Skip to main content

Evaluation and Management of Syncope

  • Chapter
Management of Cardiac Arrhythmias

Part of the book series: Contemporary Cardiology ((CONCARD))

  • 119 Accesses

Abstract

Syncope, defined as the transient loss of consciousness and postural tone with spontaneous recovery, has fascinated, challenged, and often frustrated physicians for millennia. Indeed, the first clinical description of syncope comes from Hippocrates (the “father of medicine”), and it is from the Greek that the medical term for fainting is taken (syncopen—“to cut short”). Both a sign and a symptom, syncope can result from a bewildering array of quite varied disorders ranging from the benign and self-limited, to an indication of a serious chronic disease or a potentially fatal disorder. Perhaps no other condition so challenges the diagnostic acumen of the practitioner. This chapter reviews the epidemiology of syncope, outlines a practical approach to the evaluation of syncope, and briefly outlines the major causes of syncope, focusing on autonomic disturbances.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Savage DD, Carwin L, McGee DL, Kennel WB, Wolf PA. Epidemiologic features of isolated syncope. The Framingham Study. Stroke 1985; 16: 626–629.

    Article  PubMed  CAS  Google Scholar 

  2. Olshansky B. Syncope: An overview and approach to management. In: Grubb BP, Olshansky B, eds. Syncope: Mechanisms and Management. Futura Publishing Co. Inc., Armonk, NY, 1998, pp. 15–71.

    Google Scholar 

  3. Day SC, Cook EF, Funkenstein H, Goldman L. Evaluation and outcome of emergency room patients with transient loss of consciousness. Am J Med 1982; 73: 15–23.

    Article  PubMed  CAS  Google Scholar 

  4. Olshansky B. Is syncope the same thing as sudden death except that you wake up? J Cardiovasc Electrophysiol 1997; 8: 1098–1101.

    Article  PubMed  CAS  Google Scholar 

  5. Lipsitz LA. Syncope in the elderly. Ann Int Med 1998; 99: 92–104.

    Google Scholar 

  6. Campbell AJ, Teinken J, Allen BC. Falls in old age: a study of frequency and related clinical factors. Age Aging 1981; 10: 264–270.

    Article  CAS  Google Scholar 

  7. Linzer M, Gold DT, Pontinen M. Recurrent syncope as a chronic disease. J Gen Intern Med 1994; 9: 181–186.

    Article  PubMed  CAS  Google Scholar 

  8. Linzer M, Pontinen M, Gold DT, Benarroch E. Impairment of physical and psychological function in recurrent syncope. J Clin Epidemiol 1991; 44: 1037–1043.

    Article  PubMed  CAS  Google Scholar 

  9. Calkins H, Byrne M, El-Atassi R, et al. The economic burden of unrecognized vasodepressor syncope. Am J Med 1993; 35: 473–479.

    Article  Google Scholar 

  10. Kapoor WN, Karpf M, Wieand S, Peterson JR, Levey GS. A prospective evaluation and follow-up of patients with syncope. N Engl J Med 1983; 309: 197–204.

    Article  PubMed  CAS  Google Scholar 

  11. Kapoor WN. An overview of the evaluation and management of syncope. In: Grubb BP, Olshansky B, eds. Syncope: Mechanisms and Management. Futura Publishing Co., Inc., Armonk, NY, 1998, pp. 1–14.

    Google Scholar 

  12. Kapoor WN, Schulberg HC. Psychiatric disorders in patients with syncope. In: Grubb BP, Olshansky B (eds). Syncope: Mechanisms and Management. Futura Publishing Co., Inc., Armonk, NY, 1998, pp. 253–264.

    Google Scholar 

  13. Ferrick KJ, Pacio G, Fisher JD. Limited yield of acute hospitalization for evaluation of syncope. PACE 1997; 20: 1132.

    Google Scholar 

  14. Mozoo B, Confino-Cohen R, Halkin H. Cost-effectiveness of in-hospital evaluation of patients with syncope. Isr J Med Sci 1988; 24: 302–306.

    Google Scholar 

  15. Murray P, Cantwell J, Health D, Shoop J. The role of limited echocardiography in screening athletes. Am J Cardiol 1995; 76: 849–850.

