Abstract
Most requests for serum and urine electrophoresis occur because of the reversal of albumin/globulin ratios in the general chemistry profile or the presence of protein in the urine. The suspicion of possible myelomatosis by the physician also alerts him/her to rule out the presence of a monoclonal gammopathy in the serum or light chain in the urine. Because of the increased sensitivity afforded by the newer electrophoresis systems, paraproteins are found more often. Their appearance in a number of conditions exhibiting a B-cell lymphoproliferative response has renewed the interest of oncologists, hematologists, nephrologists, rheumatologists, internists, and neurologists.
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Jolliff, C.R. (2001). Serum and Urine Paraprotein Capillary Electrophoresis. In: Petersen, J.R., Mohammad, A.A. (eds) Clinical and Forensic Applications of Capillary Electrophoresis. Pathology and Laboratory Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-120-6_5
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DOI: https://doi.org/10.1007/978-1-59259-120-6_5
Publisher Name: Humana Press, Totowa, NJ
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Online ISBN: 978-1-59259-120-6
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