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Clinical and Forensic Applications of Capillary Electrophoresis pp 223–233Cite as

Capillary Electrophoresis Based Immunoassay

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Part of the book series: Pathology and Laboratory Medicine ((PLM))

Abstract

Immunoassay is a procedure that involves an antigen—antibody reaction to estimate the concentration of an analyte in a sample. Over the years there has been a tremendous advancement in sensitivity and reliability of immunological assays. This was accomplished by the development of specific ultrasensitive antibodies along with automation to improve quality of results, precision, and efficiency. Initially, analytes were measured by agglutination, complement fixation, or neutralization. Focusing on the kinetics and stoichiometry of antigen—antibody reactions has allowed improvements on these basic methods. Because of these improvements, immunoassay has become a method of choice for a wide variety of clinical, pharmaceutical, environmental, and toxicological analysis.

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Authors
  1. Bode Adesoji
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  2. Amin A. Mohammad
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  3. John R. Petersen
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Editor information

Editors and Affiliations

  1. University of Texas Medical Branch, Galveston, TX, USA

    John R. Petersen  & Amin A. Mohammad  & 

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© 2001 Springer Science+Business Media New York

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Adesoji, B., Mohammad, A.A., Petersen, J.R. (2001). Capillary Electrophoresis Based Immunoassay. In: Petersen, J.R., Mohammad, A.A. (eds) Clinical and Forensic Applications of Capillary Electrophoresis. Pathology and Laboratory Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-120-6_12

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  • DOI: https://doi.org/10.1007/978-1-59259-120-6_12

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-113-4

  • Online ISBN: 978-1-59259-120-6

  • eBook Packages: Springer Book Archive

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