    Article  Google Scholar 

  16. Maron BJ, Bodison SA, Wesley YE, Tucker E, Green KJ. Results of screening a large group of intercollegiate competitive athletes for cardiovascular disease. J Am Coll Cardiol 1987; 1214–1221.

    Google Scholar 

  17. Lewis JF, Maron BJ, Diggs JA, Spencer JE, Mehrotra PP, Curry CL. Pre-participation echocardiographic screening for cardiovascular disease in a large predominantly black population of college athletes. Am J Cardiol 1989; 64: 1029–1033.

    Article  PubMed  CAS  Google Scholar 

  18. Weidenbener CJ, Krauss MD, Waller BF, Taliercio CP. Incorporation of screening echocardiograhy in the pre-participation exam. Clin J Sports Med 1995; 86–89.

    Google Scholar 

  19. Recchia D, Barzila I. Clinical predictors of a normal echocardiogram in patients with syncope. Abstract. Circulation 1994;90(4) Part 2: 1–384.

    Google Scholar 

  20. Sakaguchi S, Schultz J, Remole S, Adler S, Lurie K, Benditt D. Syncope associated with exercise, a manifestation of neurally-mediated syncope. Am J Cardiol 1995; 75: 476–481.

    Article  PubMed  CAS  Google Scholar 

  21. Calkins H, Seifert M, Morady F. Clinical presentation and long term followup of athletes with exercise-induced vasodepressor syncope. Am Heart J 1995; 129: 1159–1164.

    Article  PubMed  CAS  Google Scholar 

  22. Tse H, Lau C. Exercise-associated asystole in persons without structural heart disease. Chest 1995; 107 (2): 572–576.

    Article  PubMed  CAS  Google Scholar 

  23. Sneddon J, Scalia G, Ward D, McKenna W, Camm AJ, Grenneaux M. Exercise-induced vasodepressor syncope. Br Heart J 1994; 71: 554–557.

    Article  PubMed  CAS  Google Scholar 

  24. Kosinski D, Grubb BP, Kip K, Hahn H. Exercise-induced neurocardiogenic syncope: case report. Am Heart J 1996; 132: 451–452.

    Article  PubMed  CAS  Google Scholar 

  25. Osswald S, Brooks P, O’Nunain S, Corwin J, Roelke M, Radvany P, et al. Asystole after exercise in healthy persons. Ann Int Med 1994; 120: 1008–1011.

    Article  PubMed  CAS  Google Scholar 

  26. Fleg JL, Asante AV. Asystole following treadmill exercise in a man without organic heart disease. Arch Int Med 1983; 143: 1821–1822.

    Article  CAS  Google Scholar 

  27. Holtzhausen LM, Noakes T. The prevalence and significance of post exercise hypotension in ultra marathon runners. Med Sci Sports and Ex 1995; 27 (12): 1595–1601.

    CAS  Google Scholar 

  28. Palileo EJ, Ashley WW, Sriryn S. Exercise provocable/right ventricular outflow tachycardia. Am Heart J 1982; 104: 185–193.

    Article  PubMed  CAS  Google Scholar 

  29. Woelfei A, Foster JR, Simpson RJ. Reproducibility and treatment of exercise-induced ventricular tachycardia. Am J Cardiol 1994; 53: 751–756.

    Article  Google Scholar 

  30. Wu D, Kou HC, Hung JS. Exercise-triggered paroxysmal ventricular tachycardia: a repetitive rhythmic activity possibly related to after depolarization. Am Intern Med 1981; 95: 410–414.

    Article  CAS  Google Scholar 

  31. Levy M, Villain E, Phillipe F, Kachaner J. Catecholamine-induced ventricular tachycardia: a cause of severe syncope during adolescence. De Daitrie 1993; 48 (7–8): 533–535.

    CAS  Google Scholar 

  32. Eisenberg S, Scheinman M, Oullet N, Finkbeiner W, Griffin J, Eldar M, et al. Sudden cardiac death and polymorphic ventricular tachycardia in patients with normal QT intervals and normal cardiac systolic function. Am J Cardiol 1995; 75: 687–692.

    Article  PubMed  CAS  Google Scholar 

  33. Coumel P, Leenhardt A, Haddad G. Exercise ECG: prognostic implication of exercise-induced arrhythmias. PACE 1994; 17: 417–427.

