Advertisement

Breast Cancer pp 175-182 | Cite as

The Role of Surgery for Metastatic Breast Cancer

  • Lori Jardines
Chapter
Part of the Current Clinical Oncology book series (CCO)

Abstract

Breast cancer affects approximately 180,000 women annually in the United States. Despite advances in therapy, 20–30% of women who have been treated for localized breast cancer will develop metastatic disease, for which there is little chance for cure. However, a small, select group of patients with breast cancer who have isolated, distant disease are candidates for surgical resection and potential cure. In addition, surgery for palliation may also be indicated when a patient has metastatic breast cancer and symptoms that cannot be managed by other modalities. The role of surgery for breast cancer metastases to the lung, liver, and brain is discussed here in detail.

Keywords

Breast Cancer Liver Metastasis Brain Metastasis Metastatic Breast Cancer Liver Resection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Friedel G, Linder A, Toomes H (1994) The significance of prognostic factors for the resection of pulmonary metastases of breast cancer. Thorac. Cardiovasc. Surg. 42, 71–75.PubMedCrossRefGoogle Scholar
  2. 2.
    Greelish JP, Freidberg JS (2000) Secondary pulmonary malignancy. Surgi. Clin. North Am. 80, 633–657.CrossRefGoogle Scholar
  3. 3.
    Mentzer SJ, Sugarbaker DJ (2000) Management of discrete pulmonary nodules. In: Harris J (ed.), Disease of the Breast. Lippincott Williams and Wilkins, Philadelphia, PA, pp. 901–905.Google Scholar
  4. 4.
    Cahan WG, Castro EB, Huvos AG (1974) Primary breast cancer and lung carcinoma in the same patient. J. Thorac. Cardiovasc. Surg. 68, 546–550.PubMedGoogle Scholar
  5. 5.
    DeCamp M Jr, Jaklitsch M, Mentzer SJ, et al. (1995) The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases. J. Am. Coll. Surg. 181, 113–120.PubMedGoogle Scholar
  6. 6.
    Lanza L, Natarajan G, Roth JA, Putnam JB (1992) Long-term survival after resection of pulmonary metastases from carcinoma of the breast. Ann. Thorac. Surg. 54, 244–248.PubMedCrossRefGoogle Scholar
  7. 7.
    Staren E, Salerno C, Rongione A, et al. (1992) Pulmonary resection for metastatic breast cancer. Arch. Surg. 127, 1282–1284.PubMedCrossRefGoogle Scholar
  8. 8.
    Freidel G, Toomes H (1994) The significance of prognostic factors for the resection of pulmonary metastases from breast cancer. Thorac. Cardiovasc. Surg. 42, 71–75.CrossRefGoogle Scholar
  9. 9.
    Schneebaum S, Walker MJ, Young D, et al. (1994) The regional treatment of liver metastases from breast cancer. J. Surg. Oncol. 55, 26–32.PubMedCrossRefGoogle Scholar
  10. 10.
    Talamonti MS (2000) Management of discrete liver metastasis. In: Harris J (ed.), Diseases of the Breast. Lippincott Williams and Wilkins, Philadelphia, PA, pp. 907–910.Google Scholar
  11. 11.
    Jardines L, Callans LS, Torosian M (1993) Recurrent breast cancer: presentation, diagnosis, and treatment. Semin. Oncol. 20, 538–547.PubMedGoogle Scholar
  12. 12.
    Raab R, Nussbaum K-T, Behend M, et al. (1998) Liver metastases of breast cancer: results of liver resection. Anticancer Res. 18, 2231–2234.PubMedGoogle Scholar
  13. 13.
    Elias D, Lasser P, Spielman M, et al. (1991) Surgical and chemotherapeutic treatment of hepatic metastases from carcinoma of the breast. Surg. Gynecol. Obstet. 172, 461–464.PubMedGoogle Scholar
  14. 14.
    Elias D, Lasser PH, Montrucolli D, et al. (1995) Hepatectomy for liver metastases from breast cancer. Eur. J. Surg. Oncol. 21, 510–513.PubMedCrossRefGoogle Scholar
  15. 15.
    Bilchik AJ, Sarantou T, Wardlaw JC, Ramming KP (1997) Cryosurgery causes a profound reduction in tumor markers in hepatoma and non-colorectal hepatic metastases. Am. Surg. 63, 796–800.PubMedGoogle Scholar
  16. 16.
    Wen PY, Shafman TD (2000) Brain metastases. In: Harris J (ed.), Diseases of the Breast. Lippincott Williams and Wilkins, Philadelphia, PA, pp. 841–853.Google Scholar
  17. 17.
