA, USA

    David G. Bostwick MD, MBA, FCAP

  3. Bostwick Laboratories, Richmond, VA, USA

    David G. Bostwick MD, MBA, FCAP

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Schembri-Wismayer, D., Nascimento, A.G. (2002). Soft Tissue Tumors. In: Cheng, L., Bostwick, D.G. (eds) Essentials of Anatomic Pathology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-162-6_13

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  • DOI: https://doi.org/10.1007/978-1-59259-162-6_13

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-58829-118-9

  • Online ISBN: 978-1-59259-162-6

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