    Article  PubMed  CAS  Google Scholar 

  34. Burke A, Farb A, Virmani R, Goodlin J, Smialek J. Sports related and non-sports related sudden cardiac death in young adults. Am Heart J 1991; 121 (2): 568–575.

    Article  PubMed  CAS  Google Scholar 

  35. Burke A, Farb A, Virmani R. Causes of sudden death in athletes. Cardiol Clin 1992; 10 (2): 303–315.

    PubMed  CAS  Google Scholar 

  36. Liberthson RR, Zaman L, Weyman A, Kiger R, Dinsmore R, Leinbach R, et al. Aberrant origin of the left coronary artery from the proximal right coronary artery: diagnostic features and pre-post operative cause. Clin Cardiol 1982; 5: 377–381.

    Article  PubMed  CAS  Google Scholar 

  37. McClellan JT, Jokl E. Congenital anomalies of coronary arteries as a cause of sudden death associated with physical exertion. Med Sport 1971; 5: 91.

    Google Scholar 

  38. Kosinski D, Grubb BP. Neurally-mediated syncope with an update on indications and usefulness of head upright tilt table testing and pharmacologic therapy. Curr Opin Cardiol 1994; 9: 53–54.

    Article  PubMed  CAS  Google Scholar 

  39. Samoil D, Grubb BP. Head upright tilt table testing for recurrent, unexplained syncope. Clin Cardiol 1993; 16: 763–766.

    Article  PubMed  CAS  Google Scholar 

  40. Streiper M, Auld D, Hulse H, Campbell R. Evaluation of recurrent pediatric syncope: role of tilt table test. Pediatrics 1994; 93: 660–662.

    Google Scholar 

  41. Benditt D, Ferguson D, Grubb BP, et al. Tilt table testing for assessing syncope and its treatment: an American College of Cardiology consensus document. J Am Coll Cardiol 1996; 28: 263–275.

    Article  PubMed  CAS  Google Scholar 

  42. Menozzi C, Brignole M, Gaggioli A, et al. Adenosine sensitive syncope in Raviele A. Cardiac Arrhythmias 1999; Springer Verlag, Milan, Italy, 2000; pp. 423–429.

    Book  Google Scholar 

  43. Zipes, et al. Guidelines for intracardiac electrophysiological and catheter ablation procedures. J Am Coll Cardiol 1995; 26 (2): 555–573.

    Google Scholar 

  44. Galmhusein J, Naccarelli G, Ko P, et al. Value and limitations of clinical electrophysiologic study in assessment of patients with unexplained syncope. Am J Med 1982; 73: 700–706.

    Article  Google Scholar 

  45. Benditt D, Remole S, Milstein S, Balin S. Syncope: causes, clinical evaluation, and current therapy. Ann Rev Med 1992; 43: 283–300.

    Article  PubMed  CAS  Google Scholar 

  46. Morady F, Shen E, Schwartz A, Hess D, Bhandari A. Long-term followup of patients with recurrent syncope evaluated by electrophysiologic testing. J Am Coll Cardiol 1983; 2: 1053–1059.

    Article  PubMed  CAS  Google Scholar 

  47. Akhtar M, Shenasa S, Denker S, et al. Role of electrophysiologic studies in patients with unexplained recurrent syncope. PACE 1983; 6: 192–201.

    Article  PubMed  CAS  Google Scholar 

  48. Teichman S, Felder S, Majas J, et al. The value of electrophysiologic studies in syncope of undetermined origin: report of 150 cases. Am Heart J 1985; 110: 469–479.

    Article  PubMed  CAS  Google Scholar 

  49. Crozer I, Kram H. Electrophysiologic evaluation and natural history of unexplained syncope. Aust NZ J Med 1986; 16: 587.

    Google Scholar 

  50. Camm AJ, Lau CP. Syncope of undetermined origin: diagnosis and management. Prog Cardiol 1988; 139–156.

    Google Scholar 

  51. Almquist A, Goldenberg IF, Milstein S., et al. Provocation of bradycardia and hypotension by isoproterenol and upright posture in patients with unexplained syncope. N Engl J Med 1989;320:346– 351.

    Google Scholar 

  52. Sra J, Anderson A, Sheikh H, et al. Unexplained syncope evaluation by electrophysiologic study and head-up tilt testing. Ann Int Med 1991; 114: 1013–1019.

