Abstract
The injection of bulking agents within urology has primarily confined itself to the urethra and the uretero-vesical junction. Since their inception, the injection of these materials has demonstrated both therapeutic benefit with the advantages of being minimally invasive with reductions in hospital stay, morbitity, and cost (1). From relatively simple beginnings (2, 3), there has been a significant increase in available materials, with many more undergoing clinical trial and investigation (4). Their relative abundance along with the amount of research being performed testifies to the fact that none of these agents are ideal (5). While the search continues, today’s urologist has multiple choices regarding the material that best fits their patient’s needs. Choosing which bulking agent to use can depend upon the clinical setting, the surgeon’s training, and the availability of materials and instruments. This chapter will detail the multiple aspects involved with injection therapy including the pathophysiology of urethral and uretero-vesical junction dysfunction, patient evaluation, injection techniques, and postoperative care. Following is a detailed comparison of injectable materials, including a review of published results along with the ongoing research of newer agents.
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Ordorica, R.C., Lockhart, J. (2002). Injectable Materials for Use in Urology. In: Carson, C.C. (eds) Urologic Prostheses. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-096-4_4
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