Abstract
Sarcomas arise from mesodermal structures. Common morphologic appearance and similar clinical patterns characterize these connective tissue tumors. The etiology is unknown, and most soft tissue sarcomas arise de novo. Soft tissue sarcomas expand radially and spread along paths of least resistance. Most develop pseudocapsules that contain tumor cells and therefore cannot be shelled out, as the risk of local recurrence is very high. Sarcomas rarely metastasize to regional lymph nodes. Hematogenous spread is common and occurs early. Pulmonary metastasis is often the first site of disseminated disease. Local recurrence is associated with disseminated disease in one-third of patients. The most important prognostic factors are histologic grade and size of tumor.
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Chang, H., Kakkis, J. (2002). Sarcoma and Lymphoma of the Breast. In: Torosian, M.H. (eds) Breast Cancer. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-161-9_19
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DOI: https://doi.org/10.1007/978-1-59259-161-9_19
Publisher Name: Humana Press, Totowa, NJ
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