    Article  PubMed  CAS  Google Scholar 

  53. DiMarco J, Philbrick J. Use of ambulatory electrocardiographic monitoring. An Int Med 1990; 113 (1): 53–68.

    Article  CAS  Google Scholar 

  54. Zeldus SM, Leune BJ, Michelson EL, Morganroth J. Cardiovascular complaints: correlation with cardiac arrhythmias on 24-hour electrocardiographic monitoring. Chest 1980; 78: 456–461.

    Article  Google Scholar 

  55. Clark P, Glasser SP, Sporo E. Arrhythmias detected by ambulatory monitoring: lack of correlation with symptoms of dizziness and syncope. Chest 1980; 77: 722–725.

    Article  PubMed  CAS  Google Scholar 

  56. Jonas S, Klein I, Dimant J. Importance of Holter monitoring in patients with periodic cerebral symptoms. Amn Neurol 1977; 1: 470–474.

    Article  CAS  Google Scholar 

  57. Kala R, Vittasalo M, Toivonen L, Eisalo A. Ambulatory ECG recording in patients with dizziness or syncope. ACTA Med Scand 1982; 688 (Supp): 13–19.

    Google Scholar 

  58. Gilton TC, Heitzman MR. Diagnostic efficacy of 24-hour electrocardiographic monitoring for syncope. Am J Cardiol 1984; 53: 1013–1017.

    Article  Google Scholar 

  59. Boudoulas H, Schaal SF, Lewis RP, Robinson JL. Superiority of 24-hour outpatient monitoring over multi-stage exercise testing for the evaluation of syncope. J Electrocardiol 1979; 12: 103–108.

    Article  PubMed  CAS  Google Scholar 

  60. Diamond TH, Smith R, Myburgh D. Holter monitoring—a necessity for the evaluation of palpitations. S Afr Med J 1983; 63: 5–7.

    PubMed  CAS  Google Scholar 

  61. Pasyk S, Sredniawa B. Holter monitoring in the diagnosis of syncope. Pulske Tygodnik Lekarski 1993; 48 (16–17): 377–379.

    CAS  Google Scholar 

  62. Racco F, Sconocchini C, Reginelli R, Brizzi G, Alessi C, Rosario S, et al. Value of cardiac electrocardiographic monitoring of patients with syncope: results of a prospective study. Minerva Cardioangiol 1993; 41 (11): 523–527.

    PubMed  CAS  Google Scholar 

  63. Beauregard L, Fabiszewski R, Black CH, Lightfoot B, Schraeder PL, Toly T, et al. Combined ambulatory electroencephalographic and electrocardiographic monitoring for evaluation of syncope. Am J Cardiol 1991; 68 (10): 1067–1072.

    Article  PubMed  CAS  Google Scholar 

  64. Braun A, Dawkins K, Davies J. Detection of arrhythmias: use of a patient-activated ambulatory electrocardiogram device with a solid state memory loop. Br Heart J 1987; 58: 251–253.

    Article  Google Scholar 

  65. Kinlay S, Leitch J, Neil A, Chapman B, Hardy D, Fletcher P. Cardiac event recorders yield more diagnoses and are more cost effective than 48-hour Holter monitoring in patients with palpitations. Ann Int Med 1996; 124 (1): 16–20.

    PubMed  CAS  Google Scholar 

  66. Krahn A, Klein G, Norris C, Yee R. The etiology of syncope in patients with negative tilt table testing and electrophysiologic testing. Circulation 1995; 42 (7): 1819–1824.

    Article  Google Scholar 

  67. Kuchar DL, Thorburn CW, Sannuel NL. Signal averaged electrocardiogram for evaluation of recurrent syncope. Am J Cardiol 1986; 58: 949–953.

    Article  PubMed  CAS  Google Scholar 

  68. Gang ES, Peter T, Rosenthal ME. Detection of late potentials in the surface electrocardiogram in unexplained syncope. Am J Cardiol 1986; 58: 1014–1020.

    Article  PubMed  CAS  Google Scholar 

  69. Winters SL, Stewart D, Gome J. Signal averaging of the surface QRS complex predicts inducibility of ventricular tachycardia in patients with syncope of unknown etiology: a prospective study. J Am Coll Cardiol 1988; 12: 1481–1487.

