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Trace Element and Mineral Nutrition in HIV Infection and AIDS

Implications for Host Defense

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Book cover Clinical Nutrition of the Essential Trace Elements and Minerals

Part of the book series: Nutrition ◊ and ◊ Health ((NH))

Abstract

The essential trace elements and minerals obtained from the diet are crucial for the development and maintenance of life at every level and affect all aspects of human health from the formation of cells, tissues, and organs to the initiation and development of host defense by the immune system in response to foreign microbes and viruses. This chapter will focus on how changes in body stores of trace elements and minerals in the human immunodeficiency virus (HIV)+ host may affect the course of HIV disease and influence progression to acquired immune-deficiency syndrome (AIDS). Since HIV infection directly affects the immune system, by specifically targeting the CD4+ T cell, the fundamental nature of the immune response is intrinsically changed by this unique infection. As described below, trace elements and minerals interact and regulate the development of normal immune responses in such a way that relatively small changes in available pools may have a proportionately greater or amplified impact on immune function compared with effects on other cell systems (1,2).

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Authors
  1. Susanna Cunningham-Rundles PhD
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Editors and Affiliations

  1. Department of Preventive Medicine and Community Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA

    John D. Bogden PhD

  2. United States Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND, USA

    Leslie M. Klevay MD, SD in Hyg

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Cunningham-Rundles, S. (2000). Trace Element and Mineral Nutrition in HIV Infection and AIDS. In: Bogden, J.D., Klevay, L.M. (eds) Clinical Nutrition of the Essential Trace Elements and Minerals. Nutrition ◊ and ◊ Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-040-7_19

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  • DOI: https://doi.org/10.1007/978-1-59259-040-7_19

  • Publisher Name: Humana Press, Totowa, NJ

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