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Breast Cancer pp 227-234 | Cite as

Axillary Adenopathy as the Initial Presentation of Breast Cancer

  • Shirley Scott
  • Monica Morrow
Chapter
Part of the Current Clinical Oncology book series (CCO)

Abstract

Breast cancer presenting as axillary adenopathy without clinical or radiologic breast findings is a rare clinical entity first described by Halsted in 1907 (1). These occult primary cancers are staged as TONI, stage II breast cancer when thorough clinical and radiologic investigations do not reveal the presence of a primary breast tumor. The reported incidence of this phenomenon ranges from 0.3 to 0.8% (2–5). The mean age at presentation is approximately 50 years in most series, which is similar to that of the general breast cancer population (3,5–10). This rare, but well-recognized phenomenon can present both a diagnostic and therapeutic dilemma because other occult malignancies may present as axillary adenopathy, including melanoma and carcinomas of the thyroid, lung, gastrointestinal tract, ovary, and genitourinary tract. However, the most common source of adenocarcinoma in axillary lymph nodes in women is the breast (6,11–14).

Keywords

Breast Cancer Axillary Lymph Node Breast Magnetic Resonance Imaging Axillary Lymph Node Metastasis Axillary Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Shirley Scott
  • Monica Morrow

There are no affiliations available

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