    Article  PubMed  CAS  Google Scholar 

  70. Buxton A. Late potentials and syncope. In: El-Sherif N, Turitto G, eds. High Resolution Echocardiography. Futura Publishing Co., Inc., Mount Kisko, NY, 1992, pp. 521–532.

    Google Scholar 

  71. Kjellgren D, Gomes J. Current usefulness of the signal averaged electrocardiogram. Curr Prob and Cardiol 1993; 18 (6): 396–398.

    Google Scholar 

  72. Morillo C, Zandri S, Klein G, Yee R. Usefulness of signal averaged ECG, head-up tilt and electrophysiologic study in patients with unexplained syncope. J Am Coll Cardiol 1995; 21: 92.

    Article  Google Scholar 

  73. Benarroch E. The central autonomic network: functional organization, dysfunction and perspective. Mayo Clinic Proc 1993; 68: 988–1001.

    Article  CAS  Google Scholar 

  74. Wieling W, Lieshout J. Maintenance of postural normotension in humans. In: Low P., ed. Clinical Autonomic Disorders. Little Brown Co., 1993, pp. 69–73.

    Google Scholar 

  75. Grubb BP. Neurocardiogenic syncope. In: Grubb BP, Olshansky B, eds. Syncope: Mechanisms and Management. Futura Publishing, Armonk, NY, 1998, in press.

    Google Scholar 

  76. Kosinski D, Grubb BP, Temesy-Armos P. Pathophysiological aspects of neurocardiogenic syncope. PACE 1995; 18: 716–721.

    Google Scholar 

  77. Sutton R, Petersen M. The clinical spectrum of neurocardiogenic syncope. J Cardiovasc Electrophysiol 1995; 6: 569–576.

    Article  PubMed  CAS  Google Scholar 

  78. Kosinski D. Miscellaneous causes of syncope. In: Grubb BP, Olshansky B, eds. Syncope: Mechanisms and Management. Futura Publishing, Armonk, NY, 1998, in press.

    Google Scholar 

  79. Bradbury S, Eggleston C. Postural hypotension: a report of three cases. Jam Heart J 1925; 1: 73–86.

    Article  Google Scholar 

  80. Robertson D, Polinsky R, eds. A Primer on the Autonomic Nervous System. Academic Press, San Diego, CA, 1996.

    Google Scholar 

  81. Shy GM, Drager GA. A neurologic syndrome associated with orthostatic hypotension. Arch Neurol 1960; 3: 511–527.

    Article  Google Scholar 

  82. Mathias CJ. The classification and nomenclature of autonomic disorders: ending chaos, restoring conflict, and hopefully achieving clarity. Clin Auton Res 1995; 5: 307–310.

    Article  PubMed  CAS  Google Scholar 

  83. Grubb BP, Kosinski D, Boehm K, Kip K. The postural orthostatic tachycardia syndrome: a neurocardiogenic variant identified during head up tilt table testing. PACE 1997; 20: 2205–2212.

    Article  PubMed  CAS  Google Scholar 

  84. Bou-Holaigh I, Rowe P, Kan J, Calkins H. The relationship between neurally mediated hypotension and chronic fatigue syndrome. JAMA 1995; 274: 961–967.

    Article  Google Scholar 

  85. Grubb BP, Kosinski D. Acute pandysautonomic syncope. Eur J of Cardiac Pacing and Electrophysiol 1997; 7: 10–14.

    Google Scholar 

  86. Passant V, Warkentin S, Karlson, et al. Orthostatic hypotension in organic dementia: relationship between blood pressure, cortical blood flow, and symptoms. Clin Auton Res 1996; 6: 29–36.

    Article  PubMed  CAS  Google Scholar 

  87. Bannister R, Mathias C, eds. Autonomic Failure: A Textbook of Clinical Disorders of the Autonomic Nervous System. Oxford Medical Publications, Oxford, 1992.

