Breast Cancer pp 325-342 | Cite as

Immunotherapy and Gene Therapy for Breast Cancer

  • Daniela Santoli
  • Sophie Visonneau
Part of the Current Clinical Oncology book series (CCO)


To this day, surgery, chemotherapy, hormonal therapy, and radiation therapy remain the main forms of treatment for breast cancer. Although these approaches reduce the risk of death and can induce complete remissions in most patients, many tumors will recur as metastatic lesions. In recent years, novel therapies have been developed that work independently or in conjunction with conventional treatments to minimize side effects and enhance therapeutic efficacy. At least two areas have emerged in which the biology of breast cancer is most likely to have a therapeutic impact. The first area involves growth factors and their receptors, the second revolves around neoangiogenesis. In addition, cell- and gene-based approaches are being evaluated in the clinic that have either a direct tumoricidal function or act by stimulating the immune system against the patient’s own tumor cells. This chapter reviews the current status of these new therapies and some of the new products that are being evaluated for clinical toxicity and preliminary efficacy.


Breast Cancer Gene Therapy Metastatic Breast Cancer Allogeneic Bone Marrow Transplantation Keyhole Limpet Hemocyanin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Daniela Santoli
  • Sophie Visonneau

There are no affiliations available

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