    DiStefano A, Yap HY, Hortobgyi GN, et al. (1979) The natural history of breast cancer patients: with brain metastasis. Cancer 44, 1913–1918.PubMedCrossRefGoogle Scholar
  18. 18.
    Lee Y-TN (1985) Patterns of metastasis and natural course of breast carcinoma. Cancer Metastasis Rev. 4, 153–172.PubMedCrossRefGoogle Scholar
  19. 19.
    Posner JB, Chernik NL (1978) Intracranial metastases from systemic cancer. Adv. Neurol. 19, 579–592.PubMedGoogle Scholar
  20. 20.
    Tsukada Y, Fouad A, Pickren JW, et al. (1983) Central nervous system metastasis from breast carcinoma: autopsy study. Cancer 52, 2349–2354.PubMedCrossRefGoogle Scholar
  21. 21.
    Jain S, Fisher C, Smith P, et al. (1993) Patterns of metastatic breast cancer in relation to histological type. Eur. J. Cancer 29, 2155–2157.CrossRefGoogle Scholar
  22. 22.
    Sparrow GEA, Rubens RD (1981) Brain metastases from breast cancer: clinical course, prognosis, and influence on treatment. Clin. Oncol. 7, 291–297.PubMedGoogle Scholar
  23. 23.
    Pieper DR, Hess KR, Sawaya RA (1997) Role of surgery in the treatment of brain metastases in patients with breast cancer. Ann. Surg. Oncol. 4, 481–490.PubMedCrossRefGoogle Scholar
  24. 24.
    Stewart JF, King RJ, Sexton SA, et al. (1981) Oestrogen receptors, sites of metastatic disease and survival in recurrent breast cancer. Eur. J. Cancer Clin. Oncol. 17, 449–454.Google Scholar
  25. 25.
    Wronski M, Ehud A, McCormick B (1997) Surgical treatment of 70 patients with brain metastases from breast carcinoma. Cancer 80, 1746–1754.PubMedCrossRefGoogle Scholar
  26. 26.
    Wen PY, Loeffler JS (1999) Management of brain metastases. Oncology 13, 941–966.PubMedGoogle Scholar
  27. 27.
    Patchell RA, Tibbs PA, Walsh JW, et al. (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N. Engl. J. Med. 322, 494–500.PubMedCrossRefGoogle Scholar
  28. 28.
    Boogerd W, Vos VW, Hart AA, Baris G (1993) Brain metastases in breast cancer: natural history, prognostic factors and outcome. J. Neurooncol. 13, 165–174.CrossRefGoogle Scholar
  29. 29.
    Lang EF, Slater J (1964) Metastatic brain tumor: results of surgical and non surgical treatment. Surg. Clin. North Am. 44, 865–872.PubMedGoogle Scholar
  30. 30.
    Cairncross JG, Kim J-H, Poner JB (1980) Radiation therapy for brain metastases. Ann. Neurol. 7, 529–541.PubMedCrossRefGoogle Scholar
  31. 31.
    Zinn S, Wampler GL, Stablein D, et al. (1981) Intracerebral metastases in solid tumor patients: natural history and results of treatment. Cancer 48, 384–394.CrossRefGoogle Scholar
  32. 32.
    Kamby C, Soerenson PS (1988) Characteristics of patients with short and long survivals after detection of intracranial metastases from breast cancer. J. Neurooncol. 6, 37–45.PubMedCrossRefGoogle Scholar
  33. 33.
    West J, Maor M (1980) Intracranial metastases: behavioral patterns related to primary site and results of treatment by whole brain irradiation. Int. J. Radiat. Oncol. Biol. Phys. 6, 111–115.CrossRefGoogle Scholar
  34. 34.
    Rosner D, Nemoto T, Lane WW (1986) Chemotherapy induces regression of brain metastases in breast cancer patients: update study. Cancer 58, 832–840.PubMedCrossRefGoogle Scholar
  35. 35.
    Sause WT, Crowley JJ, Morantz R, et al. (1990) Solitary brain metastasis: results of an RTOG/SWOG protocol evaluation of surgery + RT versus RT alone. Am. J. Clin. Oncol. 13, 427–432.PubMedCrossRefGoogle Scholar
  36. 36.
    Salvati M, Capoccia G, Orlando ER, et al. (1992) Single brain metastases from breast cancer: remarks on clinical pattern and treatment. Tumori 78, 115–117.PubMedGoogle Scholar
  37. 37.
    Hazuka MB, Burlson W, Stroud DN, et al. (1993) Multiple brain metastases are associated with poor survival in patients treated with surgery and radiotherapy. J. Clin. Oncol. 11, 369–375.PubMedGoogle Scholar
  38. 38.
    Bindal RK, Sawaya R, Leavens ME, et al. (1993) Surgical treatment of multiple brain metastases. J. Neurosurg. 79, 210–215.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Lori Jardines

There are no affiliations available

Personalised recommendations