    Google Scholar 

  88. Low P, ed. Clinical Autonomic Disorders. Little Brown Co., Boston, 1993.

    Google Scholar 

  89. Grubb BP, Olshansky B, eds. Syncope: Mechanisms and Management. Futura Publishing, Armonk, NY, 1997.

    Google Scholar 

  90. Robertson D, Biaggioni I, eds. Disorders of the Autonomic Nervous System. Harwood Academic Publishers, London, 1995.

    Google Scholar 

  91. Grubb BP, Kosinski D. Tilt table testing: Concepts and limitations. PACE 1997; 20 (Part II): 781–787.

    Google Scholar 

  92. Mahanonda N, Bhuripanyo K, Kangkagate C,Randomized double blind placebo-controlled trial of oral atenolol in patients with unexplained syncope and positive upright tilt test results. Am Heart J 1995; 18: 655–662.

    Google Scholar 

  93. Scott WA, Pongiglione G, Bromberg BL, et al. Randomized comparison of atenolol and fludrocortisone acetate in the treatment of pediatric neurally-mediated syncope. Am J Cardiol 1995; 76: 400–402.

    Article  PubMed  CAS  Google Scholar 

  94. Grubb BP, Kosinski D, Mouhaffel A, Pothoulakis A. The use of methylphenidate in the treatment of refractory neurocardiogenic syncope. PACE 1996; 19: 836–840.

    Article  PubMed  CAS  Google Scholar 

  95. Low P, Gilden J, Freeman R, et al. Efficacy of midodrine vs placebo in neurocardiogenic orthostatic hypotension. JAMA 1997; 277: 1046–1051.

    Article  PubMed  CAS  Google Scholar 

  96. Sra J, Maglio C, Biehl M, et al. Efficacy of midodrine hydrochloride in neurocardiogenic syncope refractory to standard therapy. J Cardiovasc Electrophysiol 1997; 8: 42–46.

    Article  PubMed  CAS  Google Scholar 

  97. Ward CR, Gray JC, Gilroy JJ, Kenny RA. Midodrine: a role in the management of neurocardiogenic syncope. Heart 1998; 79: 45–49.

    PubMed  CAS  Google Scholar 

  98. Robertson D, Davis TL. Recent advances in the treatment of orthostatic hypotension. Neurology 1995; 5: 526–532.

    Google Scholar 

  99. Hoeldtke RD, Streeton DH. Treatment of orthostatic hypotension with erythropoietin. N Engl J Med 1993; 329: 611–615.

    Article  PubMed  CAS  Google Scholar 

  100. Grubb BP, Lachant N, Kosinski D. Erythropoietin as a therapy for severe refractory orthostatic hypotension. Clin Auton Res 1994; 4: 212.

    Google Scholar 

  101. Grubb BP, Kosinski D. Serotonin and syncope: an emerging connection? Eur J Cardiac Pacing Electrophysiol 1996; 5: 306–314.

    Google Scholar 

  102. Girolamo ED, Iorio CD, Sabatini P, et al. Effects of paroxetine hydrochloride, a selective serotonin reuptake inhibitor on refractory neurocardiogenic syncope: a randomized double blind placebo-controlled study. J Am Coll Cardiol 1999; 33: 1227–1230.

    Article  PubMed  Google Scholar 

  103. Grubb BP, Samoil D, Kosinski D, et al. Fluoxetine hydrochloride for the treatment of severe refractory orthostatic hypotension. PACE 1993; 16: 801–805.

    Article  PubMed  CAS  Google Scholar 

  104. Benditt D, Petersen ME, Luriek, et al. Cardiac pacing for prevention of recurrent vasovagal syncope. Ann Int Med 1995; 122: 204–209.

    Article  PubMed  CAS  Google Scholar 

  105. Connolly SJ, Sheldon RS, Roberts RS, Gent M. The North American vasovagal pacemaker study: a randomized trial of permanent cardiac pacing for prevention of vasovagal syncope. J Am Coll Cardiol 1999; 33: 16–20.

    Google Scholar 

  106. Sutton R, Brignole M, Menozzi C, et al. Dual chamber pacing in the treatment of neurally mediated tilt positive cardioinhibitory syncope: pacemaker versus no therapy: a multicenter randomized study. Circulation 2000; 102: 294–299.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer Science+Business Media New York

About this chapter

Cite this chapter

Grubb, B.P., Kosinski, D. (2002). Evaluation and Management of Syncope. In: Ganz, L.I. (eds) Management of Cardiac Arrhythmias. Contemporary Cardiology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-090-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-090-2_10

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-218-6

  • Online ISBN: 978-1-59259-090-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics