Abstract
The neonicotinoid insecticides are a new generation of chemical agents that have recently been developed for commercial use. Their history can be traced to the late 1970s, when chemists at Shell Chemical Company investigated the heterocyclic nitromethylenes as potential insecticides (1,2). This research led to the discovery of nithiazine (WL 35651) (Fig. 1), which is the only representative of the early type of heterocyclic nitromethylene that has been registered for use as an insecticide. Poor photostability generally limits commercial applications for nithiazine and related (i.e., nitromethylene) compounds.
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Sheets, L.P. (2002). The Neonicotinoid Insecticides. In: Massaro, E.J. (eds) Handbook of Neurotoxicology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-132-9_6
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DOI: https://doi.org/10.1007/978-1-59259-132-9_6
Publisher Name: Humana Press, Totowa, NJ
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