Local-Regional Recurrence in Breast Cancer
The problem of local-regional recurrence of breast cancer confronts a substantial number of patients who are initially treated with apparent success. The percentage of patients who experience such recurrence varies depending on the initial stage of the disease and the form of initial breast treatment. Patients with stage I breast cancer treated with a clean margin lumpectomy and postoperative radiation therapy will have recurrence rates in the conserved breast of about 5%. In contrast, patients with Stage IIIB, initially inoperable, disease will have recurrence rates of greater than 25% on the chest wall even in the setting of successful neoadjuvant chemotherapy, mastectomy, and postoperative radiation. In patients who suffer a local-regional recurrence, one-third will have synchronous distant failure. Others subsequently develop distant disease following local-regional recurrence.
KeywordsLocal Recurrence Axillary Dissection Breast Conservation Ipsilateral Breast Tumor Recurrence Axillary Recurrence
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